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IOCAS-IR

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Discovery of 5-(3-bromo-2-(2,3-dibromo-4,5-dimethoxybenzyl)-4,5-dimethoxybenzylidene)thiazolidine-2,4-dione as a novel potent protein tyrosine phosphatase 1B inhibitor with antidiabetic properties 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 108, 页码: 13
作者:  Jiang, Bo;  Luo, Jiao;  Guo, Shuju;  Wang, Lijun
Adobe PDF(8153Kb)  |  收藏  |  浏览/下载：254/0  |  提交时间：2021/05/11
Type 2 diabetes mellitus  Protein tyrosine phosphatase 1B inhibitors  Thiazolidinedione  Insulin signaling  Anti-diabetic activities  
The Involvement of the Mammalian Target of Rapamycin, Protein Tyrosine Phosphatase 1b and Dipeptidase 4 Signaling Pathways in Cancer and Diabetes: A Narrative Review 期刊论文
MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2021, 卷号: 21, 期号: 7, 页码: 803-815
作者:  Zhang, Jiajia;  Wu, Ning;  Shi, Dayong
Adobe PDF(1363Kb)  |  收藏  |  浏览/下载：414/0  |  提交时间：2021/05/11
Signaling pathway  mammalian target of rapamycin  protein tyrosine phosphatase 1b  dipeptidase 4  cancer  diabetes  pharmacology  target compounds  
Highly Selective Protein Tyrosine Phosphatase Inhibitor, 2,2 ',3,3 '-Tetrabromo-4,4 ',5,5 '-tetrahydroxydiphenylmethane, Ameliorates Type 2 Diabetes Mellitus in BKS db Mice 期刊论文
MOLECULAR PHARMACEUTICS, 2019, 卷号: 16, 期号: 5, 页码: 1839-1850
作者:  Li, Chao;  Luo, Jiao;  Guo, Shuju;  Jia, Xiaoling;  Guo, Chuanlong;  Li, Xiangqian;  Xu, Qi;  Shi, Dayong
收藏  |  浏览/下载：445/0  |  提交时间：2019/08/28
type 2 diabetes mellitus  protein tyrosine phosphatase 1B  insulin resistance  hypoglycemic activity  dyslipidemia  
Association and Functional Analyses Revealed That PPP1R3B Plays an Important Role in the Regulation of Glycogen Content in the Pacific Oyster Crassostrea gigas 期刊论文
FRONTIERS IN GENETICS, 2019, 卷号: 10, 页码: 16
作者:  Liu, Sheng;  Li, Li;  Meng, Jie;  Song, Kai;  Huang, Baoyu;  Wang, Wei;  Zhang, Guofan
Adobe PDF(4903Kb)  |  收藏  |  浏览/下载：305/0  |  提交时间：2019/05/15
oyster  glycogen content  protein phosphatase 1 regulatory subunit 3B (PPP1R3B)  gene function analyses  associated SNPs  
BPN, a marine-derived PTP1B inhibitor, activates insulin signaling and improves insulin resistance in C2C12 myotubes 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2018, 卷号: 106, 页码: 379-386
作者:  Xu, Qi;  Luo, Jiao;  Wu, Ning;  Zhang, Renshuai;  Shi, Dayong
Adobe PDF(1900Kb)  |  收藏  |  浏览/下载：268/0  |  提交时间：2018/04/02
Bpn  Protein Tyrosine Phosphatase 1b  Insulin Signaling  Insulin Resistance  C2c12 Myotubes  
Chrodrimanins O-S from the fungus Penicillium. sp SCS-KFD09 isolated from a marine worm, Sipunculusnudus 期刊论文
FITOTERAPIA, 2017, 卷号: 122, 页码: 1-6
作者:  Kong, Fan-Dong;  Zhang, Ren-Shuai;  Ma, Qing-Yun;  Xie, Qing-Yi;  Wang, Pei;  Chen, Peng-Wei;  Zhou, Li-Man;  Dai, Hao-Fu;  Luo, Du-Qiang;  Zhao, You-Xing
Adobe PDF(681Kb)  |  收藏  |  浏览/下载：299/0  |  提交时间：2018/01/11
Penicillitun Sp.  Chrodrimanins  Fungus  Protein Tyrosine Phosphatase 1b Inhibition  
Discovery of novel bromophenol 3,4-dibromo-5-(2-bromo-3,4-dihydroxy-6-(isobutoxymethyl)benzyl)benzene-1,2-diol as protein tyrosine phosphatase 1B inhibitor and its anti-diabetic properties in C57BL/KsJ-db/db mice 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2013, 卷号: 64, 页码: 129-136
作者:  Jiang, Bo;  Guo, Shuju;  Shi, Dayong;  Guo, Chao;  Wang, Tao;  Shi, DY
Adobe PDF(1213Kb)  |  收藏  |  浏览/下载：387/1  |  提交时间：2014/07/17
Type 2 Diabetes Mellitus  Protein Tyrosine Phosphatase 1b  Bromophenol  Anti-diabetic Activities  
SmLMWPTP, a teleost low molecular weight protein tyrosine phosphatase, inhibits the immune response of peripheral blood leukocytes in a manner that depends on the conserved P-loop 期刊论文
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY, 2013, 卷号: 40, 期号: 2, 页码: 103-111
作者:  Zhang, Jian;  Chen, Ling;  Sun, Li;  Sun, L
Adobe PDF(1911Kb)  |  收藏  |  浏览/下载：302/0  |  提交时间：2014/07/17
Protein Tyrosine Phosphatase  Scophthalmus Maximus  Immune Regulation  Phagocytosis  
HPN, a Synthetic Analogue of Bromophenol from Red Alga Rhodomela confervoides: Synthesis and Anti-Diabetic Effects in C57BL/KsJ-db/db Mice 期刊论文
MARINE DRUGS, 2013, 卷号: 11, 期号: 2, 页码: 350-362
作者:  Shi, Dayong;  Guo, Shuju;  Jiang, Bo;  Guo, Chao;  Wang, Tao;  Zhang, Luyong;  Li, Jingya;  Shi, DY
Adobe PDF(662Kb)  |  收藏  |  浏览/下载：334/0  |  提交时间：2014/07/17
Bromophenol  Protein Tyrosine Phosphatase 1b Inhibitor  Db/db Mouse Model  Anti-diabetes Properties  
Characterization of the protein phosphatase 2c gene from Porphyra yezoensis and functional analysis under dessicating conditions 期刊论文
BOTANICA MARINA, 2012, 卷号: 55, 期号: 4, 页码: 427-434
作者:  Zhang, Bao Yu;  Jia, Zhao Jun;  He, Lin Wen;  Wang, Guang Ce;  Peng, Guang;  Wang, GC (reprint author), Chinese Acad Sci, Key Lab Expt Marine Biol, Inst Oceanol, Qingdao 266071, Peoples R China.
Adobe PDF(1031Kb)  |  收藏  |  浏览/下载：303/0  |  提交时间：2013/09/24
Desiccation  Mrna Expression Level  Porphyra Yezoensis  Protein Phosphatase 2c Gene  Qpcr