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Structural and Bioactive Studies of Halogenated Constituents from Sponges 期刊论文
CURRENT MEDICINAL CHEMISTRY, 2020, 卷号: 27, 期号: 14, 页码: 2335-2360
作者:  Li, Chao;  Shi, Dayong
收藏  |  浏览/下载：308/0  |  提交时间：2020/09/24
Halogenated  sponges  marine  isolate  constitutes  activity  
Ligand- and Additive-Free 2-Position-Selective Trifluoromethylation of Heteroarenes Under Ambient Conditions 期刊论文
FRONTIERS IN CHEMISTRY, 2019, 卷号: 7, 页码: 10
作者:  Shi, Xiaolin;  Li, Xiaowei;  Li, Xiangqian;  Shi, Dayong
Adobe PDF(988Kb)  |  收藏  |  浏览/下载：401/0  |  提交时间：2020/01/03
C-H functionalization  trifluoromethylation  indoles  copper  radical reaction  
Cu(II)-Catalyzed Oxidative Trifluoromethylation of Indoles with KF as the Base 期刊论文
CATALYSTS, 2019, 卷号: 9, 期号: 3, 页码: 14
作者:  Shi, Xiaolin;  Li, Xiaowei;  Ma, Lina;  Shi, Dayong
Adobe PDF(1208Kb)  |  收藏  |  浏览/下载：402/0  |  提交时间：2019/08/28
Cu(II) catalyst  Langlois reagent  trifluoromethylation  indole  radical reaction  
Halogenated Compounds from Corals: Chemical Diversity and Biological Activities 期刊论文
MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2019, 卷号: 19, 期号: 15, 页码: 1204-1218
作者:  Zhang, Yuanyuan;  Liu, Junhong;  Shi, Dayong;  Li, Zheng
收藏  |  浏览/下载：201/0  |  提交时间：2020/09/21
Marine  corals  metabolites  halogenated  bioactivity  chemical diversity  
Iron-catalyzed alkynylation of tertiary aliphatic amines with 1-iodoalkynes to synthesize propargylamines 期刊论文
ORGANIC CHEMISTRY FRONTIERS, 2018, 卷号: 5, 期号: 24, 页码: 3515-3519
作者:  Ma, Lina;  Shi, Xiaolin;  Li, Xiaowei;  Shi, Dayong
Adobe PDF(601Kb)  |  收藏  |  浏览/下载：307/0  |  提交时间：2019/05/15
Design, synthesis and biological evaluation of novel pyrimidinedione derivatives as DPP-4 inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 28, 期号: 12, 页码: 2131-2135
作者:  Li, Ning;  Wang, Li-Jun;  Jiang, Bo;  Guo, Shu-Ju;  Li, Xiang-Qian;  Chen, Xue-Chun;  Luo, Jiao;  Li, Chao;  Wang, Yi;  Shi, Da-Yong
Adobe PDF(824Kb)  |  收藏  |  浏览/下载：376/0  |  提交时间：2019/08/21
Pyrimidinedionederivatives  DPP-4 inhibitor  Molecular hybrid  SARs  Type 2 diabetes  
Recent progress of the development of dipeptidyl peptidase-4 inhibitors for the treatment of type 2 diabetes mellitus 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 151, 页码: 145-157
作者:  Li, Ning;  Wang, Li-Jun;  Jiang, Bo;  Li, Xiang-qian;  Guo, Chuan-long;  Guo, Shu-ju;  Shi, Da-Yong
Adobe PDF(1523Kb)  |  收藏  |  浏览/下载：387/0  |  提交时间：2019/08/21
DPP-4  Inhibitors  Analogs  Physico-chemical properties  SARs  Type 2 diabetes  
A Novel Bromophenol Derivative BOS-102 Induces Cell Cycle Arrest and Apoptosis in Human A549 Lung Cancer Cells via ROS-Mediated PI3K/Akt and the MAPK Signaling Pathway 期刊论文
MARINE DRUGS, 2018, 卷号: 16, 期号: 2, 页码: 13
作者:  Guo, Chuan-Long;  Wang, Li-Jun;  Zhao, Yue;  Liu, Hua;  Li, Xiang-Qian;  Jiang, Bo;  Luo, Jiao;  Guo, Shu-Ju;  Wu, Ning;  Shi, Da-Yong
Adobe PDF(5208Kb)  |  收藏  |  浏览/下载：436/0  |  提交时间：2019/08/21
bromophenol  molecular mechanisms  apoptosis  cell cycle  PI3K  Akt  p38  ERK  ROS  human lung cancer  
Selectivity, cell permeability and oral availability studies of novel bromophenol derivative HPN as protein tyrosine phosphatase 1B inhibitor 期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2018, 卷号: 175, 期号: 1, 页码: 140-153
作者:  Luo, Jiao;  Xu, Qi;  Jiang, Bo;  Zhang, Renshuai;  Jia, Xiaoling;  Li, Xiangqian;  Wang, Lijun;  Guo, Chuanlong;  Wu, Ning;  Shi, Dayong
Adobe PDF(2211Kb)  |  收藏  |  浏览/下载：346/0  |  提交时间：2019/08/20
Recent Advances in Transition-metal-catalyzed Halides Formation 期刊论文
CURRENT ORGANIC CHEMISTRY, 2018, 卷号: 22, 期号: 23, 页码: 2229-2255
作者:  Shi, Xiaolin;  Shi, Dayong
Adobe PDF(1243Kb)  |  收藏  |  浏览/下载：261/0  |  提交时间：2019/05/15
Catalysis  C-X bond  halides formation  halogenated  organohalides  palladium  transition metals