New sphingolipids with a previously unreported 9-Methyl-C-20-sphingosine moiety from a marine algous endophytic fungus Aspergillus niger EN-13

doi:10.1007/s11745-007-3079-8

IOCAS-IR > 实验海洋生物学重点实验室

	New sphingolipids with a previously unreported 9-Methyl-C-20-sphingosine moiety from a marine algous endophytic fungus Aspergillus niger EN-13
	Zhang, Yi ; Wang, Song ; Li, Xiao-Ming ; Cui, Chuan-Ming ; Feng, Chao ; Wang, Bin-Gui
	2007-08-01
发表期刊	LIPIDS
ISSN	0024-4201
卷号	42 期号:8 页码:759-764
文章类型	Article
摘要	Asperamides A (1) and B (2), a sphingolipid and their corresponding glycosphingolipid possessing a hitherto unreported 9-methyl-C-20-sphingosine moiety, were characterized from the culture extract of Aspergillus niger EN-13, an endophytic fungus isolated from marine brown alga Colpomenia sinuosa. The structures were elucidated by spectroscopic and chemical methods as (2S,2'R,3R,3'E,4E,8E)-N-(2'-hydroxy-3'-hexadecenoyl)-9-methyl-4,8-icosadien-1,3-diol (1) and 1-O-beta-D-glucopyranosyl-(2S,2'R,3R,3'E,4E,8E)-N-(2'-hydroxy-3'-hexadecenoyl)-9-methyl-4,8-icosadien-1,3-diol (2). In the antifungal assay, asperamide A (1) displayed moderate activity against Candida albicans.; Asperamides A (1) and B (2), a sphingolipid and their corresponding glycosphingolipid possessing a hitherto unreported 9-methyl-C-20-sphingosine moiety, were characterized from the culture extract of Aspergillus niger EN-13, an endophytic fungus isolated from marine brown alga Colpomenia sinuosa. The structures were elucidated by spectroscopic and chemical methods as (2S,2'R,3R,3'E,4E,8E)-N-(2'-hydroxy-3'-hexadecenoyl)-9-methyl-4,8-icosadien-1,3-diol (1) and 1-O-beta-D-glucopyranosyl-(2S,2'R,3R,3'E,4E,8E)-N-(2'-hydroxy-3'-hexadecenoyl)-9-methyl-4,8-icosadien-1,3-diol (2). In the antifungal assay, asperamide A (1) displayed moderate activity against Candida albicans.
关键词	Marine Alga Colpomenia Sinuosa Nndophytic Fungus Aspergillus Niger Sphingolipid Glycosphingolipid Asperamide a Asperamide b
学科领域	Biochemistry & Molecular Biology ; Nutrition & Dietetics
DOI	10.1007/s11745-007-3079-8
URL	查看原文
收录类别	SCI
语种	英语
WOS记录号	WOS:000248303800009
引用统计	被引频次：60[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.qdio.ac.cn/handle/337002/5742
专题	实验海洋生物学重点实验室
作者单位	1.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China
推荐引用方式 GB/T 7714	Zhang, Yi,Wang, Song,Li, Xiao-Ming,et al. New sphingolipids with a previously unreported 9-Methyl-C-20-sphingosine moiety from a marine algous endophytic fungus Aspergillus niger EN-13[J]. LIPIDS,2007,42(8):759-764.
APA	Zhang, Yi,Wang, Song,Li, Xiao-Ming,Cui, Chuan-Ming,Feng, Chao,&Wang, Bin-Gui.(2007).New sphingolipids with a previously unreported 9-Methyl-C-20-sphingosine moiety from a marine algous endophytic fungus Aspergillus niger EN-13.LIPIDS,42(8),759-764.
MLA	Zhang, Yi,et al."New sphingolipids with a previously unreported 9-Methyl-C-20-sphingosine moiety from a marine algous endophytic fungus Aspergillus niger EN-13".LIPIDS 42.8(2007):759-764.

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