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Penicibrocazines A-E, Five New Sulfide Diketopiperazines from the Marine-Derived Endophytic Fungus Penicillium brocae
Meng, Ling-Hong1,2; Zhang, Peng1,2; Li, Xiao-Ming1; Wang, Bin-Gui1
2015
发表期刊MARINE DRUGS
卷号13期号:1页码:276-287
文章类型Article
摘要Five new sulfide diketopiperazine derivatives, namely, penicibrocazines A-E (1-5), along with a known congener (6), were isolated and identified from the culture extract of Penicillium brocae MA-231, an endophytic fungus obtained from the fresh tissue of the marine mangrove plant Avicennia marina. The structures of these compounds were elucidated by detailed interpretation of NMR and mass spectroscopic data and the structures of compounds 1 and 3 were confirmed by single-crystal X-ray diffraction analysis. All these compounds were examined for cytotoxic and antimicrobial activities. Compounds 2-6 exhibited antimicrobial activity against some of the tested strains with MIC values ranging from 0.25 to 64 mu g/mL.
关键词Mangrove Plant Endophytic Fungus Pencillium Brocae Secondary Metabolites Antimicrobial Activity
DOI10.3390/md13010276
收录类别SCI
语种英语
WOS记录号WOS:000348403200016
引用统计
被引频次:61[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.qdio.ac.cn/handle/337002/25351
专题实验海洋生物学重点实验室
作者单位1.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China
2.Univ Chinese Acad Sci, Coll Earth Sci, Beijing 100049, Peoples R China
第一作者单位实验海洋生物学重点实验室
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GB/T 7714
Meng, Ling-Hong,Zhang, Peng,Li, Xiao-Ming,et al. Penicibrocazines A-E, Five New Sulfide Diketopiperazines from the Marine-Derived Endophytic Fungus Penicillium brocae[J]. MARINE DRUGS,2015,13(1):276-287.
APA Meng, Ling-Hong,Zhang, Peng,Li, Xiao-Ming,&Wang, Bin-Gui.(2015).Penicibrocazines A-E, Five New Sulfide Diketopiperazines from the Marine-Derived Endophytic Fungus Penicillium brocae.MARINE DRUGS,13(1),276-287.
MLA Meng, Ling-Hong,et al."Penicibrocazines A-E, Five New Sulfide Diketopiperazines from the Marine-Derived Endophytic Fungus Penicillium brocae".MARINE DRUGS 13.1(2015):276-287.
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