Involvement of clustered oyster Wnt genes in gut formation

IOCAS-IR

	Involvement of clustered oyster Wnt genes in gut formation
	Liu J(刘俊); Xu F(许飞); Ji P(纪鹏); Li L(李莉); Zhang GF(张国范)
发表期刊	Journal of Oceanology and Limnology
ISSN	2096-5508
	2018-09-15
出版年	2018
卷号	v.36 期号:05 页码:290-296
文献类型	CNKI期刊论文
摘要	Genes encoding Wnt ligands play important roles in organ development. The Wnt10-Wnt6-Wnt1-Wnt9 cluster widely presents in many metazoan genomes, indicating the importance of gene arrangement. Hypothesis has been proposed that they may be coordinately regulated. However, few expression correlations were identified in model animals. We analyzed the tissue expression pattern of clustered oyster Wnt10, Wnt6, Wnt1, and Wnt9 a genes in this study. The results indicated the highest expression level in adult gut system of these clustered W nt genes, except for Wnt6, which had highest expression in mantle. Further whole-mount immunofluorescence assay indicated that Wnt6 protein was restricted to gut region in oyster larvae. These results suggest the possible important role of the W nt10-Wnt6-Wnt1-Wnt9 cluster in oyster gut formation.
关键词	gene cluster tissue distribution digestive gland immunofl uorescence Crassostrea gigas
CNKI专辑号	A;
CNKI专辑名称	基础科学;
CNKI专题号	A006;
CNKI专题名称	生物学;
分类号	Q953
收录类别	中科院核心 ; 中科院扩展
语种	英文;
资助项目(基金）	Supported by the National Natural Science Foundation of China(Nos.41776152,31402285,31530079) ; the Scientific and Technological Innovation Project supported by Qingdao National Laboratory for Marine Science and Technology(No.2015ASKJ02) ; the earmarked fund for Modern Agro-industry Technology Research System(No.CARS-49)
文献类型	CNKI期刊论文
条目标识符	http://ir.qdio.ac.cn/handle/337002/188811
专题	中国科学院海洋研究所
作者单位	1.KeyLaboratoryofExperimentalMarineBiology,InstituteofOceanology,ChineseAcademyofSciences 2.UniversityofChineseAcademyofSciences 3.National&LocalJointEngineeringLaboratoryofEcologicalMariculture,InstituteofOceanology,ChineseAcademyofSciences 4.LaboratoryforMarineBiologyandBiotechnology,QingdaoNationalLaboratoryforMarineScienceandTechnology 5.LaboratoryforMarineFisheriesandAquaculture,QingdaoNationalLaboratoryforMarineScienceandTechnology
推荐引用方式 GB/T 7714	Liu J,Xu F,Ji P,et al. Involvement of clustered oyster Wnt genes in gut formation. 2018.