Dual Engine Boosts Organic Photoelectrochemical Transistor for Enhanced Modulation and Bioanalysis

doi:10.1021/acs.analchem.4c01369

	Dual Engine Boosts Organic Photoelectrochemical Transistor for Enhanced Modulation and Bioanalysis
	Jiang, Xing-Wu 1,2; Ju, Peng5 ; Li, Zheng 2; Kou, Bo-Han 2; Zhai, Xiaofan 3; Chen, Feng-Zao 4; Zhu, Yuan-Cheng 2; Xu, Yi-Tong 2; Lu, Zhaoxia 1,6; Zhao, Wei-Wei 2
	2024-04-19
发表期刊	ANALYTICAL CHEMISTRY
ISSN	0003-2700
卷号	96 期号:17 页码:6847-6852
通讯作者	Ju, Peng([email protected]) ; Xu, Yi-Tong([email protected]) ; Lu, Zhaoxia([email protected]) ; Zhao, Wei-Wei([email protected])
摘要	Organic photoelectrochemical transistor (OPECT) has shown substantial potential in the development of next-generation bioanalysis yet is limited by the either-or situation between the photoelectrode types and the channel types. Inspired by the dual-photoelectrode systems, we propose a new architecture of dual-engine OPECT for enhanced signal modulation and its biosensing application. Exemplified by incorporating the CdS/Bi2S3 photoanode and Cu2O photocathode within the gate-source circuit of Ag/AgCl-gated poly(3,4-ethylenedioxythiophene):poly(styrenesulfonate) (PEDOT:PSS) channel, the device shows enhanced modulation capability and larger transconductance (g(m)) against the single-photoelectrode ones. Moreover, the light irritation upon the device effectively shifts the peak value of g(m) to zero gate voltage without degradation and generates larger current steps that are advantageous for the sensitive bioanalysis. Based on the as-developed dual-photoelectrode OPECT, target-mediated recycling and etching reactions are designed upon the CdS/Bi2S3, which could result in dual signal amplification and realize the sensitive microRNA-155 biodetection with a linear range from 1 fM to 100 pM and a lower detection limit of 0.12 fM.
DOI	10.1021/acs.analchem.4c01369
收录类别	SCI
语种	英语
资助项目	National Natural Science Foundation of China[42376204]; National Natural Science Foundation of China[22204118]; National Natural Science Foundation of China[22104053]; National Natural Science Foundation of China[202203]; Open Fund of Shandong Key Laboratory of Marine Ecological Environment and Disaster Prevention[2019Y03]; Basic Scientific Fund for National Public Research Institutes of China
WOS研究方向	Chemistry
WOS类目	Chemistry, Analytical
WOS记录号	WOS:001242291400001
出版者	AMER CHEMICAL SOC
引用统计	被引频次：5[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.qdio.ac.cn/handle/337002/186030
专题	海洋环境腐蚀与生物污损重点实验室
通讯作者	Ju, Peng; Xu, Yi-Tong; Lu, Zhaoxia; Zhao, Wei-Wei
作者单位	1.Guangxi Univ, Coll Chem & Chem Engn, Nanning 530004, Peoples R China 2.Nanjing Univ, Sch Chem & Chem Engn, State Key Lab Analyt Chem Life Sci, Nanjing 210023, Peoples R China 3.Chinese Acad Sci, Inst Oceanol, CAS Key Lab Marine Environm Corros & Biofouling, Qingdao 266071, Peoples R China 4.Taizhou Univ, Sch Pharmaceut & Chem Engn, Taizhou 318000, Peoples R China 5.Minist Nat Resources, Inst Oceanog 1, Marine Bioresource & Environm Res Ctr, Key Lab Marine Ecoenvironm Sci & Technol, Qingdao 266061, Peoples R China 6.Guangxi Acad Sci, Inst Marine Corros & Protect, Nanning 530007, Peoples R China
推荐引用方式 GB/T 7714	Jiang, Xing-Wu,Ju, Peng,Li, Zheng,et al. Dual Engine Boosts Organic Photoelectrochemical Transistor for Enhanced Modulation and Bioanalysis[J]. ANALYTICAL CHEMISTRY,2024,96(17):6847-6852.
APA	Jiang, Xing-Wu.,Ju, Peng.,Li, Zheng.,Kou, Bo-Han.,Zhai, Xiaofan.,...&Zhao, Wei-Wei.(2024).Dual Engine Boosts Organic Photoelectrochemical Transistor for Enhanced Modulation and Bioanalysis.ANALYTICAL CHEMISTRY,96(17),6847-6852.
MLA	Jiang, Xing-Wu,et al."Dual Engine Boosts Organic Photoelectrochemical Transistor for Enhanced Modulation and Bioanalysis".ANALYTICAL CHEMISTRY 96.17(2024):6847-6852.