Five new verrucosidin derivatives from Penicillium polonicum, a deep-sea cold-seep sediment isolated fungus

doi:10.1016/j.fitote.2022.105387

IOCAS-IR > 实验海洋生物学重点实验室

	Five new verrucosidin derivatives from Penicillium polonicum, a deep-sea cold-seep sediment isolated fungus
	Li, Yan-He1,2,3,4 ; Yang, Sui-Qun 1,2,3; Li, Xiao-Ming 1,2,3; Li, Xin1,2,3 ; Wang, Bin-Gui1,2,3,4,5 ; Li, Honglei1,2,3
	2023-03-01
发表期刊	FITOTERAPIA
ISSN	0367-326X
卷号	165 页码:7
通讯作者	Wang, Bin-Gui() ; Li, Honglei([email protected])
摘要	Five new verrucosidin derivatives, poloncosidins G-K (1-5), were isolated from the deep sea cold-seep sediment-derived fungus Penicillium polonicum CS-252. Their planar structures were elucidated by discreet analysis of the NMR spectroscopic and HRESIMS spectrometric data. The absolute configurations of compounds 1-5 were deduced from the combination of the modified Mosher's method and quantum chemical calculations of their ECD and NMR (with DP4+ probability analysis) data. The antimicrobial activities against several human-and aquatic-pathogenic bacteria of all the isolated compounds were evaluated and the structure-bioactivity relationship was briefly discussed.
关键词	Verrucosidin derivatives Penicillium polonicum Cold-seep-derived fungus
DOI	10.1016/j.fitote.2022.105387
收录类别	SCI
语种	英语
WOS研究方向	Pharmacology & Pharmacy
WOS类目	Chemistry, Medicinal ; Pharmacology & Pharmacy
WOS记录号	WOS:000918870100001
出版者	ELSEVIER
引用统计	被引频次：4[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.qdio.ac.cn/handle/337002/183341
专题	实验海洋生物学重点实验室
通讯作者	Wang, Bin-Gui; Li, Honglei
作者单位	1.Chinese Acad Sci, CAS, Inst Oceanol, Nanhai Rd 7, Qingdao 266071, Peoples R China 2.Chinese Acad Sci, Inst Oceanol, Shandong Prov Key Lab Expt Marine Biol, Nanhai Rd 7, Qingdao 266071, Peoples R China 3.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Biol & Biotechnol, Wenhai Rd 1, Qingdao 266237, Peoples R China 4.Univ Chinese Acad Sci, Coll Marine Sci, Yuquan Rd 19A, Beijing 100049, Peoples R China 5.Chinese Acad Sci, Ctr Ocean Mega Sci, Nanhai Rd 7, Qingdao 266071, Peoples R China
第一作者单位	中国科学院海洋研究所
通讯作者单位	中国科学院海洋研究所
推荐引用方式 GB/T 7714	Li, Yan-He,Yang, Sui-Qun,Li, Xiao-Ming,et al. Five new verrucosidin derivatives from Penicillium polonicum, a deep-sea cold-seep sediment isolated fungus[J]. FITOTERAPIA,2023,165:7.
APA	Li, Yan-He,Yang, Sui-Qun,Li, Xiao-Ming,Li, Xin,Wang, Bin-Gui,&Li, Honglei.(2023).Five new verrucosidin derivatives from Penicillium polonicum, a deep-sea cold-seep sediment isolated fungus.FITOTERAPIA,165,7.
MLA	Li, Yan-He,et al."Five new verrucosidin derivatives from Penicillium polonicum, a deep-sea cold-seep sediment isolated fungus".FITOTERAPIA 165(2023):7.