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中国科学院海洋研究所机构知识库
Knowledge Management System Of Institute of Oceanology, Chinese Academy of Sciences
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The Fluoro-Thiazolylhydrazone Compound TSC-3C Inhibits Triple Negative Breast Cancer (TNBC) Cell Line Activity by Promoting Apoptosis, Regulating the MAPK Pathway and Inducing Mitochondrial Dysfunction
期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2020, 卷号: 21, 期号: 3, 页码: 15
作者:
Zhang, Jiajia
;
Dai, Jiajia
;
Zheng, Qingxuan
;
Guo, Shuju
;
Yu, Yanyan
;
Hu, Wenpeng
;
Gao, Yanan
;
Shi, Dayong
Adobe PDF(2858Kb)
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浏览/下载:267/0
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提交时间:2020/09/23
triple negative breast cancer
MDA-MB-231 cells
fluoro-thiazolylhydrazone
MAPK pathway
phosphorylated p44/42 MAPK (ERK1/2)
phosphorylated c-Jun N-terminal kinase (p-JNK)
apoptosis
A novel protein from Eupolyphaga sinensis inhibits adhesion, migration, and invasion of human lung cancer A549 cells
期刊论文
BIOCHEMISTRY AND CELL BIOLOGY-BIOCHIMIE ET BIOLOGIE CELLULAIRE, 2013, 卷号: 91, 期号: 4, 页码: 244-251
作者:
Wang, Feng-xia
;
Wu, Ning
;
Wei, Jian-teng
;
Liu, Jia
;
Zhao, Jin
;
Ji, Ai-guo
;
Lin, Xiu-kun
;
Lin, XK
Adobe PDF(2911Kb)
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浏览/下载:331/0
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提交时间:2014/07/17
Anticancer Protein
Antimetastatic Activity
Eupolyphaga Sinensis
Beta 1-integrin
Lung Cancer A549 Cells
Chimeric 5/35 adenovirus-mediated Dickkopf-1 overexpression suppressed tumorigenicity of CD44(+) gastric cancer cells via attenuating Wnt signaling
期刊论文
JOURNAL OF GASTROENTEROLOGY, 2013, 卷号: 48, 期号: 7, 页码: 798-808
作者:
Wang, Bin
;
Liu, Jia
;
Ma, Lei Na
;
Xiao, Hua Liang
;
Wang, Ya Zhou
;
Li, Yan
;
Wang, Zhe
;
Fan, Linli
;
Lan, Chunhui
;
Yang, Min
;
Hu, Lu
;
Wei, Yanlin
;
Bian, Xiu Wu
;
Chen, Dongfeng
;
Wang, Jun
;
Chen, DF
Adobe PDF(686Kb)
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浏览/下载:363/0
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提交时间:2014/07/17
Gastric Carcinoma
Cancer Stem Cells
Gene Therapy
Dickkopf-1
Oleanolic acid potentiates the antitumor activity of 5-fluorouracil in pancreatic cancer cells
期刊论文
ONCOLOGY REPORTS, 2012, 卷号: 28, 期号: 4, 页码: 1339-1345
作者:
Wei, Jianteng
;
Liu, Haizhou
;
Liu, Ming
;
Wu, Ning
;
Zhao, Jin
;
Xiao, Lin
;
Han, Lijun
;
Chu, Edward
;
Lin, Xiukun
;
Lin, XK (reprint author), Chinese Acad Sci, Inst Oceanol, 7 Nanhai Rd, Qingdao 266071, Peoples R China.
Adobe PDF(762Kb)
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浏览/下载:349/0
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提交时间:2013/09/24
Apoptosis
Oleanolic Acid
5-fluorouracil
Pancreatic Cancer Cells
Synergism
siRNA targeting Notch-1 decreases glioma stem cell proliferation and tumor growth
期刊论文
MOLECULAR BIOLOGY REPORTS, 2012, 卷号: 39, 期号: 3, 页码: 2497-2503
作者:
Wang, Jianpeng
;
Wang, Chao
;
Meng, Qinghai
;
Li, Shifang
;
Sun, Xiaopeng
;
Bo, Yongli
;
Yao, Weicheng
;
Yao, WC (reprint author), Qingdao Univ, Coll Med, Affiliated Hosp, Dept Neurosurg, 16 Jiangsu Rd, Qingdao 266003, Shandong, Peoples R China.
