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中国科学院海洋研究所机构知识库
Knowledge Management System Of Institute of Oceanology, Chinese Academy of Sciences
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The ERK-MNK-eIF4F signaling pathway mediates TPDHT-induced A549 cell death in vitro and in vivo
期刊论文
FOOD AND CHEMICAL TOXICOLOGY, 2020, 卷号: 137, 页码: 10
作者:
Guo, Chuanlong
;
Hou, Yuzhen
;
Yu, Xuemin
;
Zhang, Fan
;
Wu, Xiaochen
;
Wu, Xianggen
;
Wang, Lijun
Adobe PDF(2640Kb)
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浏览/下载:248/0
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提交时间:2020/09/22
Apoptosis
eIF4F
ERK
MNK
A549 cells
The Fluoro-Thiazolylhydrazone Compound TSC-3C Inhibits Triple Negative Breast Cancer (TNBC) Cell Line Activity by Promoting Apoptosis, Regulating the MAPK Pathway and Inducing Mitochondrial Dysfunction
期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2020, 卷号: 21, 期号: 3, 页码: 15
作者:
Zhang, Jiajia
;
Dai, Jiajia
;
Zheng, Qingxuan
;
Guo, Shuju
;
Yu, Yanyan
;
Hu, Wenpeng
;
Gao, Yanan
;
Shi, Dayong
Adobe PDF(2858Kb)
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浏览/下载:268/0
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提交时间:2020/09/23
triple negative breast cancer
MDA-MB-231 cells
fluoro-thiazolylhydrazone
MAPK pathway
phosphorylated p44/42 MAPK (ERK1/2)
phosphorylated c-Jun N-terminal kinase (p-JNK)
apoptosis
Dietary beta-glucan modulate haematological parameters, cytokines and gene expression in TLR and ERK pathways of rainbow trout (Oncorhynchus mykiss) during infection by Aeromonas salmonicida
期刊论文
AQUACULTURE RESEARCH, 2019, 页码: 12
作者:
Ji, Liqin
;
Fu, Songzhe
;
Sun, Guoxiang
;
Li, Xian
;
Liu, Ying
Adobe PDF(1766Kb)
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浏览/下载:469/0
  |  
提交时间:2020/03/20
Aeromonas salmonicida
cytokines
rainbow trout
TLR and ERK signalling pathways
beta-glucans
Hydroxypropyltrimethyl ammonium chloride chitosan activates RAW 264.7 macrophages through the MAPK and JAK-STAT signaling pathways
期刊论文
CARBOHYDRATE POLYMERS, 2019, 卷号: 205, 页码: 401-409
作者:
Yang, Yue
;
Xing, Ronge
;
Liu, Song
;
Qin, Yukun
;
Li, Kecheng
;
Yu, Huahua
;
Li, Pengcheng
Adobe PDF(1085Kb)
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浏览/下载:223/0
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提交时间:2019/05/15
Hydroxypropyltrimethyl ammonium chloride
chitosan
Immunostimulatory activity
ERK
JNK
P38
STAT
A Novel Bromophenol Derivative BOS-102 Induces Cell Cycle Arrest and Apoptosis in Human A549 Lung Cancer Cells via ROS-Mediated PI3K/Akt and the MAPK Signaling Pathway
期刊论文
MARINE DRUGS, 2018, 卷号: 16, 期号: 2, 页码: 13
作者:
Guo, Chuan-Long
;
Wang, Li-Jun
;
Zhao, Yue
;
Liu, Hua
;
Li, Xiang-Qian
;
Jiang, Bo
;
Luo, Jiao
;
Guo, Shu-Ju
;
Wu, Ning
;
Shi, Da-Yong
Adobe PDF(5208Kb)
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浏览/下载:438/0
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提交时间:2019/08/21
bromophenol
molecular mechanisms
apoptosis
cell cycle
PI3K
Akt
p38
ERK
ROS
human lung cancer
Wentilactone A as a novel potential antitumor agent induces apoptosis and G2/M arrest of human lung carcinoma cells, and is mediated by HRas-GTP accumulation to excessively activate the Ras/Raf/ERK/p53-p21 pathway
期刊论文
CELL DEATH & DISEASE, 2013, 卷号: 4, 页码: e952
作者:
Lv, C.
;
Hong, Y.
;
Miao, L.
;
Li, C.
;
Xu, G.
;
Wei, S.
;
Wang, B.
;
Huang, C.
;
Jiao, B.
;
Wang, B
Adobe PDF(3582Kb)
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浏览/下载:366/0
  |  
提交时间:2014/07/17
Wentilactone a
Novel Antitumor Agent
Lung Cancer
Ras/raf/erk/p53-p21 Pathway
Asperolide A, a Marine-Derived Tetranorditerpenoid, Induces G2/M Arrest in Human NCI-H460 Lung Carcinoma Cells, Is Mediated by p53-p21 Stabilization and Modulated by Ras/Raf/MEK/ERK Signaling Pathway
期刊论文
MARINE DRUGS, 2013, 卷号: 11, 期号: 2, 页码: 316-331
作者:
Lv, Cuiting
;
Sun, Wenxia
;
Sun, Haofen
;
Wei, Shanjian
;
Chen, Ruohua
;
Wang, Bingui
;
Huang, Caiguo
;
Chen, RH
Adobe PDF(1126Kb)
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浏览/下载:476/0
  |  
提交时间:2014/07/17
Asperolide a
G2/m Arrest
P53-p21
Ras/raf/mek/erk Signaling Pathway
SD118-Xanthocillin X (1), a Novel Marine Agent Extracted from Penicillium commune, Induces Autophagy through the Inhibition of the MEK/ERK Pathway
期刊论文
MARINE DRUGS, 2012, 卷号: 10, 期号: 6, 页码: 1345-1359
作者:
Zhao, Ying
;
Chen, Huan
;
Shang, Zhuo
;
Jiao, Binghua
;
Yuan, Bin
;
Sun, Weizhang
;
Wang, Bingui
;
Miao, Mingyong
;
Huang, Caiguo
;
Wang, BG (reprint author), Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China.
Adobe PDF(1776Kb)
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浏览/下载:403/0
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提交时间:2013/09/24
Sd118-xanthocillin x (1)
Autophagy
Apoptosis
Erk
Beclin 1