Astaxanthin production from the microalga Haematococcus lacustris with a dual substrate mixotrophy strategy

doi:10.1002/biot.202300095

IOCAS-IR > 实验海洋生物学重点实验室

	Astaxanthin production from the microalga Haematococcus lacustris with a dual substrate mixotrophy strategy
	Khazi, Mahammed Ilyas 1; Liaqat, Fakhra 1; Gu, Wenhui 2; Mohamed, Badr 3; Zhu, Daochen 4; Li, Jian 1
	2023-06-28
发表期刊	BIOTECHNOLOGY JOURNAL
ISSN	1860-6768
页码	11
通讯作者	Li, Jian([email protected])
摘要	This study investigates the development of dual-substrate mixotrophy strategy to cultivate the microalga Haematococcus lacustris for astaxanthin production. The influence of different concentrations of acetate and pyruvate on biomass productivity was first assessed individually, and then both substrates were used together to improve biomass growth in the green phase and astaxanthin accumulation in red the phase. The results showed that dual-substrates mixotrophy significantly increased the biomass productivity during green growth phase up to 2-fold compared to phototrophic controls. Furthermore, supplementation of dual-substrate to the red phase increased astaxanthin accumulation by 10% in the dual-substrate group compared to single-substrate acetate and no substrate. This dual-substrate mixotrophy approach shows promise for cultivating Haematococcus for commercial production of biological astaxanthin in indoor closed systems.
关键词	acetate astaxanthin dual-substrate mixotrophic cultivation pyruvate
DOI	10.1002/biot.202300095
收录类别	SCI
语种	英语
资助项目	Science and Technology Innovation Base and Talent Program in Sichuan Province, China[2022JDGD0026]; Key Research and Development Program of Jiangsu Province, China[BE2021691]
WOS研究方向	Biochemistry & Molecular Biology ; Biotechnology & Applied Microbiology
WOS类目	Biochemical Research Methods ; Biotechnology & Applied Microbiology
WOS记录号	WOS:001015858800001
出版者	WILEY-V C H VERLAG GMBH
WOS关键词	LIGHT-INTENSITY ; GREEN-ALGA ; PLUVIALIS ; ACETATE ; GROWTH ; ACCUMULATION ; CARBON ; CULTIVATION ; CULTURES ; GLUCOSE
引用统计	被引频次：5[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.qdio.ac.cn/handle/337002/182383
专题	实验海洋生物学重点实验室
通讯作者	Li, Jian
作者单位	1.Panzhihua Univ, Coll Biol & Chem Engn, Coll Agr Sci, Panzhihua, Peoples R China 2.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao, Peoples R China 3.Cairo Univ, Dept Agr Engn, Giza, Egypt 4.Jiangsu Univ, Biofuels Inst, Sch Emergency Management, Sch Environm & Safety Engn, Zhenjiang, Peoples R China
推荐引用方式 GB/T 7714	Khazi, Mahammed Ilyas,Liaqat, Fakhra,Gu, Wenhui,et al. Astaxanthin production from the microalga Haematococcus lacustris with a dual substrate mixotrophy strategy[J]. BIOTECHNOLOGY JOURNAL,2023:11.
APA	Khazi, Mahammed Ilyas,Liaqat, Fakhra,Gu, Wenhui,Mohamed, Badr,Zhu, Daochen,&Li, Jian.(2023).Astaxanthin production from the microalga Haematococcus lacustris with a dual substrate mixotrophy strategy.BIOTECHNOLOGY JOURNAL,11.
MLA	Khazi, Mahammed Ilyas,et al."Astaxanthin production from the microalga Haematococcus lacustris with a dual substrate mixotrophy strategy".BIOTECHNOLOGY JOURNAL (2023):11.