| Relevance of molecular weight of chitosan-N-2-hydroxypropyl trimethyl ammonium chloride and their antioxidant activities | |
Xing, Ronge1 ; Liu, Song1; Guo, Zhanyong1,2; Yu, Huahua1; Zhong, Zhimei1,2; Ji, Xia1,2; Li, Pengcheng1
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| 2008-02-01 | |
| 发表期刊 | EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
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| ISSN | 0223-5234 |
| 卷号 | 43期号:2页码:336-340 |
| 文章类型 | Article |
| 摘要 | The antioxidant potency of high/low molecular weight quatemary chitosan derivatives was investigated employing various established systems in vitro, such as superoxide (O(2)(center dot-)) and hydroxyl (center dot OH) radicals scavenging, reducing power and iron ion chelating. As expected, we obtained several satisfying results, as follow: firstly, low molecular weight quaternary chitosan had stronger scavenging effect on O(2)(center dot-) and center dot OH than high molecular weight quaternary chitosan. Secondly, the reducing power of low molecular weight quaternary chitosan was more pronounced than that of high molecular weight quaternary chitosan. Thirdly, ferrous ion chelating potency were showed to increase first and decrease afterwards with increasing concentration for two kinds of quaternary chitosans, namely, they have not concentration-dependence. However, the scavenging rate and reducing power of high and low molecular weight quaternary chitosans increased with their increasing conc centrations, and hence were concentration-dependent. (c) 2007 Elsevier Masson SAS. All rights reserved.; The antioxidant potency of high/low molecular weight quatemary chitosan derivatives was investigated employing various established systems in vitro, such as superoxide (O-2(center dot-)) and hydroxyl (center dot OH) radicals scavenging, reducing power and iron ion chelating. As expected, we obtained several satisfying results, as follow: firstly, low molecular weight quaternary chitosan had stronger scavenging effect on O-2(center dot-) and center dot OH than high molecular weight quaternary chitosan. Secondly, the reducing power of low molecular weight quaternary chitosan was more pronounced than that of high molecular weight quaternary chitosan. Thirdly, ferrous ion chelating potency were showed to increase first and decrease afterwards with increasing concentration for two kinds of quaternary chitosans, namely, they have not concentration-dependence. However, the scavenging rate and reducing power of high and low molecular weight quaternary chitosans increased with their increasing conc centrations, and hence were concentration-dependent. (c) 2007 Elsevier Masson SAS. All rights reserved. |
| 关键词 | High Molecular Weight Chitosan-n-2-hydroxypropyl Trimethyl Ammonium Chloride Low Molecular Weight Chitosan-n-2-hydroxypropyl Trimethyl Ammonium Chloride Radical Scavenging Effect Reducing Power Chelating Effect Comparative Relevance |
| 学科领域 | Chemistry, Medicinal |
| DOI | 10.1016/j.ejmech.2007.03.025 |
| URL | 查看原文 |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000254031400012 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.qdio.ac.cn/handle/337002/6106 |
| 专题 | 海洋生物技术研发中心 海洋环境工程技术研究发展中心 |
| 作者单位 | 1.Chinese Acad Sci, Inst Oceanol, Qingdao 266071, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China |
| 第一作者单位 | 中国科学院海洋研究所 |
| 推荐引用方式 GB/T 7714 | Xing, Ronge,Liu, Song,Guo, Zhanyong,et al. Relevance of molecular weight of chitosan-N-2-hydroxypropyl trimethyl ammonium chloride and their antioxidant activities[J]. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY,2008,43(2):336-340. |
| APA | Xing, Ronge.,Liu, Song.,Guo, Zhanyong.,Yu, Huahua.,Zhong, Zhimei.,...&Li, Pengcheng.(2008).Relevance of molecular weight of chitosan-N-2-hydroxypropyl trimethyl ammonium chloride and their antioxidant activities.EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY,43(2),336-340. |
| MLA | Xing, Ronge,et al."Relevance of molecular weight of chitosan-N-2-hydroxypropyl trimethyl ammonium chloride and their antioxidant activities".EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 43.2(2008):336-340. |
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