| Effects of fucoidan on chronic renal failure in rats | |
Zhang, QB; Li, Z ; Xu, ZH; Niu, XZ; Zhang, H
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| 2003-06-01 | |
| 发表期刊 | PLANTA MEDICA
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| 卷号 | 69期号:6页码:537-541 |
| 文章类型 | Article |
| 摘要 | The effects of fucoidan on chronic renal failure (CRF) were investigated in vivo in a subtotal nephrectomy CRF model and a cryoinjury induced CRF model in rats. Fucoidan showed renoprotective effects in both models. Fucoidan (100 or 200 mg/kg, orally) significantly decreased elevated serum creatinine and urea nitrogen levels. Histopathological changes of renal. tubules and interstitium were markedly alleviated by fucoidan and the mesangial areas were also greatly reduced. The activities of fucoidan were dose-dependent. |
| 关键词 | Laminaria Japonica Laminariaceae Fucoidan Chronic Renal Failure Serum Creatinine Serum Urea Nitrogen |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000184144600011 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.qdio.ac.cn/handle/337002/33004 |
| 专题 | 海洋生物技术研发中心 |
| 作者单位 | 1.Acad Sinica, Inst Oceanol, Qingdao 266071, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhang, QB,Li, Z,Xu, ZH,et al. Effects of fucoidan on chronic renal failure in rats[J]. PLANTA MEDICA,2003,69(6):537-541. |
| APA | Zhang, QB,Li, Z,Xu, ZH,Niu, XZ,&Zhang, H.(2003).Effects of fucoidan on chronic renal failure in rats.PLANTA MEDICA,69(6),537-541. |
| MLA | Zhang, QB,et al."Effects of fucoidan on chronic renal failure in rats".PLANTA MEDICA 69.6(2003):537-541. |
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