Institutional Repository of Key Laboratory of Marine Ecology & Environmental Sciences, CAS
| Microplastic-induced apoptosis and metabolism responses in marine Dinoflagellate, Karenia mikimotoi | |
| Zhao, Ting1,2; Tan, Liju1; Han, Xiaotian3; Wang, Xutao2; Zhang, Yafeng2; Ma, Xiaofeng4; Lin, Kun1; Wang, Rui1; Ni, Ziqi1; Wang, Jiayin1; Wang, Jiangtao1 | |
| 2022-01-15 | |
| 发表期刊 | SCIENCE OF THE TOTAL ENVIRONMENT
 |
| ISSN | 0048-9697 |
| 卷号 | 804页码:10 |
| 通讯作者 | Wang, Jiangtao([email protected]) |
| 摘要 | Microplastics (MPs) occur widely in marine environments, and disturb the balance of aquatic ecosystems. In this study, programmed cell apoptosis in marine dinoflagellate, Karenia mikimotoi exposed to 10 mg L-1 micro/nanoplastics (MPs/NPs; polystyrene and polymethyl methacrylate) for 72 h was assessed. Prior to the toxicity assay, MPs/NPs were dialyzed to remove possible additives. Cell viability, membrane integrity, cell apoptosis, and total DNA concentration were measured to assess programmed cell apoptosis in K. mikimotoi following ex-posure to MPs/NPs. A transcriptome analysis was used to explore the potential toxic mechanism of MPs to K. mikimotoi. Programmed cell apoptosis was related to the size of MPs/NPs, and NPs could more easily impair cell viability, and reduced cell membrane integrity and DNA concentration. NP particles caused continuous apoptosis of K. mikimotoi compared to MP particles. Size had the greatest effect on toxicity in K. mikimotoi. In conclu-sion, the results evidenced that both MPs and NPs have a negative impact on the marine dinoflagellate, K. mikimotoi. However, NPs were more harmful to K mikimotoi than MPs, highlighting the potential ecological problems associated with exposure to NPs. (C) 2021 Elsevier B.V. All rights reserved. |
| 关键词 | Micro/nano-scaled plastics Cell viability Membrane integrity Cell apoptosis DNA concentration Transcriptome analysis |
| DOI | 10.1016/j.scitotenv.2021.150252 |
| 收录类别 | SCI |
| 语种 | 英语 |
| 资助项目 | National Key Research and Development Programof China[2019YFC1407802]; National Natural Science Foundation of China[41876078]; Natural Science Foundation of Shandong[ZR2018MD016]; Foundation of Key Laboratory of Integrated Marine Monitoring and Applied Technologies for Harmful Algal Blooms[MATHAB201707] |
| WOS研究方向 | Environmental Sciences & Ecology |
| WOS类目 | Environmental Sciences |
| WOS记录号 | WOS:000704389800003 |
| 出版者 | ELSEVIER |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.qdio.ac.cn/handle/337002/176649 |
| 专题 | 海洋生态与环境科学重点实验室 |
| 通讯作者 | Wang, Jiangtao |
| 作者单位 | 1.Ocean Univ China, Key Lab Marine Chem Theory & Technol, Minist Educ, Qingdao 266100, Peoples R China 2.Minist Ecol & Environm, Ecoenvironm Monitoring & Res Ctr, Pearl River Valley & South China Sea Ecol & Envir, Guangzhou 510610, Peoples R China 3.Chinese Acad Sci, Inst Oceanol, Changjiang River Estuary Ecosyst Res Stn, Qingdao 266071, Peoples R China 4.SCIEX China, Shanghai 200233, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhao, Ting,Tan, Liju,Han, Xiaotian,et al. Microplastic-induced apoptosis and metabolism responses in marine Dinoflagellate, Karenia mikimotoi[J]. SCIENCE OF THE TOTAL ENVIRONMENT,2022,804:10. |
| APA | Zhao, Ting.,Tan, Liju.,Han, Xiaotian.,Wang, Xutao.,Zhang, Yafeng.,...&Wang, Jiangtao.(2022).Microplastic-induced apoptosis and metabolism responses in marine Dinoflagellate, Karenia mikimotoi.SCIENCE OF THE TOTAL ENVIRONMENT,804,10. |
| MLA | Zhao, Ting,et al."Microplastic-induced apoptosis and metabolism responses in marine Dinoflagellate, Karenia mikimotoi".SCIENCE OF THE TOTAL ENVIRONMENT 804(2022):10. |
| 条目包含的文件 | ||||||
| 文件名称/大小 | 文献类型 | 版本类型 | 开放类型 | 使用许可 | ||
| 1-s2.0-S004896972105（2580KB） | 期刊论文 | 出版稿 | 限制开放 | CC BY-NC-SA | 浏览 | |
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