IOCAS-IR  > 海洋生态与环境科学重点实验室
Response and adaptation mechanisms of Apostichopus japonicus to single and combined anthropogenic stresses of polystyrene microplastics or cadmium
Li, Kehan1,2,3,5; Wang, Fayuan5; Liu, Shuai6; Cheng, Xiaochen1,2,3,5; Xu, Jialei4; Liu, Xiao4; Zhang, Libin1,2,3
2024-07-01
发表期刊MARINE POLLUTION BULLETIN
ISSN0025-326X
卷号204页码:12
通讯作者Zhang, Libin([email protected])
摘要Microplastics (MPs) have become pervasive in marine ecosystems, exerting detrimental effects on marine life. The concurrent presence and interaction of MPs and heavy metals in aquatic environments could engender more insidious toxicological impacts. This study aimed to elucidate the potential impacts and underlying mechanisms of polystyrene microplastics (PS-MPs), cadmium (Cd), and their combined stress (MPs-Cd) on sea cucumbers (Apostichopus japonicus). It focused on the growth, Cd bioaccumulation, oxidative stress responses, immunoenzymatic activities, and metabolic profiles, specifically considering PS-MPs sizes preferentially ingested by these organisms. The high-dose MPs (MH) treatment group exhibited an increase in cadmium bioavailability within the sea cucumbers. Exposure to PS-MPs or Cd triggered the activation of antioxidant defenses and immune responses. PS-MPs and Cd exhibited a synergistic effect on lysozyme (LZM) activity. A total of 149, 316, 211, 197, 215, 619, 434, and 602 differentially expressed metabolites were identified, distinguishing the low-dose MPs (ML), high-dose MPs (MH), low-dose Cd (LCd), low-dose MPs and low-dose Cd (MLLCd), high-dose MPs and low-dose Cd (MHLCd), high-dose Cd (HCd), low-dose MPs and high-dose Cd (MLHCd), high-dose MPs and high-dose Cd (MHHCd) groups, respectively. Metabolomic analyses revealed disruptions in lipid metabolism, nervous system function, signal transduction, and transport and catabolism pathways following exposure to PSMPs, Cd, and MPs-Cd. Correlation analyses among key differentially expressed metabolites (DEMs) underscored the interregulation among these metabolic pathways. These results offer new perspectives on the distinct and synergistic toxicological impacts of microplastics and cadmium on aquatic species, highlighting the complex interplay between environmental contaminants and their effects on marine life.
关键词Polystyrene microplastics (PS-MPs) Cadmium (cd) Combined anthropogenic stresses Metabolomics Apostichopus japonicus
DOI10.1016/j.marpolbul.2024.116519
收录类别SCI
语种英语
资助项目National Key Research and Devel- opment Program of China[2023YFD2401105]
WOS研究方向Environmental Sciences & Ecology ; Marine & Freshwater Biology
WOS类目Environmental Sciences ; Marine & Freshwater Biology
WOS记录号WOS:001263752600001
出版者PERGAMON-ELSEVIER SCIENCE LTD
WOS关键词HEAVY-METAL POLLUTION ; TRACE-METALS ; SEA ; BIOACCUMULATION ; ACCUMULATION ; ADSORPTION ; SEDIMENTS ; WATER
引用统计
文献类型期刊论文
条目标识符http://ir.qdio.ac.cn/handle/337002/186306
专题海洋生态与环境科学重点实验室
通讯作者Zhang, Libin
作者单位1.Chinese Acad Sci, Inst Oceanol, CAS Key Lab Marine Ecol & Environm Sci, Qingdao 266071, Peoples R China
2.Qingdao Marine Sci & Technol Ctr, Lab Marine Ecol & Environm Sci, Qingdao 266237, Peoples R China
3.Chinese Acad Sci, Inst Oceanol, CAS Engn Lab Marine Ranching, Qingdao 266071, Peoples R China
4.Zhongke Tonghe Shandong Ocean Technol Co Ltd, Dongying 257200, Peoples R China
5.Qingdao Univ Sci & Technol, Coll Environm & Safety Engn, Qingdao 266042, Peoples R China
6.Binzhou Ocean Dev Res Inst, Binzhou 256600, Peoples R China
第一作者单位海洋生态与环境科学重点实验室;  中国科学院海洋研究所
通讯作者单位海洋生态与环境科学重点实验室;  中国科学院海洋研究所
推荐引用方式
GB/T 7714
Li, Kehan,Wang, Fayuan,Liu, Shuai,et al. Response and adaptation mechanisms of Apostichopus japonicus to single and combined anthropogenic stresses of polystyrene microplastics or cadmium[J]. MARINE POLLUTION BULLETIN,2024,204:12.
APA Li, Kehan.,Wang, Fayuan.,Liu, Shuai.,Cheng, Xiaochen.,Xu, Jialei.,...&Zhang, Libin.(2024).Response and adaptation mechanisms of Apostichopus japonicus to single and combined anthropogenic stresses of polystyrene microplastics or cadmium.MARINE POLLUTION BULLETIN,204,12.
MLA Li, Kehan,et al."Response and adaptation mechanisms of Apostichopus japonicus to single and combined anthropogenic stresses of polystyrene microplastics or cadmium".MARINE POLLUTION BULLETIN 204(2024):12.
条目包含的文件
条目无相关文件。
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Li, Kehan]的文章
[Wang, Fayuan]的文章
[Liu, Shuai]的文章
百度学术
百度学术中相似的文章
[Li, Kehan]的文章
[Wang, Fayuan]的文章
[Liu, Shuai]的文章
必应学术
必应学术中相似的文章
[Li, Kehan]的文章
[Wang, Fayuan]的文章
[Liu, Shuai]的文章
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。