Institutional Repository of Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences
| Prenylated Indolediketopiperazine Peroxides and Related Homologues from the Marine Sediment- Derived Fungus Penicillium brefeldianum SD-273 | |
An, Chun-Yan1,2; Li, Xiao-Ming1; Li, Chun-Shun1; Xu, Gang-Ming1; Wang, Bin-Gui1 ; Wang, BG (reprint author), Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Nanhai Rd 7, Qingdao 266071, Peoples R China.
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| 2014-02-01 | |
| 发表期刊 | MARINE DRUGS
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| 卷号 | 12期号:2页码:746-756 |
| 文章类型 | Article |
| 摘要 | Three new indolediketopiperazine peroxides, namely, 24-hydroxyverruculogen (1), 26-hydroxyverruculogen (2), and 13-O-prenyl-26-hydroxyverruculogen (3), along with four known homologues (4-7), were isolated and identified from the culture extract of the marine sediment-derived fungus Penicillium brefeldianum SD-273. Their structures were determined based on the extensive spectroscopic analysis and compound 1 was confirmed by X-ray crystallographic analysis. The absolute configuration of compounds 1-3 was determined using chiral HPLC analysis of their acidic hydrolysates. Each of the isolated compounds was evaluated for antibacterial and cytotoxic activity as well as brine shrimp (Artemia salina) lethality. |
| 关键词 | Marine Sediment Penicillium Brefeldianum Sd-273 Indolediketopiperazine Brine Shrimp Lethality |
| 学科领域 | Pharmacology & Pharmacy |
| DOI | 10.3390/md12020746 |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000335745100008 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.qdio.ac.cn/handle/337002/24150 |
| 专题 | 实验海洋生物学重点实验室 |
| 通讯作者 | Wang, BG (reprint author), Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Nanhai Rd 7, Qingdao 266071, Peoples R China. |
| 作者单位 | 1.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
| 第一作者单位 | 实验海洋生物学重点实验室 |
| 推荐引用方式 GB/T 7714 | An, Chun-Yan,Li, Xiao-Ming,Li, Chun-Shun,et al. Prenylated Indolediketopiperazine Peroxides and Related Homologues from the Marine Sediment- Derived Fungus Penicillium brefeldianum SD-273[J]. MARINE DRUGS,2014,12(2):746-756. |
| APA | An, Chun-Yan,Li, Xiao-Ming,Li, Chun-Shun,Xu, Gang-Ming,Wang, Bin-Gui,&Wang, BG .(2014).Prenylated Indolediketopiperazine Peroxides and Related Homologues from the Marine Sediment- Derived Fungus Penicillium brefeldianum SD-273.MARINE DRUGS,12(2),746-756. |
| MLA | An, Chun-Yan,et al."Prenylated Indolediketopiperazine Peroxides and Related Homologues from the Marine Sediment- Derived Fungus Penicillium brefeldianum SD-273".MARINE DRUGS 12.2(2014):746-756. |
| 条目包含的文件 | ||||||
| 文件名称/大小 | 文献类型 | 版本类型 | 开放类型 | 使用许可 | ||
| Prenylated Indoledik（693KB） | 限制开放 | ODC PDDL | 浏览 | |||
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