A review of advances in research on marine molluscan antimicrobial peptides and their potential application in aquaculture

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	A review of advances in research on marine molluscan antimicrobial peptides and their potential application in aquaculture
	Li Cheng-Hua 1; Zhao Jian-Min 2; Song Lin-Sheng 2
	2009
发表期刊	MOLLUSCAN RESEARCH
ISSN	1323-5818
卷号	29 期号:1 页码:17-26
文章类型	Review
摘要	Antimicrobial peptides (AMPs) are important components of the host innate immune response against microbial invasion. They are usually characterized by their small-size, heat-stability and broad range of antimicrobial activity. This review covers research advances on marine mollusc AMPs, specifically those isolated from mussels, scallops, oysters, venerid clams and abalone, which mainly include MGD, mytilin, myticin, mytimycin, big defensin, and RPD-1. Their structural characteristics, antibacterial activity, and expression pattern as well as peptide distribution and their release following microbial challenge are also discussed. In addition, the prospect of the application of AMPs as food additives or their use in immunostimulation to prevent diseases of aquatic animals, as well as their potential hazards, are also discussed.; Antimicrobial peptides (AMPs) are important components of the host innate immune response against microbial invasion. They are usually characterized by their small-size, heat-stability and broad range of antimicrobial activity. This review covers research advances on marine mollusc AMPs, specifically those isolated from mussels, scallops, oysters, venerid clams and abalone, which mainly include MGD, mytilin, myticin, mytimycin, big defensin, and RPD-1. Their structural characteristics, antibacterial activity, and expression pattern as well as peptide distribution and their release following microbial challenge are also discussed. In addition, the prospect of the application of AMPs as food additives or their use in immunostimulation to prevent diseases of aquatic animals, as well as their potential hazards, are also discussed.
关键词	Innate Immunity Immunostimulation Oysters Scallops Mussels Abalone
学科领域	Marine & Freshwater Biology ; Zoology
收录类别	SCI
语种	英语
WOS记录号	WOS:000267011500002
引用统计	被引频次：48[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.qdio.ac.cn/handle/337002/2934
专题	实验海洋生物学重点实验室
作者单位	1.Chinese Acad Sci, Yantai Inst Coastal Zone Res Sustainable Dev, Yantai 264003, Peoples R China 2.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China
推荐引用方式 GB/T 7714	Li Cheng-Hua,Zhao Jian-Min,Song Lin-Sheng. A review of advances in research on marine molluscan antimicrobial peptides and their potential application in aquaculture[J]. MOLLUSCAN RESEARCH,2009,29(1):17-26.
APA	Li Cheng-Hua,Zhao Jian-Min,&Song Lin-Sheng.(2009).A review of advances in research on marine molluscan antimicrobial peptides and their potential application in aquaculture.MOLLUSCAN RESEARCH,29(1),17-26.
MLA	Li Cheng-Hua,et al."A review of advances in research on marine molluscan antimicrobial peptides and their potential application in aquaculture".MOLLUSCAN RESEARCH 29.1(2009):17-26.

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