Effects of dissolved oxygen on intestinal bacterial community and immunity of Atlantic salmon Salmo salar

IOCAS-IR

	Effects of dissolved oxygen on intestinal bacterial community and immunity of Atlantic salmon Salmo salar
	Shihong XU ; Yanfeng WANG ; Caixia GAO ; Sarath ; BABU V ; Jun LI ; Qinghua LIU ; Zhizhong XIAO ; Yingxuan XU ; Chunyan ZHAO; Li LIN ; Liang CHI
发表期刊	Journal of Oceanology and Limnology
ISSN	2096-5508
	2023-01-15
出版年	2023
卷号	v.41 期号:01 页码:366-377
文献类型	CNKI期刊论文
摘要	Dissolved oxygen(DO) is one of most important factors which affect wide range physiologic features of including immune responses and intestinal bacterial community.However,the underlying mechanisms remain enigmatic.To address this question,the intestinal bacterial community compositions and the immune features of Atlantic salmon(Salmo salar) grown in recirculating aquaculture systems(RAS) were characterized.Fish were reared under different DO saturation levels,e.g.,200% saturation named high group(H),100% saturation named control group(CK),and 60% saturation named lower group(L).Large variations in the operational taxonomic units(OTUs) frequency distribution for the intestinal bacterial community of Atlantic salmon were observed.The intestinal bacterial community of all groups was dominated mainly by three phyla,e.g.,Proteobacteria.Firmicutes,and Bacteroidetes.Interestingly,Acinetobacter baumannii,an opportunistic pathogen of salmon was increased significantly in L group.We further monitored the immunity features of fish under different DO levels.The results show that leucocyte number,cortisol level,the expressions of interleukin-1β(IL-1β),Toll-like receptor 4(TLR4),and nucleotide-binding oligomerization domain like protein 2(NOD2) were higher at significant levels in the L group than those in the other two groups.TLR4 and NOD2 are usually related with the bacterial infections;therefore,it is reasonable to believe that the stronger immune responses observed in the L group might be related with the higher abundance of A.baumannii in the inte stine of Atlantic salmon.Overall,these findings demonstrated that low DO level may induce stronger immunity responses in Atlantic salmon.
关键词	Atlantic salmon dissolved oxygen(DO) immune responses microbiota intestine
CNKI专辑号	A;D;
CNKI专辑名称	基础科学;农业科技;
CNKI专题号	D052;
CNKI专题名称	水产和渔业;
分类号	S917.4
收录类别	中科院核心 ; 中科院扩展
语种	英文;
资助项目(基金）	Supported by the Shandong Province Key Research and Invention Program (No. 2017CXGC010K) ; the China Agriculture Research System (No. CARS-47) ; the National Key Research and Development Program (No. 2018YFD0901204) ; the National Infrastructure of Fishery Germplasm Resource (No. 2019DKA30470) ; the Marine S&T Fund of Shandong Province for Pilot National Laboratory for Marine Science and Technology (Qingdao)(No. 2018SDKJ0502-2) ; the National Natural Science Foundation of China (Nos. 31872606, 31572657, U1701233, 31402283, 31802319) ; the Department of Agriculture and Rural Areas of Guangdong Province (No. KA1911101) ; the Natural Science Foundation of Shandong Province (No. ZR2018BC053) ; the Agricultural Application Technology Innovation Project of Shandong Province in 2018/2019 (No. SD2019YY011) ; the Shandong Province Major Scientific and Technological Innovation Projects (No. 2019JZZY020710)
文献类型	CNKI期刊论文
条目标识符	http://ir.qdio.ac.cn/handle/337002/187205
专题	中国科学院海洋研究所
作者单位	1.DepartmentofAquaticAnimalMedicine,CollegeofFisheries,HuazhongAgriculturalUniversity 2.CASKeyLaboratoryofExperimentalMarineBiology,InstituteofOceanology,ChineseAcademyofSciences 3.LaboratoryAnimalandComparativeMedicineTeam,StateKeyLaboratoryofVeterinaryBiotechnology,HarbinVeterinaryResearchInstitute,ChineseAcademyofAgriculturalSciences(CAAS) 4.GuangdongProvincialWaterEnvironmentandAquaticProductsSecurityEngineeringTechnologyResearchCenter,GuangzhouKeyLaboratoryofAquaticAnimalDiseasesandWaterfowlBreeding,ZhongkaiUniversityofAgricultureandEngineering 5.UniversityCollegeLondon 6.SchoolofMarineScienceandEngineering,QingdaoAgriculturalUniversity 7.CollegeofVeterinaryMedicine,QingdaoAgriculturalUniversity
推荐引用方式 GB/T 7714	Shihong XU,Yanfeng WANG,Caixia GAO,et al. Effects of dissolved oxygen on intestinal bacterial community and immunity of Atlantic salmon Salmo salar. 2023.