A new ALF from Litopenaeus vannamei and its SNPs related to WSSV resistance

doi:10.1007/s00343-015-4010-4

IOCAS-IR > 实验海洋生物学重点实验室

	A new ALF from Litopenaeus vannamei and its SNPs related to WSSV resistance
	Liu Jingwen1,2 ; Yu Yang1,2 ; Li Fuhua 1,3; Zhang Xiaojun 1; Xiang Jianhai1 ; Xiang, JH (reprint author), Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China.
	2014-11-01
发表期刊	CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY
卷号	32 期号:6 页码:1232-1247
文章类型	Article
摘要	Anti-lipopolysaccharide factors (ALFs) are basic components of the crustacean immune system that defend against a range of pathogens. The cDNA sequence of a new ALF, designated nLvALF2, with an open reading frame encoding 132 amino acids was cloned. Its deduced amino acid sequence contained the conserved functional domain of ALFs, the LPS binding domain (LBD). Its genomic sequence consisted of three exons and four introns. nLvALF2 was mainly expressed in the Oka organ and gills of shrimps. The transcriptional level of nLvALF2 increased significantly after white spot syndrome virus (WSSV) infection, suggesting its important roles in protecting shrimps from WSSV. Single nucleotide polymorphisms (SNPs) were found in the genomic sequence of nLvALF2, of which 38 were analyzed for associations with the susceptibility/resistance of shrimps to WSSV. The loci g. 2422 A>G, g. 2466 T>C, and g.2529 G>A were significantly associated with the resistance to WSSV (P<0.05). These SNP loci could be developed as markers for selection of WSSV-resistant varieties of Litopenaeus vannamei
关键词	Anti-lipopolysaccharide Factors (Alfs) Single Nucleotide Polymorphisms (Snps) White Spot Syndrome Virus (Wssv) Resistance Litopenaeus Vannamei
学科领域	Marine & Freshwater Biology ; Oceanography
DOI	10.1007/s00343-015-4010-4
收录类别	SCI
语种	英语
WOS记录号	WOS:000344541900003
引用统计	被引频次：11[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.qdio.ac.cn/handle/337002/24060
专题	实验海洋生物学重点实验室
通讯作者	Xiang, JH (reprint author), Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China.
作者单位	1.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Chinese Acad Sci, Inst Oceanol, Natl & Local Joint Engn Lab Ecol Mariculture, Qingdao 266071, Peoples R China
第一作者单位	实验海洋生物学重点实验室
推荐引用方式 GB/T 7714	Liu Jingwen,Yu Yang,Li Fuhua,et al. A new ALF from Litopenaeus vannamei and its SNPs related to WSSV resistance[J]. CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY,2014,32(6):1232-1247.
APA	Liu Jingwen,Yu Yang,Li Fuhua,Zhang Xiaojun,Xiang Jianhai,&Xiang, JH .(2014).A new ALF from Litopenaeus vannamei and its SNPs related to WSSV resistance.CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY,32(6),1232-1247.
MLA	Liu Jingwen,et al."A new ALF from Litopenaeus vannamei and its SNPs related to WSSV resistance".CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY 32.6(2014):1232-1247.

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