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Oleanolic acid inhibits proliferation and invasiveness of Kras-transformed cells via autophagy 期刊论文
JOURNAL OF NUTRITIONAL BIOCHEMISTRY, 2014, 卷号: 25, 期号: 11, 页码: 1154-1160
作者:  Liu, Jia;  Zheng, Lanhong;  Ma, Leina;  Wang, Bin;  Zhao, Youguang;  Wu, Ning;  Liu, Ge;  Lin, Xiukun;  Lin, XK (reprint author), Capital Med Univ, Dept Pharmacol, Beijing 100069, Peoples R China.
Adobe PDF(926Kb)  |  收藏  |  浏览/下载:304/0  |  提交时间:2015/06/11
Oleanolic Acid  Autophagy  Akt  Cancer Prevention  Natural Compounds  
Aplysin Sensitizes Cancer Cells to TRAIL by Suppressing P38 MAPK/Survivin Pathway 期刊论文
MARINE DRUGS, 2014, 卷号: 12, 期号: 9, 页码: 5072-5088
作者:  Liu, Jia;  Ma, Leina;  Wu, Ning;  Liu, Ge;  Zheng, Lanhong;  Lin, Xiukun;  Zheng, LH (reprint author), Chinese Acad Fishery Sci, Yellow Sea Fisheries Res Inst, Qingdao 266071, Peoples R China.
Adobe PDF(920Kb)  |  收藏  |  浏览/下载:267/0  |  提交时间:2015/06/11
Aplysin  Trail  P38 Mapk  Survivin  
Oleanolic acid induces protective autophagy in cancer cells through the JNK and mTOR pathways 期刊论文
ONCOLOGY REPORTS, 2014, 卷号: 32, 期号: 2, 页码: 567-572
作者:  Liu, Jia;  Zheng, Lanhong;  Zhong, Jiateng;  Wu, Ning;  Liu, Ge;  Lin, Xiukun;  Zheng, LH (reprint author), Chinese Acad Fishery Sci, Yellow Sea Fisheries Res Inst, 7 Nanhai Rd, Qingdao 266071, Shandong, Peoples R China.
Adobe PDF(926Kb)  |  收藏  |  浏览/下载:252/0  |  提交时间:2015/06/11
Oleanolic Acid  Autophagy  Cancer  Mammalian Target Of Rapamycin  C-jun N-terminal Kinase  
Oleanolic Acid Induces Metabolic Adaptation in Cancer Cells by Activating the AMP-Activated Protein Kinase Pathway 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2014, 卷号: 62, 期号: 24, 页码: 5528-5537
作者:  Liu, Jia;  Zheng, Lanhong;  Wu, Ning;  Ma, Leina;  Zhong, Jiateng;  Liu, Ge;  Lin, Xiukun;  Lin, XK (reprint author), Chinese Acad Sci, Inst Oceanol, Qingdao 266071, Peoples R China.
Adobe PDF(4102Kb)  |  收藏  |  浏览/下载:301/0  |  提交时间:2015/06/11
Aerobic Glycolysis  Ampk  Metabolism  Oleanolic Acid  
CS5931, a Novel Polypeptide in Ciona savignyi, Represses Angiogenesis via Inhibiting Vascular Endothelial Growth Factor (VEGF) and Matrix Metalloproteinases (MMPs) 期刊论文
MARINE DRUGS, 2014, 卷号: 12, 期号: 3, 页码: 1530-1544
作者:  Liu, Ge;  Liu, Ming;  Wei, Jianteng;  Huang, Haijuan;  Zhang, Yuyan;  Zhao, Jin;  Xiao, Lin;  Wu, Ning;  Zheng, Lanhong;  Lin, Xiukun;  Liu, M (reprint author), Ocean Univ China, Sch Med & Pharm, Minist Educ, Key Lab Marine Drugs, Qingdao 266003, Peoples R China.
Adobe PDF(1171Kb)  |  收藏  |  浏览/下载:323/0  |  提交时间:2015/06/11
Zebrafish  Anti-angiogenesis  Huvecs  Cs5931  Vegf And Mmps  
Targeting cellular apoptotic pathway with peptides from marine organisms 期刊论文
BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER, 2013, 卷号: 1836, 期号: 1, 页码: 42-48
作者:  Zheng, Lanhong;  Lin, Xiukun;  Wu, Ning;  Liu, Ming;  Zheng, Yuan;  Sheng, Jun;  Ji, Xiaofeng;  Sun, Mi;  Lin, XK
Adobe PDF(440Kb)  |  收藏  |  浏览/下载:401/0  |  提交时间:2014/07/17
Apoptosis  Marine Organisms  Peptides  
Cloning, characterization and expression of a cDNA encoding a granulin-like polypeptide in Ciona savignyi 期刊论文
BIOCHIMIE, 2013, 卷号: 95, 期号: 8, 页码: 1611-1619
作者:  Zhao, Jin;  Wei, Jianteng;  Liu, Ming;  Xiao, Lin;  Wu, Ning;  Liu, Ge;  Huang, Haijuan;  Zhang, Yuyan;  Zheng, Lanhong;  Lin, Xiukun;  Lin, XK
Adobe PDF(2060Kb)  |  收藏  |  浏览/下载:280/0  |  提交时间:2014/07/17
Ciona Savignyi  Granulin  Antitumor Polypeptide  Apoptosis  
A Novel Polypeptide Extracted From Ciona savignyi Induces Apoptosis Through a Mitochondrial-Mediated Pathway in Human Colorectal Carcinoma Cells 期刊论文
CLINICAL COLORECTAL CANCER, 2012, 卷号: 11, 期号: 3, 页码: 207-214
作者:  Cheng, Linyou;  Wang, Chunguang;  Liu, Haizhou;  Wang, Fengxia;  Zheng, Lanhong;  Zhao, Jin;  Chu, Edward;  Lin, Xiukun;  Lin, XK (reprint author), Chinese Acad Sci, Inst Oceanol, Qingdao 266071, Peoples R China.
Adobe PDF(1549Kb)  |  收藏  |  浏览/下载:308/0  |  提交时间:2013/09/24
Antitumor  Ciona Savignyi  Polypeptide  Purification And Identification  
A novel polypeptide from Meretrix meretrix Linnaeus inhibits the growth of human lung adenocarcinoma 期刊论文
EXPERIMENTAL BIOLOGY AND MEDICINE, 2012, 卷号: 237, 期号: 4, 页码: 442-450
作者:  Wang, Cuicui;  Liu, Ming;  Cheng, Linyou;  Wei, Jianteng;  Wu, Ning;  Zheng, Lanhong;  Lin, Xiukun;  Lin, XK (reprint author), Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China.
Adobe PDF(697Kb)  |  收藏  |  浏览/下载:350/0  |  提交时间:2013/09/24
Meretrix Meretrix Linnaeus  Antitumor Polypeptide  Non-small-cell Lung Carcinoma  g(2)/m Phase Arrest  Apoptosis  
一种玻璃海鞘多肽及其制备 专利
专利类型: 发明, 专利号: CN201010620668.8, 申请日期: 2011-09-07, 公开日期: 2011-09-07
发明人:  林秀坤;  程林友;  魏建腾;  郑兰红;  王翠翠
Adobe PDF(651Kb)  |  收藏  |  浏览/下载:308/0  |  提交时间:2014/08/04
一种玻璃海鞘多肽  其特征在于:玻璃海鞘多肽n?末端序列为yqpdkfmlrgelrnn  分子量为5931da  等电点为7.25。