Light-Broadened Faradaic Regime of Organic Electrochemical Transistors for Accelerated Amperometric Biodetection

doi:10.1002/adfm.202409153

	Light-Broadened Faradaic Regime of Organic Electrochemical Transistors for Accelerated Amperometric Biodetection
	Ju, Peng1,2 ; Jiang, Xingwu 3,4; Xu, Yi-Tong 4; Hu, Jin 4; Chi, Jingtian 1,2; Jiang, Tiantong 1,2; Lu, Zhaoxia 5,6; Zhai, Xiaofan 3,5; Zhao, Wei-Wei 4
	2024-08-29
发表期刊	ADVANCED FUNCTIONAL MATERIALS
ISSN	1616-301X
页码	7
通讯作者	Zhai, Xiaofan([email protected]) ; Zhao, Wei-Wei([email protected])
摘要	Faradaic-mode organic electrochemical transistors (OECT) are promising but usually need hundreds of millivolts to sustain redox reactions. Decrease or even removal of the voltage penalty is highly desirable. Herein, the Faradic regime of the OECT is broadened toward zero bias by integrating a p-n heterojunction of Cu2S-diethylenetriamine (DETA)-CdS for efficient photogating of poly(3,4-ethylenedioxythiophene): poly(styrene sulfonate) channel. Upon light illumination, it is found that an obvious Faradaic process is evolved at the gate/electrolyte interface under zero gate bias, suggesting the potential of sensitive amperometric biodetection with enhanced signal resolution. At the Cu2S-DETA-CdS/liquid interface, a biosensing process is introduced, combining with a DNA walker and enzymatic biocatalytic precipitation to produce a target-dependent diffusion barrier, modulating the amperometric output with enhanced signal variations under light irradiation compared to that in the dark. The proposed system achieves the desired analytical performance for representative target miRNA-10b with a low detection limit of 0.21 fM. This work features a light-mediated OECT device with enhanced signal resolution and provides new operational paradigms and insights for novel optoelectronics interfacing with biological systems. The organic electrochemical transistor (OECT) is rationally integrated with a p-n heterojunction of Cu2S-DETA-CdS with highly efficient light-electric conversion. The Faradaic regime of the OECT can thus be broadened toward zero gate bias under light illumination. Amperometric output with enhanced signal resolution can be obtained with the DNA walker and enzymatic biocatalytic precipitation. image
关键词	amperometric detection DNA Walker faradic regime organic electrochemical transistors p-n heterojunction
DOI	10.1002/adfm.202409153
收录类别	SCI
语种	英语
资助项目	National Natural Science Foundation of China[42376204]; Basic Scientific Fund for National Public Research Institutes of China[2019Y03]; Open Fund of Shandong Key Laboratory of Marine Ecological Environment and Disaster Prevention and Mitigation[202203]; Young Elite Scientists Sponsorship Program by CAST[YESS20210201]
WOS研究方向	Chemistry ; Science & Technology - Other Topics ; Materials Science ; Physics
WOS类目	Chemistry, Multidisciplinary ; Chemistry, Physical ; Nanoscience & Nanotechnology ; Materials Science, Multidisciplinary ; Physics, Applied ; Physics, Condensed Matter
WOS记录号	WOS:001303088000001
出版者	WILEY-V C H VERLAG GMBH
WOS关键词	DNA
引用统计	被引频次：1[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.qdio.ac.cn/handle/337002/198186
专题	海洋环境腐蚀与生物污损重点实验室
通讯作者	Zhai, Xiaofan; Zhao, Wei-Wei
作者单位	1.Minist Nat Resources, Inst Oceanog 1, Key Lab Marine Ecoenvironm Sci & Technol, 6 Xianxialing Rd, Qingdao 266061, Peoples R China 2.Minist Nat Resources, Inst Oceanog 1, Observat & Res Stn Bohai Ecocorridor Marine Biores, 6 Xianxialing Rd, Qingdao 266061, Peoples R China 3.Chinese Acad Sci, Inst Oceanol, CAS Key Lab Marine Environm Corros & Biofouling, 7 Nanhai Rd, Qingdao 266071, Peoples R China 4.Nanjing Univ, Sch Chem & Chem Engn, State Key Lab Analyt Chem Life Sci, Nanjing 210023, Peoples R China 5.Guangxi Acad Sci, Inst Marine Corros & Protect, 98 Dalin Rd, Nanning 530007, Peoples R China 6.Guangxi Univ, Coll Chem & Chem Engn, Nanning 530004, Peoples R China
推荐引用方式 GB/T 7714	Ju, Peng,Jiang, Xingwu,Xu, Yi-Tong,et al. Light-Broadened Faradaic Regime of Organic Electrochemical Transistors for Accelerated Amperometric Biodetection[J]. ADVANCED FUNCTIONAL MATERIALS,2024:7.
APA	Ju, Peng.,Jiang, Xingwu.,Xu, Yi-Tong.,Hu, Jin.,Chi, Jingtian.,...&Zhao, Wei-Wei.(2024).Light-Broadened Faradaic Regime of Organic Electrochemical Transistors for Accelerated Amperometric Biodetection.ADVANCED FUNCTIONAL MATERIALS,7.
MLA	Ju, Peng,et al."Light-Broadened Faradaic Regime of Organic Electrochemical Transistors for Accelerated Amperometric Biodetection".ADVANCED FUNCTIONAL MATERIALS (2024):7.