Institutional Repository of Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences
Penicibrocazines A-E, Five New Sulfide Diketopiperazines from the Marine-Derived Endophytic Fungus Penicillium brocae | |
Meng, Ling-Hong1,2; Zhang, Peng1,2; Li, Xiao-Ming1; Wang, Bin-Gui1 | |
2015 | |
发表期刊 | MARINE DRUGS |
卷号 | 13期号:1页码:276-287 |
文章类型 | Article |
摘要 | Five new sulfide diketopiperazine derivatives, namely, penicibrocazines A-E (1-5), along with a known congener (6), were isolated and identified from the culture extract of Penicillium brocae MA-231, an endophytic fungus obtained from the fresh tissue of the marine mangrove plant Avicennia marina. The structures of these compounds were elucidated by detailed interpretation of NMR and mass spectroscopic data and the structures of compounds 1 and 3 were confirmed by single-crystal X-ray diffraction analysis. All these compounds were examined for cytotoxic and antimicrobial activities. Compounds 2-6 exhibited antimicrobial activity against some of the tested strains with MIC values ranging from 0.25 to 64 mu g/mL. |
关键词 | Mangrove Plant Endophytic Fungus Pencillium Brocae Secondary Metabolites Antimicrobial Activity |
DOI | 10.3390/md13010276 |
收录类别 | SCI |
语种 | 英语 |
WOS记录号 | WOS:000348403200016 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.qdio.ac.cn/handle/337002/25351 |
专题 | 实验海洋生物学重点实验室 |
作者单位 | 1.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China 2.Univ Chinese Acad Sci, Coll Earth Sci, Beijing 100049, Peoples R China |
第一作者单位 | 实验海洋生物学重点实验室 |
推荐引用方式 GB/T 7714 | Meng, Ling-Hong,Zhang, Peng,Li, Xiao-Ming,et al. Penicibrocazines A-E, Five New Sulfide Diketopiperazines from the Marine-Derived Endophytic Fungus Penicillium brocae[J]. MARINE DRUGS,2015,13(1):276-287. |
APA | Meng, Ling-Hong,Zhang, Peng,Li, Xiao-Ming,&Wang, Bin-Gui.(2015).Penicibrocazines A-E, Five New Sulfide Diketopiperazines from the Marine-Derived Endophytic Fungus Penicillium brocae.MARINE DRUGS,13(1),276-287. |
MLA | Meng, Ling-Hong,et al."Penicibrocazines A-E, Five New Sulfide Diketopiperazines from the Marine-Derived Endophytic Fungus Penicillium brocae".MARINE DRUGS 13.1(2015):276-287. |
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文件名称/大小 | 文献类型 | 版本类型 | 开放类型 | 使用许可 | ||
Penicibrocazines A-E(771KB) | 期刊论文 | 出版稿 | 限制开放 | ODC PDDL | 浏览 |
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