Halogenated Compounds from Corals: Chemical Diversity and Biological Activities

doi:10.2174/1389557518666181113124015

IOCAS-IR > 实验海洋生物学重点实验室

	Halogenated Compounds from Corals: Chemical Diversity and Biological Activities
	Zhang, Yuanyuan 1; Liu, Junhong 1; Shi, Dayong 2,3; Li, Zheng 1
	2019
发表期刊	MINI-REVIEWS IN MEDICINAL CHEMISTRY
ISSN	1389-5575
卷号	19 期号:15 页码:1204-1218
通讯作者	Liu, Junhong([email protected]) ; Shi, Dayong([email protected])
摘要	As important marine biological resources, corals produce a large amount of active organic compounds in their secondary metabolic processes, including numerous brominated, chlorinated, and iodinated compounds. These compounds, with novel structures and unique activities, guide the discovery and research of important lead compounds and novel biological mechanisms. Through a large number of literature surveys, this paper summarized a total of 145 halogenated secondary metabolites which were roughly divided into four major classes of terpenes, prostaglandins, steroids and alkaloids, and they were mainly isolated from ten coral families, Ellisellidae, Gorgoniidae, Briareidae, Plexauridae, Anthothelidae, Alcyoniidae, Clavularidae, Tubiporidae, Nephtheidae and Dendrophyllidae to the best of our knowledge. In addition, their organism species, structure composition and biological activity were also discussed in the form of a chart in this essay.
关键词	Marine corals metabolites halogenated bioactivity chemical diversity
DOI	10.2174/1389557518666181113124015
收录类别	SCI
语种	英语
资助项目	National Natural Science Foundation of China[81773586]; National Natural Science Foundation of China[81703354]; Key research and development project of Shandong province[2016GSF201193]; Key research and development project of Shandong province[2016ZDJS07A13]; Key research and development project of Shandong province[2016GSF115002]; Key research and development project of Shandong province[2016GSF115009]; CAS[QYZDB-SSW-DQC014]; Project of Discovery, Evaluation and Transformation of Active Natural Compounds, Strategic Biological Resources Service Network Programme of Chinese Academy of Sciences[ZSTH026]; Shandong Provincial Natural Science Foundation for Distinguished Young Scholars[JQ201722]; National Program for Support of Top-notch Young Professionals; Taishan scholar Youth Project of Shandong province
WOS研究方向	Pharmacology & Pharmacy
WOS类目	Chemistry, Medicinal
WOS记录号	WOS:000493818600002
出版者	BENTHAM SCIENCE PUBL LTD
引用统计	被引频次：3[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.qdio.ac.cn/handle/337002/164827
专题	实验海洋生物学重点实验室
通讯作者	Liu, Junhong; Shi, Dayong
作者单位	1.Qingdao Univ Sci & Technol, Dept Pharmaceut, Qingdao 266042, Shandong, Peoples R China 2.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao 266071, Shandong, Peoples R China 3.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Biol & Biotechnol, Qingdao 266071, Shandong, Peoples R China
通讯作者单位	中国科学院海洋研究所
推荐引用方式 GB/T 7714	Zhang, Yuanyuan,Liu, Junhong,Shi, Dayong,et al. Halogenated Compounds from Corals: Chemical Diversity and Biological Activities[J]. MINI-REVIEWS IN MEDICINAL CHEMISTRY,2019,19(15):1204-1218.
APA	Zhang, Yuanyuan,Liu, Junhong,Shi, Dayong,&Li, Zheng.(2019).Halogenated Compounds from Corals: Chemical Diversity and Biological Activities.MINI-REVIEWS IN MEDICINAL CHEMISTRY,19(15),1204-1218.
MLA	Zhang, Yuanyuan,et al."Halogenated Compounds from Corals: Chemical Diversity and Biological Activities".MINI-REVIEWS IN MEDICINAL CHEMISTRY 19.15(2019):1204-1218.