Adobe PDF(381Kb)
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浏览/下载:271/0
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提交时间:2013/09/24
Initiating Cells
Glioblastoma-multiforme
Side Population
Breast-cancer
Pathway
Expression
Xenografts
Activation
Phenotype
Survival
Interaction between Thymidylate Synthase and Its Cognate mRNA in Zebrafish Embryos
期刊论文
PLOS ONE, 2010, 卷号: 5, 期号: 5, 页码: e10618
作者:
Zhang, Yuyan
;
Yang, Shaoli
;
Liu, Ming
;
Song, Chunxia
;
Wu, Ning
;
Ling, Peixue
;
Chu, Edward
;
Lin, Xiukun
;
Zhang, YY, Chinese Acad Sci, Inst Oceanol, Qingdao, Peoples R China
Adobe PDF(545Kb)
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浏览/下载:214/1
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提交时间:2010/11/18
Binding
Protein
Autoregulation
Degradation
Expression
Induction
Mechanism
Residues
Cancer
Cells
Interaction between Thymidylate Synthase and Its Cognate mRNA in Zebrafish Embryos
期刊论文
PLOS ONE, 2010, 卷号: 5, 期号: 5, 页码: e10618
作者:
Zhang, Yuyan
;
Yang, Shaoli
;
Liu, Ming
;
Song, Chunxia
;
Wu, Ning
;
Ling, Peixue
;
Chu, Edward
;
Lin, Xiukun
;
Zhang, YY, Chinese Acad Sci, Inst Oceanol, Qingdao, Peoples R China
Adobe PDF(545Kb)
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浏览/下载:209/0
  |  
提交时间:2010/11/18
Binding
Protein
Autoregulation
Degradation
Expression
Induction
Mechanism
Residues
Cancer
Cells
Aberrant expression of X-linked genes RbAp46, Rsk4, and Cldn2 in breast cancer
期刊论文
MOLECULAR CANCER RESEARCH, 2007, 卷号: 5, 期号: 2, 页码: 171-181
作者:
Thakur, Archana
;
Rahman, K. M. Wahidur
;
Wu, Jack
;
Bollig, Aliccia
;
Biliran, Hector
;
Lin, Xiukun
;
Nassar, Hind
;
Grignon, David J.
;
Sarkar, Fazlul H.
;
Liao, Joshua D.
;
Rahman, KMW, Wayne State Univ, Dept Pathol, Karmanos Canc Inst, 110 E Warren Ave, Detroit, MI 48201 USA
Adobe PDF(693Kb)
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浏览/下载:238/0
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提交时间:2010/11/18
Active-x
Chromosome Inactivation
Brca1 Mutation
Ovarian-cancer
High-frequency
Barr Body
Cells
Carcinoma
Kinase
Components
Identification of norharman as the cytotoxic compound produced by the sponge (Hymeniacidon perleve)-associated marine bacterium Pseudoalteromonas piscicida and its apoptotic effect on cancer cells
期刊论文
BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY, 2006, 卷号: 44, 页码: 135-142
作者:
Zheng, L
;
Yan, XJ
;
Han, XT
;
Chen, HM
;
Lin, W
;
Lee, FSC
;
Wang, XR
Adobe PDF(334Kb)
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浏览/下载:232/0
  |  
提交时间:2015/07/19
Cancer Cells
Cytotoxic Activity
Sponge (Hymeniacidon Perleve)-associated Marine Bacterium (Pseudoalteromonas Piscicida)
Norharman (9h-pyrido[3
4-b]Indole Or 2-azacarbazole)
Insulin-like growth factor-binding protein-3 plays an important role in regulating pharyngeal skeleton and inner ear formation and differentiation
期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2005, 卷号: 280, 期号: 5, 页码: 3613-3620
作者:
Li, Y
;
Xiang, JH
;
Duan, CM
;
Duan, CM, Univ Michigan, Dept Mol Cellular & Dev Biol, Kraus Nat Sci Bldg, Ann Arbor, MI 48109 USA
Adobe PDF(409Kb)
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浏览/下载:230/0
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提交时间:2010/11/18
Factor Igf Binding
Factor-i
Messenger-rnas
Developmental Expression
Cellular-localization
Targeted Disruption
Nuclear Transport
Cancer Cells
Zebrafish
Receptor