| The structure of a sulfated galactan from Porphyra haitanensis and its in vivo antioxidant activity |
| Zhang, QB; Li, N; Liu, XG; Zhao, ZQ; Li, Z ; Xu, ZH
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| 2004-01-02
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| 发表期刊 | CARBOHYDRATE RESEARCH
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| ISSN | 0008-6215
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| 卷号 | 339期号:1页码:105-+ |
| 文章类型 | Article
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| 摘要 | The sulfated galactan fraction F1 isolated from the red seaweed, Porphyra haitanensis, showed typical porphyran structure. It has a linear backbone of alternating 3-linked beta-D-galactosyl units and 4-linked alpha-L-galactosyl 6-sulfate and 3,6-anhydro-alpha-L-galactosyl units. The L-residues are mainly composed of alpha-L-galactosyl 6-sulfate units, and the 3,6-anhydrogalactosyl units are minor. Partial methylation occurred at the C-6 position of the D-galactosyl units and at the C-2 position of the 3,6-anhydro-alpha-L-galactosyl units. Intraperitoneal administration of F1 significantly decreased the lipid peroxidation in aging mice. F1 treatment increased the total antioxidant capacity and the activity of superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) in aging mice. The results indicated that F1 had significant in vivo antioxidant activity. (C) 2003 Elsevier Ltd. All rights reserved.; The sulfated galactan fraction F1 isolated from the red seaweed, Porphyra haitanensis, showed typical porphyran structure. It has a linear backbone of alternating 3-linked beta-D-galactosyl units and 4-linked alpha-L-galactosyl 6-sulfate and 3,6-anhydro-alpha-L-galactosyl units. The L-residues are mainly composed of alpha-L-galactosyl 6-sulfate units, and the 3,6-anhydrogalactosyl units are minor. Partial methylation occurred at the C-6 position of the D-galactosyl units and at the C-2 position of the 3,6-anhydro-alpha-L-galactosyl units. Intraperitoneal administration of F1 significantly decreased the lipid peroxidation in aging mice. F1 treatment increased the total antioxidant capacity and the activity of superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) in aging mice. The results indicated that F1 had significant in vivo antioxidant activity. (C) 2003 Elsevier Ltd. All rights reserved. |
| 关键词 | Porphyra Haitanensis
Sulfated Galactan
Chemical Structure
Nmr Spectroscopy
In Vivo Antioxidant Activity
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| 学科领域 | Biochemistry & Molecular Biology
; Chemistry, Applied
; Chemistry, Organic
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| DOI | 10.1016/j.carres.2003.09.015
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| URL | 查看原文
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| 收录类别 | SCI
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| 语种 | 英语
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| WOS记录号 | WOS:000187803900011
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| 引用统计 |
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| 文献类型 | 期刊论文
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| 条目标识符 | http://ir.qdio.ac.cn/handle/337002/3580
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| 专题 | 海洋生物技术研发中心
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| 作者单位 | Chinese Acad Sci, Inst Oceanol, Qingdao 266071, Peoples R China
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推荐引用方式
GB/T 7714 |
Zhang, QB,Li, N,Liu, XG,et al. The structure of a sulfated galactan from Porphyra haitanensis and its in vivo antioxidant activity[J]. CARBOHYDRATE RESEARCH,2004,339(1):105-+.
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| APA |
Zhang, QB,Li, N,Liu, XG,Zhao, ZQ,Li, Z,&Xu, ZH.(2004).The structure of a sulfated galactan from Porphyra haitanensis and its in vivo antioxidant activity.CARBOHYDRATE RESEARCH,339(1),105-+.
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| MLA |
Zhang, QB,et al."The structure of a sulfated galactan from Porphyra haitanensis and its in vivo antioxidant activity".CARBOHYDRATE RESEARCH 339.1(2004):105-+.
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