Institutional Repository of Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences
| Genome-wide association study for desirable traits in the Pacific oyster Crassostrea gigas (Thunberg) | |
| Liu, Sheng1,2,3,4; Li, Li1,2,5,6,7; Shi, Ruihui1,2,3,5,6; Wang, Wei1,2,3,7; Wu, Fucun1,2,3,7,8; Zhang, Guofan1,2,3,6,7 | |
| 2022-06-07 | |
| 发表期刊 | AQUACULTURE RESEARCH
 |
| ISSN | 1355-557X |
| 页码 | 9 |
| 通讯作者 | Li, Li([email protected]) ; Zhang, Guofan([email protected]) |
| 摘要 | The Pacific oyster, Crassostrea gigas (Thunberg), from the northwest Pacific Ocean has been introduced for aquaculture in many areas. Despite its economic importance, genetic dissection for growth, shell shape and yield traits have not been reported thoroughly. To explore single nucleotide polymorphisms (SNPs) associated with desired traits in Pacific oyster, a genome-wide association study (GWAS) was conducted based on the 190 K high-density SNP array. Growth, shell shape and yield traits, including shell height, condition index and dressing percentage, were studied. Moderate to high phenotypic correlations between shell height and other growth-related traits in the studied wild population were observed (r = 0.38-0.77, p < 0.05), and the dressing percentage was correlated with the condition index (r = 0.6, p < 0.05). The condition index had a moderate positive correlation with glycogen and fat content (r = 0.22-0.35, p < 0.05). The results of GWAS indicated that 11 SNPs were significantly associated with the studied traits. Shell height, body weight and soft body weight were all associated with a significant nonsynonymous SNP (scaffold731_92759), phenotypic variation explanations associated with this single SNP are 8.59%, 8.12% and 8.13%, respectively. This SNP is located in the protein-coding region of the serine protease inhibitor dipetalogastin, which is thought to be involved in food digestion and absorption. This polymorphism may affect the ability of dipetalogastin to inhibit serine proteases, thereby affecting the oyster's growth. This study identified new candidate genes and SNPs related to oyster growth, which is useful for marker-assisted selection. |
| 关键词 | candidate gene genome-wide association study growth-related traits Pacific oyster |
| DOI | 10.1111/are.15903 |
| 收录类别 | SCI |
| 语种 | 英语 |
| 资助项目 | Major Scientific and Technological Innovation Project of Shandong Province[2021LZGC029]; Major Scientific and Technological Innovation Project of Shandong Province[2019JZZY010813]; Strategic Priority Research Program of the Chinese Academy of Sciences[XDA24030105]; National Natural Science Foundation of China[31572620]; National Natural Science Foundation of China[31530079]; China Agriculture Research System of MOF; Fundamental Research Foundation for Provincial University in Zhejiang Province |
| WOS研究方向 | Fisheries |
| WOS类目 | Fisheries |
| WOS记录号 | WOS:000807077500001 |
| 出版者 | WILEY |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.qdio.ac.cn/handle/337002/179450 |
| 专题 | 实验海洋生物学重点实验室 |
| 通讯作者 | Li, Li; Zhang, Guofan |
| 作者单位 | 1.Chinese Acad Sci, Qingdao, Peoples R China 2.Chinese Acad Sci, Inst Oceanol, Ctr Ocean Megasci, Shandong Prov Key Lab Expt Marine Biol, Qingdao, Peoples R China 3.Pilot Natl Lab Marine Sci & Technol, Lab Marine Biol & Biotechnol, Qingdao, Peoples R China 4.Zhejiang Wanli Univ, Inst Mariculture Breeding & Seed Ind, Ningbo, Peoples R China 5.Pilot Natl Lab Marine Sci & Technol, Lab Marine Fisheries Sci & Food Prod Proc, Qingdao, Peoples R China 6.Univ Chinese Acad Sci, Beijing, Peoples R China 7.Natl & Local Joint Engn Lab Ecol Mariculture, Qingdao, Peoples R China 8.Chinese Acad Sci, Innovat Seed Design, Wuhan, Peoples R China |
| 第一作者单位 | 中国科学院海洋大科学研究中心 |
| 通讯作者单位 | 中国科学院海洋大科学研究中心 |
| 推荐引用方式 GB/T 7714 | Liu, Sheng,Li, Li,Shi, Ruihui,et al. Genome-wide association study for desirable traits in the Pacific oyster Crassostrea gigas (Thunberg)[J]. AQUACULTURE RESEARCH,2022:9. |
| APA | Liu, Sheng,Li, Li,Shi, Ruihui,Wang, Wei,Wu, Fucun,&Zhang, Guofan.(2022).Genome-wide association study for desirable traits in the Pacific oyster Crassostrea gigas (Thunberg).AQUACULTURE RESEARCH,9. |
| MLA | Liu, Sheng,et al."Genome-wide association study for desirable traits in the Pacific oyster Crassostrea gigas (Thunberg)".AQUACULTURE RESEARCH (2022):9. |
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| Aquaculture Research（994KB） | 期刊论文 | 出版稿 | 限制开放 | CC BY-NC-SA | 浏览 | |
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