Characterization of Different Salt Forms of Chitooligosaccharides and Their Effects on Nitric Oxide Secretion by Macrophages

doi:10.3390/molecules26092563

IOCAS-IR > 实验海洋生物学重点实验室

	Characterization of Different Salt Forms of Chitooligosaccharides and Their Effects on Nitric Oxide Secretion by Macrophages
	Xing, Ronge1,2,3 ; Xu, Chaojie1,2,3,4 ; Gao, Kun1,2,3,4 ; Yang, Haoyue1,2,3 ; Liu, Yongliang3 ; Fan, Zhaoqian 1,2,3; Liu, Song 1,2,3; Qin, Yukun1,2,3 ; Yu, Huahua1,2,3 ; Li, Pengcheng1,2,3
	2021-05-01
发表期刊	MOLECULES
卷号	26 期号:9 页码:17
通讯作者	Xing, Ronge([email protected])
摘要	In this paper, chitooligosaccharides in different salt forms, such as chitooligosaccharide lactate, citrate, adipate, etc., were prepared by the microwave method. They were characterized by SEM, FTIR, NMR, etc., and the nitric oxide (NO) expression was determined in RAW 264.7 cells. The results showed that pure chitooligosaccharide was an irregular spherical shape with rough surface, and its different salt type products are amorphous solid with different honeycomb sizes. In addition to the characteristic absorption peaks of chitooligosaccharides, in FTIR, the characteristic absorption of carboxyl group, methylene group, and aromatic group in corresponding acid appeared. The characteristic absorption peaks of carbon in carboxyl group, hydrogen and carbon in methyl, methylene group, and aromatic group in corresponding acid also appeared in NMR. Therefore, the sugar ring structure and linking mode of chitooligosaccharides did not change after salt formation of chitooligosaccharides. Different salt chitooligosaccharides are completely different in promoting NO secretion by macrophages, and pure chitooligosaccharides are the best.
关键词	pure chitooligosaccharides chitooligosaccharides salts characterization promoting NO production
DOI	10.3390/molecules26092563
收录类别	SCI
语种	英语
资助项目	Key deployment projects of the Marine Science Research Center of Chinese Academy of Sciences[COMS2020J04]; Key Research and Development Program of Shandong Province[2019YYSP028]
WOS研究方向	Biochemistry & Molecular Biology ; Chemistry
WOS类目	Biochemistry & Molecular Biology ; Chemistry, Multidisciplinary
WOS记录号	WOS:000650682300001
出版者	MDPI
引用统计	被引频次：5[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.qdio.ac.cn/handle/337002/170884
专题	实验海洋生物学重点实验室
通讯作者	Xing, Ronge
作者单位	1.Chinese Acad Sci, Inst Oceanol, Ctr Ocean Mega Sci, CAS, 7 Nanhai Rd, Qingdao 266071, Peoples R China 2.Chinese Acad Sci, Inst Oceanol, Ctr Ocean Mega Sci, Shandong Prov Key Lab Expt Marine Biol, 7 Nanhai Rd, Qingdao 266071, Peoples R China 3.Pilot Natl Lab Marine Sci & Technol Qingdao, Lab Marine Drugs & Bioprod, 1 Wenhai Rd, Qingdao 266237, Peoples R China 4.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
第一作者单位	中国科学院海洋研究所
通讯作者单位	中国科学院海洋研究所
推荐引用方式 GB/T 7714	Xing, Ronge,Xu, Chaojie,Gao, Kun,et al. Characterization of Different Salt Forms of Chitooligosaccharides and Their Effects on Nitric Oxide Secretion by Macrophages[J]. MOLECULES,2021,26(9):17.
APA	Xing, Ronge.,Xu, Chaojie.,Gao, Kun.,Yang, Haoyue.,Liu, Yongliang.,...&Li, Pengcheng.(2021).Characterization of Different Salt Forms of Chitooligosaccharides and Their Effects on Nitric Oxide Secretion by Macrophages.MOLECULES,26(9),17.
MLA	Xing, Ronge,et al."Characterization of Different Salt Forms of Chitooligosaccharides and Their Effects on Nitric Oxide Secretion by Macrophages".MOLECULES 26.9(2021):17.

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