Institutional Repository of Key Laboratory of Marine Ecology & Environmental Sciences, CAS
Response and adaptation mechanisms of Apostichopus japonicus to single and combined anthropogenic stresses of polystyrene microplastics or cadmium | |
Li, Kehan1,2,3,5; Wang, Fayuan5; Liu, Shuai6; Cheng, Xiaochen1,2,3,5; Xu, Jialei4; Liu, Xiao4; Zhang, Libin1,2,3 | |
2024-07-01 | |
发表期刊 | MARINE POLLUTION BULLETIN |
ISSN | 0025-326X |
卷号 | 204页码:12 |
通讯作者 | Zhang, Libin([email protected]) |
摘要 | Microplastics (MPs) have become pervasive in marine ecosystems, exerting detrimental effects on marine life. The concurrent presence and interaction of MPs and heavy metals in aquatic environments could engender more insidious toxicological impacts. This study aimed to elucidate the potential impacts and underlying mechanisms of polystyrene microplastics (PS-MPs), cadmium (Cd), and their combined stress (MPs-Cd) on sea cucumbers (Apostichopus japonicus). It focused on the growth, Cd bioaccumulation, oxidative stress responses, immunoenzymatic activities, and metabolic profiles, specifically considering PS-MPs sizes preferentially ingested by these organisms. The high-dose MPs (MH) treatment group exhibited an increase in cadmium bioavailability within the sea cucumbers. Exposure to PS-MPs or Cd triggered the activation of antioxidant defenses and immune responses. PS-MPs and Cd exhibited a synergistic effect on lysozyme (LZM) activity. A total of 149, 316, 211, 197, 215, 619, 434, and 602 differentially expressed metabolites were identified, distinguishing the low-dose MPs (ML), high-dose MPs (MH), low-dose Cd (LCd), low-dose MPs and low-dose Cd (MLLCd), high-dose MPs and low-dose Cd (MHLCd), high-dose Cd (HCd), low-dose MPs and high-dose Cd (MLHCd), high-dose MPs and high-dose Cd (MHHCd) groups, respectively. Metabolomic analyses revealed disruptions in lipid metabolism, nervous system function, signal transduction, and transport and catabolism pathways following exposure to PSMPs, Cd, and MPs-Cd. Correlation analyses among key differentially expressed metabolites (DEMs) underscored the interregulation among these metabolic pathways. These results offer new perspectives on the distinct and synergistic toxicological impacts of microplastics and cadmium on aquatic species, highlighting the complex interplay between environmental contaminants and their effects on marine life. |
关键词 | Polystyrene microplastics (PS-MPs) Cadmium (cd) Combined anthropogenic stresses Metabolomics Apostichopus japonicus |
DOI | 10.1016/j.marpolbul.2024.116519 |
收录类别 | SCI |
语种 | 英语 |
资助项目 | National Key Research and Devel- opment Program of China[2023YFD2401105] |
WOS研究方向 | Environmental Sciences & Ecology ; Marine & Freshwater Biology |
WOS类目 | Environmental Sciences ; Marine & Freshwater Biology |
WOS记录号 | WOS:001263752600001 |
出版者 | PERGAMON-ELSEVIER SCIENCE LTD |
WOS关键词 | HEAVY-METAL POLLUTION ; TRACE-METALS ; SEA ; BIOACCUMULATION ; ACCUMULATION ; ADSORPTION ; SEDIMENTS ; WATER |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.qdio.ac.cn/handle/337002/186306 |
专题 | 海洋生态与环境科学重点实验室 |
通讯作者 | Zhang, Libin |
作者单位 | 1.Chinese Acad Sci, Inst Oceanol, CAS Key Lab Marine Ecol & Environm Sci, Qingdao 266071, Peoples R China 2.Qingdao Marine Sci & Technol Ctr, Lab Marine Ecol & Environm Sci, Qingdao 266237, Peoples R China 3.Chinese Acad Sci, Inst Oceanol, CAS Engn Lab Marine Ranching, Qingdao 266071, Peoples R China 4.Zhongke Tonghe Shandong Ocean Technol Co Ltd, Dongying 257200, Peoples R China 5.Qingdao Univ Sci & Technol, Coll Environm & Safety Engn, Qingdao 266042, Peoples R China 6.Binzhou Ocean Dev Res Inst, Binzhou 256600, Peoples R China |
第一作者单位 | 海洋生态与环境科学重点实验室; 中国科学院海洋研究所 |
通讯作者单位 | 海洋生态与环境科学重点实验室; 中国科学院海洋研究所 |
推荐引用方式 GB/T 7714 | Li, Kehan,Wang, Fayuan,Liu, Shuai,et al. Response and adaptation mechanisms of Apostichopus japonicus to single and combined anthropogenic stresses of polystyrene microplastics or cadmium[J]. MARINE POLLUTION BULLETIN,2024,204:12. |
APA | Li, Kehan.,Wang, Fayuan.,Liu, Shuai.,Cheng, Xiaochen.,Xu, Jialei.,...&Zhang, Libin.(2024).Response and adaptation mechanisms of Apostichopus japonicus to single and combined anthropogenic stresses of polystyrene microplastics or cadmium.MARINE POLLUTION BULLETIN,204,12. |
MLA | Li, Kehan,et al."Response and adaptation mechanisms of Apostichopus japonicus to single and combined anthropogenic stresses of polystyrene microplastics or cadmium".MARINE POLLUTION BULLETIN 204(2024):12. |
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