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Reviews on The Immunological Function of Tetraspanins | |
Gui Lang; Wang Bing; Li Fu-Hua; Xiang Jian-Hai | |
2008-11-01 | |
发表期刊 | PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS |
ISSN | 1000-3282 |
卷号 | 35期号:11页码:1231-1238 |
文章类型 | Review |
摘要 | Tetraspanins belongs to the transmembrane 4 superfamily(TM4SF). They can be as a bridge to connect the proteins outside or inside the cell membrane. A tetraspanins web is formed by the tetraspnins-proteins complex, and the web is believed to involve in fundamental functions of immunity system, and consequnently, signaling between cells and inside cells, regulating cell activation and adhesion, participating in the identification and infection of some virus. As a family of conservative transmembrane proteins, tetraspanins play multiplex roles in invertebrate. It was described how tetraspanin microdomains might have functions in the immune system, and how they contact with virus. In addition, the important role of tetraspanins in the innate immune system of invertebrate were discussed.; Tetraspanins belongs to the transmembrane 4 superfamily(TM4SF). They can be as a bridge to connect the proteins outside or inside the cell membrane. A tetraspanins web is formed by the tetraspnins-proteins complex, and the web is believed to involve in fundamental functions of immunity system, and consequnently, signaling between cells and inside cells, regulating cell activation and adhesion, participating in the identification and infection of some virus. As a family of conservative transmembrane proteins, tetraspanins play multiplex roles in invertebrate. It was described how tetraspanin microdomains might have functions in the immune system, and how they contact with virus. In addition, the important role of tetraspanins in the innate immune system of invertebrate were discussed. |
关键词 | Tetraspanins Immunity Virus Transmembrane 4 Superfamily Invertebrate |
学科领域 | Biochemistry & Molecular Biology ; Biophysics |
收录类别 | SCI |
语种 | 英语 |
WOS记录号 | WOS:000261290200003 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.qdio.ac.cn/handle/337002/5564 |
专题 | 实验海洋生物学重点实验室 |
作者单位 | Chinese Acad Sci, Inst Oceanol, Qingdao 266071, Peoples R China |
第一作者单位 | 中国科学院海洋研究所 |
推荐引用方式 GB/T 7714 | Gui Lang,Wang Bing,Li Fu-Hua,et al. Reviews on The Immunological Function of Tetraspanins[J]. PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS,2008,35(11):1231-1238. |
APA | Gui Lang,Wang Bing,Li Fu-Hua,&Xiang Jian-Hai.(2008).Reviews on The Immunological Function of Tetraspanins.PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS,35(11),1231-1238. |
MLA | Gui Lang,et al."Reviews on The Immunological Function of Tetraspanins".PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS 35.11(2008):1231-1238. |
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