Evolutionary dynamics of the Wnt gene family: implications for lophotrochozoans

IOCAS-IR

	Evolutionary dynamics of the Wnt gene family: implications for lophotrochozoans
	Liu J(刘俊); Xu F(许飞); Ji P(纪鹏); Li L(李莉); Zhang GF(张国范)
发表期刊	Journal of Oceanology and Limnology
ISSN	2096-5508
	2018-09-15
出版年	2018
卷号	v.36 期号:05 页码:264-274
文献类型	CNKI期刊论文
摘要	Genes encoding Wnt ligands, which have important roles in cell communication and organ development, are restricted to multicellular animals. We systematically studied W nt genes from eumetazoan genomes, with emphasis on the poorly studied superphylum Lophotrochozoa(four annelids, seven mollusks, eight platyhelminths, one bdelloid rotifer, and one brachiopod species). Between 3 and 39 W nt loci were identified in each genome, and the protostome-specific loss of Wnt3 genes was confirmed. We identified gastropod-specific loss of Wnt8, refining the previously proposed mollusk-specific loss. Some duplicated Wnt genes belonging to a same subfamily or closely related subfamilies showed tandem distribution in the lophotrochozoan genomes, indicating tandem duplication events during Wnt family evolution. Members of the conserved Wnt10-Wnt6-Wnt1-Wnt9 cluster showed highly correlated expression patterns over time in two assayed lophotrochozoans, the oyster C rassostrea gigas and the brachiopod L ingula anatina, reflecting the possible similar function of the clustered W nt genes.
关键词	phylogeny gene cluster time-course expression tissue distribution
CNKI专辑号	A;
CNKI专辑名称	基础科学;
CNKI专题号	A006;
CNKI专题名称	生物学;
分类号	Q75
收录类别	中科院核心 ; 中科院扩展
语种	英文;
资助项目(基金）	Supported by the National Natural Science Foundation of China(Nos.31402285,31530079) ; the Scientific and Technological Innovation Project financially supported by the Qingdao National Laboratory for Marine Science and Technology(No.2015ASKJ02) ; the earmarked fund for Modern Agro-Industry Technology Research System(No.CARS-48)
文献类型	CNKI期刊论文
条目标识符	http://ir.qdio.ac.cn/handle/337002/188810
专题	中国科学院海洋研究所
作者单位	1.KeyLaboratoryofExperimentalMarineBiology,InstituteofOceanology,ChineseAcademyofSciences 2.UniversityofChineseAcademyofSciences 3.National&LocalJointEngineeringLaboratoryofEcologicalMariculture,InstituteofOceanology,ChineseAcademyofSciences 4.LaboratoryforMarineBiologyandBiotechnology,QingdaoNationalLaboratoryforMarineScienceandTechnology 5.LaboratoryforMarineFisheriesandAquaculture,QingdaoNationalLaboratoryforMarineScienceandTechnology
推荐引用方式 GB/T 7714	Liu J,Xu F,Ji P,et al. Evolutionary dynamics of the Wnt gene family: implications for lophotrochozoans. 2018.