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Highly Oxygenated Triterpenoids from the Marine Red Alga Laurencia mariannensis (Rhodomelaceae)
Ji, Nai-Yun1,2; Li, Xiao-Ming1; Xie, Hua3; Ding, Jian3; Li, Ke1,2; Ding, Lan-Ping1; Wang, Bin-Gui1
2008
发表期刊HELVETICA CHIMICA ACTA
ISSN0018-019X
卷号91期号:10页码:1940-1946
文章类型Article
摘要Two new and one known squalenoid-derived triterpenoids. namely, laurenmariannol (1) and (21 alpha)-21-hydroxythyrsiferol (2). and the known thyrsiferol (3) were isolated and identified from the marine red alga Laurencia mariannensis, which was collected off the coast of Hainan and Weizhou Islands of China. The structures of these compounds were established by means of spectroscopic analyses, as well as by comparison with literature data. Compounds I and 2 displayed significant cytotoxic activity against P-388 tumor cells with IC(50) values of 0.6 and 6.6 mu g/ml, respectively.; Two new and one known squalenoid-derived triterpenoids. namely, laurenmariannol (1) and (21 alpha)-21-hydroxythyrsiferol (2). and the known thyrsiferol (3) were isolated and identified from the marine red alga Laurencia mariannensis, which was collected off the coast of Hainan and Weizhou Islands of China. The structures of these compounds were established by means of spectroscopic analyses, as well as by comparison with literature data. Compounds I and 2 displayed significant cytotoxic activity against P-388 tumor cells with IC50 values of 0.6 and 6.6 mu g/ml, respectively.
关键词Radical-scavenging Activity Polysiphonia-urceolata Thyrsiferyl 23-acetate Sesquiterpenes Bromophenols Apoptosis Decumbens
收录类别SCI ; IC
语种英语
WOS记录号WOS:000261050300014
引用统计
被引频次:30[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.qdio.ac.cn/handle/337002/6282
专题实验海洋生物学重点实验室
作者单位1.Chinese Acad Sci, Inst Oceanol, Qingdao 266071, Peoples R China
2.Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China
3.Chinese Acad Sci, Shanghai Inst Biol Sci, State Key Lab Drug Res, Inst Mat Med, Shanghai 201203, Peoples R China
第一作者单位中国科学院海洋研究所
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Ji, Nai-Yun,Li, Xiao-Ming,Xie, Hua,et al. Highly Oxygenated Triterpenoids from the Marine Red Alga Laurencia mariannensis (Rhodomelaceae)[J]. HELVETICA CHIMICA ACTA,2008,91(10):1940-1946.
APA Ji, Nai-Yun.,Li, Xiao-Ming.,Xie, Hua.,Ding, Jian.,Li, Ke.,...&Wang, Bin-Gui.(2008).Highly Oxygenated Triterpenoids from the Marine Red Alga Laurencia mariannensis (Rhodomelaceae).HELVETICA CHIMICA ACTA,91(10),1940-1946.
MLA Ji, Nai-Yun,et al."Highly Oxygenated Triterpenoids from the Marine Red Alga Laurencia mariannensis (Rhodomelaceae)".HELVETICA CHIMICA ACTA 91.10(2008):1940-1946.
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