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Mixed micelles loaded with hesperidin protect against acetaminophen induced acute liver injury by inhibiting the mtDNA-cGAS-STING pathway 期刊论文
COLLOIDS AND SURFACES B-BIOINTERFACES, 2024, 卷号: 233, 页码: 12
作者:  Dong, Kehong;  Sun, Yuxuan;  Gao, Xintao;  Wang, Jing;  Wu, Xiaochen;  Guo, Chuanlong
收藏  |  浏览/下载：22/0  |  提交时间：2024/04/07
Acetaminophen  Liver injury  Hesperidin  MtDNA  CGAS-STING  
Silk fibroin peptide self-assembled nanofibers delivered naringenin to alleviate cisplatin-induced acute kidney injury by inhibiting mtDNA-cGAS-STING pathway 期刊论文
FOOD AND CHEMICAL TOXICOLOGY, 2023, 卷号: 177, 页码: 10
作者:  Liu, Shuai;  Gao, Xintao;  Yin, Yulan;  Wang, Jing;  Dong, Kehong;  Shi, Dayong;  Wu, Xiaochen;  Guo, Chuanlong
收藏  |  浏览/下载：209/0  |  提交时间：2023/12/13
Silk fibroin peptide  Naringin  Acute kidney injury  Mitophagy  cGAS-STING pathway  
EGPI-1, a novel eIF4E/eIF4G interaction inhibitor, inhibits lung cancer cell growth and angiogenesis through Ras/MNK/ERK/eIF4E signaling pathway 期刊论文
CHEMICO-BIOLOGICAL INTERACTIONS, 2022, 卷号: 352, 页码: 10
作者:  Qi, Xueju;  Zhang, Shuna;  Chen, Zekun;  Wang, Lijun;  Zhu, Wenyong;  Yin, Chuanjin;  Fan, Junting;  Wu, Xiaochen;  Wang, Jing;  Guo, Chuanlong
Adobe PDF(10635Kb)  |  收藏  |  浏览/下载：224/0  |  提交时间：2022/07/18
Human lung cancer  eIF4E  EGPI-1  Anticancer  Angiogenesis  
Novel poly (ADP-ribose) polymerases inhibitor DHC-1 exhibits in vitro and in vivo anticancer activity on BRCA-deficient pancreatic cancer cells 期刊论文
FOOD AND CHEMICAL TOXICOLOGY, 2021, 卷号: 147, 页码: 10
作者:  Wu, Xiaochen;  Li, Qiqi;  Zhang, Fan;  Wang, Lijun;  Wang, Jun;  Fan, Junting;  Di, Guohu;  Guo, Chuanlong
Adobe PDF(8144Kb)  |  收藏  |  浏览/下载：252/0  |  提交时间：2021/04/21
PARP inhibitor  BRCA  Pancreatic cancer  
BTH-8, a novel poly (ADP-ribose) polymerase-1 (PARP-1) inhibitor, causes DNA double-strand breaks and exhibits anticancer activities in vitro and in vivo 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2020, 卷号: 150, 页码: 238-245
作者:  Guo, Chuanlong;  Zhang, Fan;  Wu, Xiaochen;  Yu, Xuemin;  Wu, Xianggen;  Shi, Dayong;  Wang, Lijun
Adobe PDF(1767Kb)  |  收藏  |  浏览/下载：272/0  |  提交时间：2020/09/23
PARP-1 inhibitor  DNA double-strand breaks  HCC-1937  In vivo  Apoptosis  
The ERK-MNK-eIF4F signaling pathway mediates TPDHT-induced A549 cell death in vitro and in vivo 期刊论文
FOOD AND CHEMICAL TOXICOLOGY, 2020, 卷号: 137, 页码: 10
作者:  Guo, Chuanlong;  Hou, Yuzhen;  Yu, Xuemin;  Zhang, Fan;  Wu, Xiaochen;  Wu, Xianggen;  Wang, Lijun
Adobe PDF(2640Kb)  |  收藏  |  浏览/下载：248/0  |  提交时间：2020/09/22
Apoptosis  eIF4F  ERK  MNK  A549 cells