| Beta-chitosan extracted from Loligo Japonica for a potential use to inhibit Newcastle disease | |
He, Xiaofei1,2; Xing, Ronge1 ; Li, Kecheng1; Qin, Yukun1; Zou, Ping1,2; Liu, Song1; Yu, Huahua1; Li, Pengcheng1
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| 2016 | |
| 发表期刊 | INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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| 卷号 | 82期号:2016页码:614-620 |
| 文章类型 | Article |
| 摘要 | Beta-chitosan has a parallel structure, which differs from alpha-chitosan's antiparallel structure while producing different properties and difficulties. In this paper, we prepared the beta-chitosan through acid and alkali methods and the resultant material was characterized by elemental analysis, FT-IR, HPLC, XRD, NMR and AFS. To increase the solubility and biological activity of the beta-chitosan, we degraded it through microwave-assisted process. After characterization, we determined that the chitosan had not changed its configuration during the reaction with H2O2 under microwave irradiation. The inhibitory activity of the degraded chitosan for Newcastle disease was revealed by a hemagglutination test and RT-PCR. The yield of the beta-chitosan was approximately 30%, and its molecular weight can be degraded to 1000 to 10,000 g/mol. Moreover, the degraded p-chitosan has higher antiviral activity, reducing the hemagglutination titre to zero, compared with alpha-chitosan. Therefore, beta-chitosan has good development prospects during the development of veterinary drugs for Newcastle disease. (c) 2015 Elsevier B.V. All rights reserved. |
| 关键词 | Degraded Beta-chitosan Microwave-assisted Antiviral Activities For Newcastle Disease |
| DOI | 10.1016/j.ijbiomac.2015.10.059 |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000367425100077 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.qdio.ac.cn/handle/337002/86656 |
| 专题 | 海洋生物技术研发中心 海洋环境工程技术研究发展中心 |
| 作者单位 | 1.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
| 第一作者单位 | 实验海洋生物学重点实验室 |
| 推荐引用方式 GB/T 7714 | He, Xiaofei,Xing, Ronge,Li, Kecheng,et al. Beta-chitosan extracted from Loligo Japonica for a potential use to inhibit Newcastle disease[J]. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,2016,82(2016):614-620. |
| APA | He, Xiaofei.,Xing, Ronge.,Li, Kecheng.,Qin, Yukun.,Zou, Ping.,...&Li, Pengcheng.(2016).Beta-chitosan extracted from Loligo Japonica for a potential use to inhibit Newcastle disease.INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,82(2016),614-620. |
| MLA | He, Xiaofei,et al."Beta-chitosan extracted from Loligo Japonica for a potential use to inhibit Newcastle disease".INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES 82.2016(2016):614-620. |
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| 文件名称/大小 | 文献类型 | 版本类型 | 开放类型 | 使用许可 | ||
| Beta-chitosan extrac（1119KB） | 期刊论文 | 出版稿 | 限制开放 | CC BY-NC-SA | 浏览 | |
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