Positive selection in cilia-related genes may facilitate deep-sea adaptation of <i>Thermocollonia</i> jamsteci

doi:10.1016/j.scitotenv.2024.175358

	*Positive selection in cilia-related genes may facilitate deep-sea adaptation of Thermocollonia* jamsteci**
	Duan, Zelin 1,2,3,4; Wang, Jing1,3,4 ; Liu, Shuya 1,3,4; Xu, Qing 1,3,4,5; Chen, Hao6 ; Li, Chaolun1,6 ; Hui, Min 1,2,7; Chen, Nansheng 1,2,4,5
	2024-11-10
发表期刊	SCIENCE OF THE TOTAL ENVIRONMENT
ISSN	0048-9697
卷号	950 页码:13
通讯作者	Hui, Min([email protected]) ; Chen, Nansheng([email protected])
摘要	Deep-sea hydrothermal vents are characterized by high hydrostatic pressure, hypoxia, darkness and toxic substances. However, how organisms adapt to such extreme marine ecosystems remain poorly understood. We hypothesize that adaptive evolution plays an essential role in generating novelty for evolutionary adaptation to the deep-sea environment because adaptive evolution has been found to be critical for species origin and evolution. In this project, the chromosome-level genome of the deep-sea hydrothermal vent gastropod T. jamsteci was constructed for the first time to examine molecular mechanisms of its adaptation to the deep-sea environment. The genome size was large (2.54 Gb), ranking at the top of all species in the Vetigastropoda subclass, driven primarily by the bursts of transposable elements (TEs). The transposition of TEs may also trigger chromosomal changes including both inter-chromosomal fusions and intra-chromosomal activities involving chromosome inversions, rearrangements and fusions, as revealed by comparing the genomes of T. jamsteci and its closely related shallow-sea species Gibbula magus. Innovative changes including the expansion of the ABC transporter gene family that may facilitate detoxification, duplication of genes related to endocytosis, immunity, apoptosis, and anti-apoptotic domains that may help T. jamsteci fight against microbial pathogens, were identified. Furthermore, comparative analysis identified positive selection signals in a large number of genes including the hypoxia up-regulated protein 1, which is a chaperone that may promote adaptation of the T. jamsteci to hypoxic deepsea environments, hox2, Rx2, Pax6 and cilia-related genes BBS1, BBS2, BBS9 and RFX4. Notably, because of the critical importance of cilia and IFT in development, positive selection in ciliarelated genes may play a critical role in facilitating T. jamsteci to adapt to the high-pressure deep-sea ecosystem. Results from this study thus revealed important molecular clues that may facilitate further research on the adaptation of molluscs to deep-sea hydrothermal vents.
关键词	Thermocollonia jamsteci Comparative genomics Transposon burst Chromosome evolution Ciliary transport Deep-sea adaptive evolution
DOI	10.1016/j.scitotenv.2024.175358
收录类别	SCI
语种	英语
资助项目	Science and Technology Innovation Project of Laoshan Laboratory[LSKJ202203100]; Strategic Priority Research Program of Chinese Academy of Sciences[XDB42000000]; Taishan Scholar Project Special Fund; National Natural Science Foundation of China[42030407]; Marine S & T Fund of Shandong Province for Pilot National Laboratory for Marine Science and Technology (Qingdao)[2022QNLM030004]; Oceanographic Data Center, IOCAS
WOS研究方向	Environmental Sciences & Ecology
WOS类目	Environmental Sciences
WOS记录号	WOS:001294309600001
出版者	ELSEVIER
WOS关键词	JURASSIC MASS EXTINCTION ; GENOME-SIZE VARIATION ; TRANSPOSABLE ELEMENTS ; HOMEOBOX GENE ; EYE ; EVOLUTION ; PROVIDES ; SYSTEM ; INTEGRATION ; EXPRESSION
引用统计	被引频次：1[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.qdio.ac.cn/handle/337002/199595
专题	海洋生态与环境科学重点实验室海洋生物分类与系统演化实验室
通讯作者	Hui, Min; Chen, Nansheng
作者单位	1.Chinese Acad Sci, Inst Oceanol, CAS Key Lab Marine Ecol & Environm Sci, Qingdao 266071, Peoples R China 2.Laoshan Lab, Qingdao 266237, Peoples R China 3.Qingdao Marine Sci & Technol Ctr, Lab Marine Ecol & Environm Sci, Qingdao, Peoples R China 4.Chinese Acad Sci, Ctr Ocean Mega Sci, Qingdao 266071, Peoples R China 5.China Three Gorges Univ, Coll Basic Med Sci, Yichang 443000, Peoples R China 6.Chinese Acad Sci, Ctr Deep Sea Res, Inst Oceanol, Qingdao 266071, Peoples R China 7.Chinese Acad Sci, Inst Oceanol, Lab Marine Organism Taxon & Phylogeny, Qingdao Key Lab Marine Biodivers & Conservat, Qingdao 266071, Peoples R China
推荐引用方式 GB/T 7714	Duan, Zelin,Wang, Jing,Liu, Shuya,et al. Positive selection in cilia-related genes may facilitate deep-sea adaptation of Thermocollonia jamsteci[J]. SCIENCE OF THE TOTAL ENVIRONMENT,2024,950:13.
APA	Duan, Zelin.,Wang, Jing.,Liu, Shuya.,Xu, Qing.,Chen, Hao.,...&Chen, Nansheng.(2024).Positive selection in cilia-related genes may facilitate deep-sea adaptation of Thermocollonia jamsteci.SCIENCE OF THE TOTAL ENVIRONMENT,950,13.
MLA	Duan, Zelin,et al."Positive selection in cilia-related genes may facilitate deep-sea adaptation of Thermocollonia jamsteci".SCIENCE OF THE TOTAL ENVIRONMENT 950(2024):13.