IOCAS-IR

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Catalytic site flexibility facilitates the substrate and catalytic promiscuity of Vibrio dual lipase/transferase 期刊论文
NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 11
作者:  Wang, Chongyang;  Liu, Changshui;  Zhu, Xiaochuan;  Peng, Quancai;  Ma, Qingjun
收藏  |  浏览/下载:123/0  |  提交时间:2023/12/13
Lysine acetylation of Escherichia coli lactate dehydrogenase regulates enzyme activity and lactate synthesis 期刊论文
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, 2022, 卷号: 10, 页码: 12
作者:  Liu, Min;  Huo, Meitong;  Liu, Changshui;  Guo, Likun;  Ding, Yamei;  Ma, Qingjun;  Qi, Qingsheng;  Xian, Mo;  Zhao, Guang
收藏  |  浏览/下载:200/0  |  提交时间:2023/01/12
lysine acetylation  lactate dehydrogenase A  enzyme activity  metabolic engineering  lactate synthesis  
Structural basis of staphylococcal Stl inhibition on a eukaryotic dUTPase 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2021, 卷号: 184, 页码: 821-830
作者:  Wang, Fang;  Liu, Changshui;  Wang, Chongyang;  Wang, Yan;  Zang, Kun;  Wang, Xin;  Liu, Xiaohua;  Li, Shihao;  Li, Fuhua;  Ma, Qingjun
Adobe PDF(2684Kb)  |  收藏  |  浏览/下载:303/0  |  提交时间:2021/09/18
Stl dUTPase interactions  Proteinaceous inhibitor  Crystal structure  
Structural analysis of the CARB beta-lactamase from Vibrio parahaemolyticus facilitates application of the beta-lactam/beta-lactamase inhibitor therapy 期刊论文
BIOCHIMIE, 2020, 卷号: 171, 页码: 213-222
作者:  Li, Peihai;  Liu, Changshui;  Li, Baojie;  Ma, Qingjun
Adobe PDF(2557Kb)  |  收藏  |  浏览/下载:228/0  |  提交时间:2020/09/23
Vibrio parahaemolyticus  CARB beta-lactamase  CARB-17 family  Directed evolution  Inhibitor resistance  
Structural analysis of a shrimp thymidylate synthase reveals species-specific interactions with dUMP and raltitrexed 期刊论文
JOURNAL OF OCEANOLOGY AND LIMNOLOGY, 2020, 页码: 9
作者:  Liu Changshui;  Zang Kun;  Li Shihao;  Li Fuhua;  Ma Qingiun
Adobe PDF(1545Kb)  |  收藏  |  浏览/下载:210/0  |  提交时间:2020/09/22
thymidylate synthase (TS)  closed conformation  deoxyuridine monophosphate (dUMP)  thymidine monophosphate (TMP)  raltitrexed  Litopenaeus vannamei  
Structural basis for specific calcium binding by the polycystic-kidney-disease domain of Vibrio anguillarum protease Epp 期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2018, 卷号: 505, 期号: 2, 页码: 471-477
作者:  Li, Peihai;  Zang, Kun;  Li, Yingjie;  Liu, Changshui;  Ma, Qingjun
Adobe PDF(1786Kb)  |  收藏  |  浏览/下载:286/0  |  提交时间:2019/05/15
Vibrio anguillarum  Polycystic-kidney-disease domain  Protease maturation  Ca2+-binding site  Protein stability  
The putative siderophore-interacting protein from Vibrio anguillarum: protein production, analysis, crystallization and X-ray crystallographic studies 期刊论文
ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS, 2018, 卷号: 74, 页码: 283-287
作者:  Han, Yu;  Zang, Kun;  Liu, Changshui;  Li, Yingjie;  Ma, Qingjun
Adobe PDF(193Kb)  |  收藏  |  浏览/下载:335/0  |  提交时间:2019/08/21
Vibrio anguillarum  siderophore-interacting proteins  iron release  siderophores  
Structural and enzymatic analysis of the cytochrome b(5) reductase domain of Ulva prolifera nitrate reductase 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2018, 卷号: 111, 页码: 1175-1182
作者:  You, Cai;  Liu, Changshui;  Li, Yingjie;  Jiang, Peng;  Ma, Qingjun
Adobe PDF(3475Kb)  |  收藏  |  浏览/下载:349/0  |  提交时间:2019/08/21
Ulva prolifera  Nitrate reductase  Indel  Cytochrome b(5) reductase  
Malonyl-CoA pathway: a promising route for 3-hydroxypropionate biosynthesis 期刊论文
CRITICAL REVIEWS IN BIOTECHNOLOGY, 2017, 卷号: 37, 期号: 7, 页码: 933-941
作者:  Liu, Changshui;  Ding, Yamei;  Xian, Mo;  Liu, Min;  Liu, Huizhou;  Ma, Qingjun;  Zhao, Guang
Adobe PDF(1463Kb)  |  收藏  |  浏览/下载:330/0  |  提交时间:2018/01/11
3-hydroxypropionate  Malonyl-coa Pathway  Metabolic Engineering  Acetyl-coa Carboxylase  Malonyl-coa Reductase  Carbon Flux  Enzyme Engineering  Supply Of Energy And cOfactor  3hp Tolerance  
Functional balance between enzymes in malonyl-CoA pathway for 3-hydroxypropionate biosynthesis 期刊论文
METABOLIC ENGINEERING, 2016, 卷号: 34, 期号: 2016, 页码: 104-111
作者:  Liu, Changshui;  Ding, Yamei;  Zhang, Rubing;  Liu, Huizhou;  Xian, Mo;  Zhao, Guang
Adobe PDF(1232Kb)  |  收藏  |  浏览/下载:294/0  |  提交时间:2016/05/03
3-hydroxypropionate  Malonyl-coa Pathway  Malonyl-coa Reductase  Enzymatic Activity Imbalance  RE.ombinant E. Coli