| Steroids from green alga Chaetomorpha basiretorsa Setchell | |
| Shi Dayong1; Fan Xiao1; Sun Jie1; Han Lijun1; Shi Jiangong2,3 | |
| 2008-11-01 | |
| 发表期刊 | CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY
 |
| ISSN | 0254-4059 |
| 卷号 | 26期号:4页码:415-418 |
| 文章类型 | Article |
| 摘要 | Six steroids have been isolated from ethanolic extract of green alga Chaetomorpha basiretorsa Setchell by a combination of repeated normal phase silica gel and Sephadex LH-20 gel column chromatography as well as recrystallization. Using spectroscopic methods including MS and NMR, their structures were determined as beta-lawsaritol (1), saringosterol (2), 24-hydroperoxy-24-vinyl-cholesterol (3), beta-stigmasterol (4), stigmast-4-en-3 alpha, 6 beta-diol (5), 29-hydroxystigmasta-5, 24 (28)-dien-3 beta-ol (6). All these compounds were obtained from this genus for the first time and they were inactive (IC(50)> 10 mu g /ml) against KB, Bel-7402, PC-3M, Ketr 3 and MCF-7 cell lines.; Six steroids have been isolated from ethanolic extract of green alga Chaetomorpha basiretorsa Setchell by a combination of repeated normal phase silica gel and Sephadex LH-20 gel column chromatography as well as recrystallization. Using spectroscopic methods including MS and NMR, their structures were determined as beta-lawsaritol (1), saringosterol (2), 24-hydroperoxy-24-vinyl-cholesterol (3), beta-stigmasterol (4), stigmast-4-en-3 alpha, 6 beta-diol (5), 29-hydroxystigmasta-5, 24 (28)-dien-3 beta-ol (6). All these compounds were obtained from this genus for the first time and they were inactive (IC50 > 10 mu g /ml) against KB, Bel-7402, PC-3M, Ketr 3 and MCF-7 cell lines. |
| 关键词 | Green Alga Chaetomorpha Basiretorsa Setchell Steroids |
| 学科领域 | Limnology ; Oceanography |
| DOI | 10.1007/s00343-008-0415-7 |
| URL | 查看原文 |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000262669100013 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.qdio.ac.cn/handle/337002/6088 |
| 专题 | 海洋生物技术研发中心 |
| 作者单位 | 1.Chinese Acad Sci, Inst Oceanol, Qingdao 266071, Peoples R China 2.Chinese Acad Med Sci, Inst Mat Med, Beijing 10005, Peoples R China 3.Peking Union Med Coll, Beijing 10005, Peoples R China |
| 第一作者单位 | 中国科学院海洋研究所 |
| 推荐引用方式 GB/T 7714 | Shi Dayong,Fan Xiao,Sun Jie,et al. Steroids from green alga Chaetomorpha basiretorsa Setchell[J]. CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY,2008,26(4):415-418. |
| APA | Shi Dayong,Fan Xiao,Sun Jie,Han Lijun,&Shi Jiangong.(2008).Steroids from green alga Chaetomorpha basiretorsa Setchell.CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY,26(4),415-418. |
| MLA | Shi Dayong,et al."Steroids from green alga Chaetomorpha basiretorsa Setchell".CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY 26.4(2008):415-418. |
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