Chromosome-level genome assemblies of two littorinid marine snails indicate genetic basis of intertidal adaptation and ancient karyotype evolved from bilaterian ancestors

doi:10.1093/gigascience/giae072

	Chromosome-level genome assemblies of two littorinid marine snails indicate genetic basis of intertidal adaptation and ancient karyotype evolved from bilaterian ancestors
	Wang, Yan-Shu 1,2,3; Li, Meng-Yu 1,2,3; Li, Yu-Long1,2 ; Li, Yu-Qiang1,2,3 ; Xue, Dong-Xiu1,2 ; Liu, Jin-Xian 1,2
	2024-09-25
发表期刊	GIGASCIENCE
ISSN	2047-217X
卷号	13 页码:10
通讯作者	Liu, Jin-Xian([email protected])
摘要	Living in the intertidal environment, littorinid snails are excellent models for understanding genetic mechanisms underlying adaptation to harsh fluctuating environments. Furthermore, the karyotypes of littorinid snails, with the same chromosome number as the presumed bilaterian ancestor, make them valuable for investigating karyotype evolution from the bilaterian ancestor to mollusks. Here, we generated high-quality, chromosome-scale genome assemblies for 2 littorinid marine snails, Littorina brevicula (927.94 Mb) and Littoraria sinensis (882.51 Mb), with contig N50 of 3.43 Mb and 2.31 Mb, respectively. Comparative genomic analyses identified 92 expanded gene families and 85 positively selected genes as potential candidates possibly associated with intertidal adaptation in the littorinid lineage, which were functionally enriched in stimulus responses, innate immunity, and apoptosis process regulation and might be involved in cellular homeostasis maintenance in stressful intertidal environments. Genome macrosynteny analyses indicated that 4 fissions and 4 fusions led to the evolution from the 17 presumed bilaterian ancestral chromosomes to the 17 littorinid chromosomes, implying that the littorinid snails have a highly conserved karyotype with the bilaterian ancestor. Based on the most parsimonious reconstruction of the common ancestral karyotype of scallops and littorinid snails, 3 chromosomal fissions and 1 chromosomal fusion from the bilaterian ancient linkage groups were shared by the bivalve scallop and gastropoda littorinid snails, indicating that the chromosome-scale ancient gene linkages were generally preserved in the mollusk genomes for over 500 million years. The highly conserved karyotype makes the littorinid snail genomes valuable resources for understanding early bilaterian evolution and biology.
关键词	littorinid chromosomal assembly intertidal adaptation karyotype evolution
DOI	10.1093/gigascience/giae072
收录类别	SCI
语种	英语
资助项目	National Natural Science Foundation of China[31970488]; National Natural Science Foundation of China[31972793]
WOS研究方向	Life Sciences & Biomedicine - Other Topics ; Science & Technology - Other Topics
WOS类目	Biology ; Multidisciplinary Sciences
WOS记录号	WOS:001322706200001
出版者	OXFORD UNIV PRESS
WOS关键词	MOLECULAR PHYLOGENY ; GASTROPODA ; TOLERANCE ; EVOLUTION ; ANNOTATION ; DIVERGENCE ; MECHANISMS ; ALIGNMENTS ; SOFTWARE ; DATABASE
引用统计
文献类型	期刊论文
条目标识符	http://ir.qdio.ac.cn/handle/337002/199259
专题	海洋生态与环境科学重点实验室
通讯作者	Liu, Jin-Xian
作者单位	1.Chinese Acad Sci, Inst Oceanol, CAS Key Lab Marine Ecol & Environm Sci, Qingdao 266071, Peoples R China 2.Qingdao Marine Sci & Technol Ctr, Lab Marine Ecol & Environm Sci, Qingdao 266237, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Wang, Yan-Shu,Li, Meng-Yu,Li, Yu-Long,et al. Chromosome-level genome assemblies of two littorinid marine snails indicate genetic basis of intertidal adaptation and ancient karyotype evolved from bilaterian ancestors[J]. GIGASCIENCE,2024,13:10.
APA	Wang, Yan-Shu,Li, Meng-Yu,Li, Yu-Long,Li, Yu-Qiang,Xue, Dong-Xiu,&Liu, Jin-Xian.(2024).Chromosome-level genome assemblies of two littorinid marine snails indicate genetic basis of intertidal adaptation and ancient karyotype evolved from bilaterian ancestors.GIGASCIENCE,13,10.
MLA	Wang, Yan-Shu,et al."Chromosome-level genome assemblies of two littorinid marine snails indicate genetic basis of intertidal adaptation and ancient karyotype evolved from bilaterian ancestors".GIGASCIENCE 13(2024):10.