Heat stress and evisceration caused lipid metabolism and neural transduction changes in sea cucumber: Evidence from metabolomics

doi:10.1016/j.marpolbul.2022.113993

	Heat stress and evisceration caused lipid metabolism and neural transduction changes in sea cucumber: Evidence from metabolomics
	Huo, Da ; Su, Fang; Cui, Wei; Liu, Shilin ; Zhang, Libin ; Yang, Hongsheng; Sun, Lina 1
	2022-09-01
发表期刊	MARINE POLLUTION BULLETIN
ISSN	0025-326X
卷号	182 页码:10
通讯作者	Sun, Lina([email protected])
摘要	When encountering adverse environmental conditions, some holothurians can eject their internal organs in a process called evisceration. As global warming intensified, eviscerated and intact sea cucumbers both experience heat stress, but how they performed was uncertain. We constructed 24 metabolomics profiles to reveal the metabolite changes of eviscerated and intact sea cucumbers under normal and high temperature conditions, respectively. Carboxylic acids and fatty acyls were the most abundant metabolic categories in evisceration and heat stress treatments, respectively. Neural transduction was involved in sea cucumber evisceration and stress response, and the commonly enriched pathway was ???neuroactive ligand-receptor interaction???. Lipid metabolism in eviscerated sea cucumbers differed from those of intact individuals and was more seriously affected by heat stress. Choline is a key metabolite for revealing the evisceration mechanism. Our results contribute to under-standing the mechanisms of evisceration in sea cucumbers, and how sea cucumbers might respond to increas-ingly warming ocean conditions.
关键词	< italic > Apostichopus japonicus < italic > Evisceration Autotomy Environmental stress Metabolome Thermal stress
DOI	10.1016/j.marpolbul.2022.113993
收录类别	SCI
语种	英语
WOS研究方向	Environmental Sciences & Ecology ; Marine & Freshwater Biology
WOS类目	Environmental Sciences ; Marine & Freshwater Biology
WOS记录号	WOS:000874842200005
出版者	PERGAMON-ELSEVIER SCIENCE LTD
引用统计	被引频次：6[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.qdio.ac.cn/handle/337002/180516
专题	海洋生态与环境科学重点实验室
通讯作者	Sun, Lina
作者单位	1.Chinese Acad Sci, Inst Oceanol, CAS Key Lab Marine Ecol & Environm Sci, Qingdao 266071, Peoples R China 2.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Ecol & Environm Sci, Qingdao 266237, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 4.Shandong Prov Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China
通讯作者单位	海洋生态与环境科学重点实验室
推荐引用方式 GB/T 7714	Huo, Da,Su, Fang,Cui, Wei,et al. Heat stress and evisceration caused lipid metabolism and neural transduction changes in sea cucumber: Evidence from metabolomics[J]. MARINE POLLUTION BULLETIN,2022,182:10.
APA	Huo, Da.,Su, Fang.,Cui, Wei.,Liu, Shilin.,Zhang, Libin.,...&Sun, Lina.(2022).Heat stress and evisceration caused lipid metabolism and neural transduction changes in sea cucumber: Evidence from metabolomics.MARINE POLLUTION BULLETIN,182,10.
MLA	Huo, Da,et al."Heat stress and evisceration caused lipid metabolism and neural transduction changes in sea cucumber: Evidence from metabolomics".MARINE POLLUTION BULLETIN 182(2022):10.