Institutional Repository of Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences
Highly Oxygenated Triterpenoids from the Marine Red Alga Laurencia mariannensis (Rhodomelaceae) | |
Ji, Nai-Yun1,2; Li, Xiao-Ming1; Xie, Hua3; Ding, Jian3; Li, Ke1,2; Ding, Lan-Ping1; Wang, Bin-Gui1 | |
2008 | |
发表期刊 | HELVETICA CHIMICA ACTA |
ISSN | 0018-019X |
卷号 | 91期号:10页码:1940-1946 |
文章类型 | Article |
摘要 | Two new and one known squalenoid-derived triterpenoids. namely, laurenmariannol (1) and (21 alpha)-21-hydroxythyrsiferol (2). and the known thyrsiferol (3) were isolated and identified from the marine red alga Laurencia mariannensis, which was collected off the coast of Hainan and Weizhou Islands of China. The structures of these compounds were established by means of spectroscopic analyses, as well as by comparison with literature data. Compounds I and 2 displayed significant cytotoxic activity against P-388 tumor cells with IC(50) values of 0.6 and 6.6 mu g/ml, respectively.; Two new and one known squalenoid-derived triterpenoids. namely, laurenmariannol (1) and (21 alpha)-21-hydroxythyrsiferol (2). and the known thyrsiferol (3) were isolated and identified from the marine red alga Laurencia mariannensis, which was collected off the coast of Hainan and Weizhou Islands of China. The structures of these compounds were established by means of spectroscopic analyses, as well as by comparison with literature data. Compounds I and 2 displayed significant cytotoxic activity against P-388 tumor cells with IC50 values of 0.6 and 6.6 mu g/ml, respectively. |
关键词 | Radical-scavenging Activity Polysiphonia-urceolata Thyrsiferyl 23-acetate Sesquiterpenes Bromophenols Apoptosis Decumbens |
收录类别 | SCI ; IC |
语种 | 英语 |
WOS记录号 | WOS:000261050300014 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.qdio.ac.cn/handle/337002/6282 |
专题 | 实验海洋生物学重点实验室 |
作者单位 | 1.Chinese Acad Sci, Inst Oceanol, Qingdao 266071, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China 3.Chinese Acad Sci, Shanghai Inst Biol Sci, State Key Lab Drug Res, Inst Mat Med, Shanghai 201203, Peoples R China |
第一作者单位 | 中国科学院海洋研究所 |
推荐引用方式 GB/T 7714 | Ji, Nai-Yun,Li, Xiao-Ming,Xie, Hua,et al. Highly Oxygenated Triterpenoids from the Marine Red Alga Laurencia mariannensis (Rhodomelaceae)[J]. HELVETICA CHIMICA ACTA,2008,91(10):1940-1946. |
APA | Ji, Nai-Yun.,Li, Xiao-Ming.,Xie, Hua.,Ding, Jian.,Li, Ke.,...&Wang, Bin-Gui.(2008).Highly Oxygenated Triterpenoids from the Marine Red Alga Laurencia mariannensis (Rhodomelaceae).HELVETICA CHIMICA ACTA,91(10),1940-1946. |
MLA | Ji, Nai-Yun,et al."Highly Oxygenated Triterpenoids from the Marine Red Alga Laurencia mariannensis (Rhodomelaceae)".HELVETICA CHIMICA ACTA 91.10(2008):1940-1946. |
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