| Iron-catalyzed alkynylation of tertiary aliphatic amines with 1-iodoalkynes to synthesize propargylamines |
| Ma, Lina1,2,3; Shi, Xiaolin1,2,3; Li, Xiaowei1,2,3 ; Shi, Dayong1,2,3
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| 2018-12-21
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| 发表期刊 | ORGANIC CHEMISTRY FRONTIERS
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| ISSN | 2052-4129
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| 卷号 | 5期号:24页码:3515-3519 |
| 通讯作者 | Shi, Dayong([email protected])
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| 摘要 | A method of alkynylation of tertiary aliphatic amines with 1-iodoalkynes has been developed in the presence of FeCl2 as a catalyst and tert-butyl hydroperoxide as an oxidant. With this method, a variety of propargylamines were obtained in good to excellent yields from inexpensive and readily available reagents. The studies on the possible reaction pathway suggest that this reaction proceeds through a radical process. |
| DOI | 10.1039/c8qo01028e
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| 收录类别 | SCI
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| 语种 | 英语
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| 资助项目 | CPSF-CAS Joint Foundation for Excellent Postdoctoral Fellows[2017LH024]###579; National Natural Science Foundation of China[81773586]###283; National Natural Science Foundation of China[81703354]###282; Key research and development project of Shandong province[2016GSF201193]###551; Key research and development project of Shandong province[2016ZDJS07A13]###285; Key research and development project of Shandong province[2016GSF115002]###552; Key research and development project of Shandong province[2016GSF115009]###553; Key Research Program of Frontier Sciences, CAS[QYZDB-SSW-DQC014]###580; Shandong Provincial Natural Science Foundation for Distinguished Young Scholars[JQ201722]###556; National Program for Support of Top-notch Young Professionals###557; Taishan scholar Youth Project of Shandong province###558; Project of Discovery, Evaluation and Transformation of Active Natural Compounds, Strategic Biological Resources Service Network Program of the Chinese Academy of Sciences[ZSTH-026]###581; CPSF-CAS Joint Foundation for Excellent Postdoctoral Fellows[2017LH024]; National Natural Science Foundation of China[81773586]; National Natural Science Foundation of China[81703354]; Key Research and Development Project of Shandong Province[2016GSF201193]; Key Research and Development Project of Shandong Province[2016ZDJS07A13]; Key Research and Development Project of Shandong Province[2016GSF115002]; Key Research and Development Project of Shandong Province[2016GSF115009]; Key Research Program of Frontier Sciences, CAS[QYZDB-SSW-DQC014]; Shandong Provincial Natural Science Foundation for Distinguished Young Scholars[JQ201722]; National Program for Support of Top-notch Young Professionals; Taishan Scholar Youth Project of Shandong Province; Project of Discovery, Evaluation and Transformation of Active Natural Compounds, Strategic Biological Resources Service Network Program of the Chinese Academy of Sciences[ZSTH-026] |
| WOS研究方向 | Chemistry
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| WOS类目 | Chemistry, Organic
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| WOS记录号 | WOS:000452114300003
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| 出版者 | ROYAL SOC CHEMISTRY
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| 引用统计 |
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| 文献类型 | 期刊论文
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| 条目标识符 | http://ir.qdio.ac.cn/handle/337002/155796
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| 专题 | 实验海洋生物学重点实验室
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| 通讯作者 | Shi, Dayong |
| 作者单位 | 1.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China
2.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Drugs & Bioprod, Qingdao 266237, Peoples R China
3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
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| 第一作者单位 | 实验海洋生物学重点实验室
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| 通讯作者单位 | 实验海洋生物学重点实验室
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推荐引用方式
GB/T 7714 |
Ma, Lina,Shi, Xiaolin,Li, Xiaowei,et al. Iron-catalyzed alkynylation of tertiary aliphatic amines with 1-iodoalkynes to synthesize propargylamines[J]. ORGANIC CHEMISTRY FRONTIERS,2018,5(24):3515-3519.
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| APA |
Ma, Lina,Shi, Xiaolin,Li, Xiaowei,&Shi, Dayong.(2018).Iron-catalyzed alkynylation of tertiary aliphatic amines with 1-iodoalkynes to synthesize propargylamines.ORGANIC CHEMISTRY FRONTIERS,5(24),3515-3519.
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| MLA |
Ma, Lina,et al."Iron-catalyzed alkynylation of tertiary aliphatic amines with 1-iodoalkynes to synthesize propargylamines".ORGANIC CHEMISTRY FRONTIERS 5.24(2018):3515-3519.
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