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Depositional control on the fate of reactive iron in shelf sediments since the last deglaciation: A case study of the East China Sea 期刊论文
MARINE GEOLOGY, 2024, 卷号: 475, 页码: 13
作者:  Kong, Fanxing;  Liu, Xiting;  Li, Anchun;  Dong, Jiang;  Wang, Houjie;  Zhuang, Guangchao;  Zhang, Zihu;  Li, Chao
收藏  |  浏览/下载:51/0  |  提交时间:2024/09/02
Reactive iron  Depositional environment  Redox state  Source-sink  East China Sea  
海蜇蛋白肽的制备及其抗氧化和美白活性研究 学位论文
, 中国科学院海洋研究所: 中国科学院海洋研究所, 2023
作者:  滕李超
Adobe PDF(3223Kb)  |  收藏  |  浏览/下载:82/0  |  提交时间:2023/06/21
Antidiabetic activity in vitro and in vivo of BDB, a selective inhibitor of protein tyrosine phosphatase 1B, fromRhodomela confervoides 期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2020, 卷号: 177, 期号: 19, 页码: 4464-4480
作者:  Luo, Jiao;  Zheng, Meiling;  Jiang, Bo;  Li, Chao;  Guo, Shuju;  Wang, Lijun;  Li, Xiangqian;  Yu, Rilei;  Shi, Dayong
Adobe PDF(42653Kb)  |  收藏  |  浏览/下载:421/0  |  提交时间:2020/09/29
bromophenol  PTP1B inhibitor  selectivity  cell permeability  oral bioavailability  
An UHPLC-TOF-MS method for quantifying novel brominated anticancer compound bromophenol-thiosemicarbazone hybrid and its application to in vivo pharmacokinetic study 期刊论文
JOURNAL OF ANALYTICAL SCIENCE AND TECHNOLOGY, 2020, 卷号: 11, 期号: 1, 页码: 7
作者:  Li, Xiuxue;  Wang, Lijun;  Jia, Xiaoling;  Guo, Chuanlong;  Li, Chao;  Zhang, Jiajia;  Shi, Dayong
Adobe PDF(579Kb)  |  收藏  |  浏览/下载:267/0  |  提交时间:2020/09/23
Novel compound  Quantitation  UHPLC-TOF-MS  Pharmacokinetics  
Draft genomes of two Atlantic bay scallop subspecies Argopecten irradians irradians and A. i. concentricus 期刊论文
SCIENTIFIC DATA, 2020, 卷号: 7, 期号: 1, 页码: 8
作者:  Liu, Xiao;  Li, Chao;  Chen, Min;  Liu, Bo;  Yan, Xiaojun;  Ning, Junhao;  Ma, Bin;  Liu, Guilong;  Zhong, Zhaoshan;  Jia, Yanglei;  Shi, Qiong;  Wang, Chunde
Adobe PDF(2043Kb)  |  收藏  |  浏览/下载:267/0  |  提交时间:2020/09/23
Structural and Bioactive Studies of Halogenated Constituents from Sponges 期刊论文
CURRENT MEDICINAL CHEMISTRY, 2020, 卷号: 27, 期号: 14, 页码: 2335-2360
作者:  Li, Chao;  Shi, Dayong
收藏  |  浏览/下载:309/0  |  提交时间:2020/09/24
Halogenated  sponges  marine  isolate  constitutes  activity  
Inhibition of PTP1B blocks pancreatic cancer progression by targeting the PKM2/AMPK/mTOC1 pathway 期刊论文
CELL DEATH & DISEASE, 2019, 卷号: 10, 页码: 15
作者:  Xu, Qi;  Wu, Ning;  Li, Xiangqian;  Guo, Chuanlong;  Li, Chao;  Jiang, Bo;  Wang, Huaizhi;  Shi, Dayong
Adobe PDF(3632Kb)  |  收藏  |  浏览/下载:417/0  |  提交时间:2020/03/20
Design, synthesis and biological evaluation of bromophenol-thiazolylhydrazone hybrids inhibiting the interaction of translation initiation factors eIF4E/eIF4G as multifunctional agents for cancer treatment 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 177, 页码: 153-170
作者:  Wang, Lijun;  Guo, Chuanlong;  Li, Xiuxue;  Yu, Xuemin;  Li, Xiangqian;  Xu, Kuo;  Jiang, Bo;  Jia, Xiaoling;  Li, Chao;  Shi, Dayong
Adobe PDF(4835Kb)  |  收藏  |  浏览/下载:451/0  |  提交时间:2019/08/29
Bromophenol-thiazolylhydrazone hybrids  Synthesis  Multifunctional agents  eIF4E/eIF4G interaction  Autophagy  ROS  
海洋天然产物BDDPM靶向调控PTP1B的降糖作用及机制研究 学位论文
, 中国科学院海洋研究所: 中国科学院大学, 2019
作者:  李超
Adobe PDF(6659Kb)  |  收藏  |  浏览/下载:239/0  |  提交时间:2019/06/17
Highly Selective Protein Tyrosine Phosphatase Inhibitor, 2,2 ',3,3 '-Tetrabromo-4,4 ',5,5 '-tetrahydroxydiphenylmethane, Ameliorates Type 2 Diabetes Mellitus in BKS db Mice 期刊论文
MOLECULAR PHARMACEUTICS, 2019, 卷号: 16, 期号: 5, 页码: 1839-1850
作者:  Li, Chao;  Luo, Jiao;  Guo, Shuju;  Jia, Xiaoling;  Guo, Chuanlong;  Li, Xiangqian;  Xu, Qi;  Shi, Dayong
收藏  |  浏览/下载:445/0  |  提交时间:2019/08/28
type 2 diabetes mellitus  protein tyrosine phosphatase 1B  insulin resistance  hypoglycemic activity  dyslipidemia