The role of the balance between energy production and ammonia detoxification mediated by key amino acids in divergent hypersaline adaptation among crassostrea oysters

doi:10.1016/j.envres.2024.118213

IOCAS-IR > 实验海洋生物学重点实验室

	The role of the balance between energy production and ammonia detoxification mediated by key amino acids in divergent hypersaline adaptation among crassostrea oysters
	Zhao, Mingjie 1,4; Li, Ao 1,2,3,5,9; Zhang, Kexin 1,4; Wang, Wei 1,6; Zhang, Guofan 1,2,3,5,6; Li, Li 1,3,4,5,6,7,8
	2024-05-01
发表期刊	ENVIRONMENTAL RESEARCH
ISSN	0013-9351
卷号	248 页码:10
通讯作者	Li, Ao([email protected]) ; Li, Li([email protected])
摘要	Global ocean salinity is changing under rapid climate change and intensified anthropogenic activity. Increased differences in salinity threaten marine biodiversity, organismal survival, and evolution, particularly sessile invertebrates dwelling in highly fluctuating intertidal and estuarine environments. Comparing the responses of closely related species to salinity changes can provide insights into the adaptive mechanisms underlying interand intraspecific divergence in salinity tolerance, but are poorly understood in marine bivalves. We collected wild individuals of four Crassostrea species, in addition to two populations of the same species from their native habitats and determined the dynamics of hydrolyzed amino acids (HAAs) and transcriptional responses to hypersaline stress. In response to hypersaline stress, species/populations inhabiting natural high-salinity sea environments showed higher survival and less decline in HAAs than that of congeners inhabiting low-salinity estuaries. Thus, native environmental salinity shapes oyster tolerance. Notably, a strong negative correlation between the decline in HAAs and survival indicated that the HAAs pool could predict tolerance to hypersaline challenge. Four HAAs, including glutamine (Glu), aspartic acid (Asp), alanine (Ala) and glycine (Gly), were identified as key amino acids that contributed substantially to the emergency response to hypersaline stress. High-salinity-adapted oyster species only induced substantial decreases in Glu and Asp, whereas low-salinityadapted congeners further incresaed Ala and Gly metabolism under hypersaline stress. The dynamics of the content and gene expression responsible for key amino acids pathways revealed the importance of maintaining the balance between energy production and ammonia detoxification in divergent hypersaline responses among oyster species/populations. High constructive or plastic expression of evolutionarily expanded gene copies in high-salinity-adapted species may contribute to their greater hypersaline tolerance. Our findings reveal the adaptive mechanism of key amino acids in salinity adaptation in marine bivalves and provide new avenues for the prediction of adaptive potential and aquaculture with high-salinity tolerant germplasms.
关键词	Environmental change Salinity adaptation Crassostrea oysters Key amino acids Energy production Ammonia detoxification
DOI	10.1016/j.envres.2024.118213
收录类别	SCI
语种	英语
资助项目	Key Research and Development Program of Shandong[ZFJH202309]; Youth Innovation Promotion Association, Chinese Academy of Sciences[2023215]; Young Elite Scientists Sponsorship Program by the China Association for Science and Technology[2021QNRC001]; National Natural Science Foundation of China[32101353]; National Key Research and Development Program of China[2022YFD2400304]; Earmarked fund for CAR[CARS -49]
WOS研究方向	Environmental Sciences & Ecology ; Public, Environmental & Occupational Health
WOS类目	Environmental Sciences ; Public, Environmental & Occupational Health
WOS记录号	WOS:001181726200001
出版者	ACADEMIC PRESS INC ELSEVIER SCIENCE
WOS关键词	MYTILUS-EDULIS ; ISKENDERUN BAY ; OXIDATIVE STRESS ; SALINITY CHANGE ; RANGIA-CUNEATA ; HEAVY-METALS ; HEART-RATE ; METABOLISM ; CLASSIFICATION ; COASTAL
引用统计	被引频次：1[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.qdio.ac.cn/handle/337002/184876
专题	实验海洋生物学重点实验室
通讯作者	Li, Ao; Li, Li
作者单位	1.Chinese Acad Sci, Inst Oceanol, Ctr Ocean Mega Sci, CAS & Shandong Prov Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China 2.Laoshan Lab, Lab Marine Biol & Biotechnol, Qingdao 266237, Peoples R China 3.Chinese Acad Sci, Key Lab Breeding Biotechnol & Sustainable Aquacult, Wuhan 430072, Peoples R China 4.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 5.Southern Marine Sci & Engn Guangdong Lab Zhanjiang, Zhanjiang 524000, Peoples R China 6.Chinese Acad Sci, Inst Oceanol, Natl & Local Joint Engn Lab Ecol Mariculture, Qingdao 266071, Peoples R China 7.Shandong Technol Innovat Ctr Oyster Seed Ind, Qingdao 266000, Peoples R China 8.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao, Shandong, Peoples R China 9.Chinese Acad Sci, Inst Oceanol, Lab Expt Marine Biol, Qingdao 266071, Peoples R China
第一作者单位	中国科学院海洋研究所
通讯作者单位	中国科学院海洋研究所
推荐引用方式 GB/T 7714	Zhao, Mingjie,Li, Ao,Zhang, Kexin,et al. The role of the balance between energy production and ammonia detoxification mediated by key amino acids in divergent hypersaline adaptation among crassostrea oysters[J]. ENVIRONMENTAL RESEARCH,2024,248:10.
APA	Zhao, Mingjie,Li, Ao,Zhang, Kexin,Wang, Wei,Zhang, Guofan,&Li, Li.(2024).The role of the balance between energy production and ammonia detoxification mediated by key amino acids in divergent hypersaline adaptation among crassostrea oysters.ENVIRONMENTAL RESEARCH,248,10.
MLA	Zhao, Mingjie,et al."The role of the balance between energy production and ammonia detoxification mediated by key amino acids in divergent hypersaline adaptation among crassostrea oysters".ENVIRONMENTAL RESEARCH 248(2024):10.