Polysaccharides induce deep-sea <i>Lentisphaerae</i> strains to release chronic bacteriophages

doi:10.7554/eLife.92345

IOCAS-IR > 实验海洋生物学重点实验室

	*Polysaccharides induce deep-sea Lentisphaerae* strains to release chronic bacteriophages**
	Wang, Chong1,2,3,4 ; Zheng, Rikuan1,2,3,4 ; Zhang, Tianhang 1,2,3,4,5; Sun, Chaomin 1,2,3,4,5
	2024-08-29
发表期刊	ELIFE
ISSN	2050-084X
卷号	13 页码:20
通讯作者	Sun, Chaomin([email protected])
摘要	Viruses are ubiquitous in nature and play key roles in various ecosystems. Notably, some viruses (e.g. bacteriophage) exhibit alternative life cycles, such as chronic infections without cell lysis. However, the impact of chronic infections and their interactions with the host organisms remains largely unknown. Here, we found for the first time that polysaccharides induced the production of multiple temperate phages infecting two deep-sea Lentisphaerae strains (WC36 and zth2). Through physiological assays, genomic analysis, and transcriptomics assays, we found these bacteriophages were released via a chronic style without host cell lysis, which might reprogram host polysaccharide metabolism through the potential auxiliary metabolic genes. The findings presented here, together with recent discoveries made on the reprogramming of host energy-generating metabolisms by chronic bacteriophages, shed light on the poorly explored marine virus-host interaction and bring us closer to understanding the potential role of chronic viruses in marine ecosystems.
关键词	deep-sea virus polysaccharides bacteriophages auxiliary metabolic genes carbon cycle Viruses
DOI	10.7554/eLife.92345
收录类别	SCI
语种	英语
资助项目	NSFC Innovative Group[42221005]; NSFC Innovative Group Grant[2022QNLM030004-3]; NSFC Innovative Group Grant[LSKJ202203103]; Science and Technology Innovation Project of Laoshan Laboratory[92351301]; Major Research Plan of the National Natural Science Foundation[ZR2021ZD28]; Major Research Plan of the National Natural Science Foundation[ZR2023QD010]; Shandong Provincial Natural Science Foundation[XDA22050301]; Strategic Priority Research Program of the Chinese Academy of Sciences; Key Collaborative Research Program of the Alliance of International Science Organizations[tsqn202312264]; Taishan Scholars Program
WOS研究方向	Life Sciences & Biomedicine - Other Topics
WOS类目	Biology
WOS记录号	WOS:001326861300001
出版者	eLIFE SCIENCES PUBL LTD
WOS关键词	FILAMENTOUS PHAGE ; MARINE VIRUSES ; READ ALIGNMENT ; RESOURCE ; GENES ; CLASSIFICATION ; BACTERIA ; FEATURES ; DATABASE ; PROPHAGE
引用统计
文献类型	期刊论文
条目标识符	http://ir.qdio.ac.cn/handle/337002/199313
专题	实验海洋生物学重点实验室深海极端环境与生命过程研究中心
通讯作者	Sun, Chaomin
作者单位	1.Chinese Acad Sci, Inst Oceanol, CAS & Shandong Prov Key Lab Expt Marine Biol, Qingdao, Peoples R China 2.Chinese Acad Sci, Inst Oceanol, Ctr Deep Sea Res, Qingdao, Peoples R China 3.Qingdao Marine Sci & Technol Ctr, Lab Marine Biol & Biotechnol, Qingdao, Peoples R China 4.Chinese Acad Sci, Ctr Ocean Mega Sci, Qingdao, Peoples R China 5.Univ Chinese Acad Sci, Coll Earth Sci, Beijing, Peoples R China
推荐引用方式 GB/T 7714	Wang, Chong,Zheng, Rikuan,Zhang, Tianhang,et al. Polysaccharides induce deep-sea Lentisphaerae strains to release chronic bacteriophages[J]. ELIFE,2024,13:20.
APA	Wang, Chong,Zheng, Rikuan,Zhang, Tianhang,&Sun, Chaomin.(2024).Polysaccharides induce deep-sea Lentisphaerae strains to release chronic bacteriophages.ELIFE,13,20.
MLA	Wang, Chong,et al."Polysaccharides induce deep-sea Lentisphaerae strains to release chronic bacteriophages".ELIFE 13(2024):20.