The modulation of catecholamines on immune response of scallop Chlamys farreri under heat stress

doi:10.1016/j.ygcen.2013.11.006

IOCAS-IR > 实验海洋生物学重点实验室

	The modulation of catecholamines on immune response of scallop Chlamys farreri under heat stress
	Zhang, Huan 1; Zhou, Zhi 1; Yue, Feng 1,2; Wang, Lingling 1; Yang, Chuanyan 1; Wang, Mengqiang1 ; Song, Linsheng 1; Song, LS (reprint author), Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China.
	2014
发表期刊	GENERAL AND COMPARATIVE ENDOCRINOLOGY
卷号	195 页码:116-124
文章类型	Article
摘要	Catecholamines (CAs) play key roles in mediating the physiological responses to various stresses. In the present study, the expression of CA-related genes were examined in the hemocytes of scallop Chlamys farreri under heat stress, and several immune or metabolism-related parameters were investigated after heat stress and adrenoceptor antagonist stimulation. After the scallops were cultured at 28 degrees C, the mRNA expression level of dopa decarboxylase (CfDDC) and alpha-adrenoceptor (Cf alpha AR) increased significantly (P < 0.01), whereas that of monoamine oxidase (CfMAO) was down-regulated in the first 6 h (P < 0.05), and then up-regulated to the maximum level at 24 h (P < 0.01). In the hemocytes of scallops injected with adrenoceptor antagonist, the expression levels of peptidoglycan-recognition protein (CfPGRP-S1) and C-type lectin (CfLec-1) began to increase significantly at 2 and 3 h post propranolol and high temperature treatment, respectively (P < 0.01). While the up-regulation of heat shock protein 70 (CfHSP70) post heat stress was significantly inhibited by prazosin injection (P < 0.01), and that of hexokinase (CfHK) was inhibited by both prazosin and propranolol injection (P < 0.01). Moreover, the remarkable increase of relative specific activity of SOD in the hemolymph post heat stress (P <0.01) was further up-regulated early after prazosin or propranolol injection (P < 0.01), while that of the relative anti-bacterial ability was down-regulated by prazosin or propranolol treatment (P < 0.01). These results collectively indicated that the catecholaminergic neuroendocrine system in scallop could be activated by heat stress to release CAs, which subsequently modulated the immune response and energy metabolism via alpha- and beta-adrenoceptors. (C) 2013 Published by Elsevier Inc.
关键词	Chlamys Farreri Catecholamines Heat Stress Immune Response Immunomodulation Energy Metabolism
学科领域	Endocrinology & Metabolism
DOI	10.1016/j.ygcen.2013.11.006
收录类别	SCI
语种	英语
WOS记录号	WOS:000330257100013
引用统计	被引频次：21[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.qdio.ac.cn/handle/337002/24182
专题	实验海洋生物学重点实验室
通讯作者	Song, LS (reprint author), Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China.
作者单位	1.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China
第一作者单位	实验海洋生物学重点实验室
推荐引用方式 GB/T 7714	Zhang, Huan,Zhou, Zhi,Yue, Feng,et al. The modulation of catecholamines on immune response of scallop Chlamys farreri under heat stress[J]. GENERAL AND COMPARATIVE ENDOCRINOLOGY,2014,195:116-124.
APA	Zhang, Huan.,Zhou, Zhi.,Yue, Feng.,Wang, Lingling.,Yang, Chuanyan.,...&Song, LS .(2014).The modulation of catecholamines on immune response of scallop Chlamys farreri under heat stress.GENERAL AND COMPARATIVE ENDOCRINOLOGY,195,116-124.
MLA	Zhang, Huan,et al."The modulation of catecholamines on immune response of scallop Chlamys farreri under heat stress".GENERAL AND COMPARATIVE ENDOCRINOLOGY 195(2014):116-124.

条目包含的文件
文件名称/大小	文献类型	版本类型	开放类型	使用许可
The modulation of ca（1764KB）			限制开放	ODC PDDL	浏览