Secondary Metabolites with Agricultural Antagonistic Potentials from Beauveria felina, a Marine-Derived Entomopathogenic Fungus

doi:10.1021/acs.jafc.0c05696

IOCAS-IR > 实验海洋生物学重点实验室

	Secondary Metabolites with Agricultural Antagonistic Potentials from Beauveria felina, a Marine-Derived Entomopathogenic Fungus
	Du, Feng-Yu 1,2,3; Li, Xiao-Ming 2,3; Sun, Ze-Chun 4; Meng, Ling-Hong2,3 ; Wang, Bin-Gui2,3,5
	2020-12-16
发表期刊	JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
ISSN	0021-8561
卷号	68 期号:50 页码:14824-14831
通讯作者	Wang, Bin-Gui([email protected])
摘要	Soil-borne pathogens and weeds could synergistically affect vegetable growth and result in serious losses. The investigation of antagonistic metabolites from a marine-derived entomopathogenic fungus, Beauveria felina, obtained polyhydroxy steroid (1), tricyclic diterpenoid (2), isaridin (3), and destruxin cyclodepsipeptides (4-6). The structures and absolute configurations of new 1-3 were elucidated by extensive spectroscopic and X-ray crystallographic analyses, as well as electronic circular dichroism (ECD) calculations. Compounds 1 and 2 showed antifungal activities against carbendazim-resistant strains of Botrytis cinerea, with the minimum inhibitory concentration (MIC) values ranging from 16 to 32 mu g/mL, which were significantly better than those of carbendazim (MIC = 256 mu g/mL). Compound 5 exhibited significant antagonistic activity against the radicle growth of Amaranthus retroflexus seedlings, which was almost identical to that of the positive control (2,4-dichlorophenoxyacetic acid). The structure-activity differences of 4-6 suggested that the CI atom in HMPA(1) and beta-Me in Pro(2) should be the key factors to their herbicidal activities. Besides, compounds 3-6 showed moderate nematicidal activities against Meloidogyne incognita. These antagonistic effects of 1-6 were first reported and further revealed the synergistically antagonistic potential of B. felina to be developed into the biopesticide.
关键词	Beauveria felina agricultural antagonistic potential secondary metabolites antifungal activity herbicidal activity
DOI	10.1021/acs.jafc.0c05696
收录类别	SCI
语种	英语
资助项目	Natural Science Foundation of China[31270104]; NSFCShandong Joint Fund for Marine Science Research Centers[U1606403]; Taishan Scholar project from Shandong province[ts201511060]
WOS研究方向	Agriculture ; Chemistry ; Food Science & Technology
WOS类目	Agriculture, Multidisciplinary ; Chemistry, Applied ; Food Science & Technology
WOS记录号	WOS:000600204700010
出版者	AMER CHEMICAL SOC
引用统计	被引频次：22[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.qdio.ac.cn/handle/337002/169496
专题	实验海洋生物学重点实验室
通讯作者	Wang, Bin-Gui
作者单位	1.Qingdao Agr Univ, Coll Chem & Pharmaceut Sci, Qingdao 266109, Peoples R China 2.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China 3.Chinese Acad Sci, Qingdao Natl Lab Marine Sci & Technol, Lab Marine Biol & Biotechnol, Qingdao 266071, Peoples R China 4.Qingdao Agr Univ, Coll Chem & Pharm, Qingdao 266109, Peoples R China 5.Chinese Acad Sci, Ctr Ocean Megasci, Qingdao 266071, Peoples R China
推荐引用方式 GB/T 7714	Du, Feng-Yu,Li, Xiao-Ming,Sun, Ze-Chun,et al. Secondary Metabolites with Agricultural Antagonistic Potentials from Beauveria felina, a Marine-Derived Entomopathogenic Fungus[J]. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,2020,68(50):14824-14831.
APA	Du, Feng-Yu,Li, Xiao-Ming,Sun, Ze-Chun,Meng, Ling-Hong,&Wang, Bin-Gui.(2020).Secondary Metabolites with Agricultural Antagonistic Potentials from Beauveria felina, a Marine-Derived Entomopathogenic Fungus.JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,68(50),14824-14831.
MLA	Du, Feng-Yu,et al."Secondary Metabolites with Agricultural Antagonistic Potentials from Beauveria felina, a Marine-Derived Entomopathogenic Fungus".JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 68.50(2020):14824-14831.

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