The secondary bacterial infection caused by WSSV outbreaks impacts shrimp Marsupenaeus japonicus' growth as well as its intestinal microbiota's composition and function

doi:10.46989/001c.21687

IOCAS-IR

	The secondary bacterial infection caused by WSSV outbreaks impacts shrimp Marsupenaeus japonicus' growth as well as its intestinal microbiota's composition and function
	He, Zihao 1; Zhao, Jichen 1; Liao, Xuzheng 2; Chen, Xieyan 1; Fu, Zhibin 1; Sun, Chengbo 1,3,4; Ni, Zuotao 5
	2020
发表期刊	ISRAELI JOURNAL OF AQUACULTURE-BAMIDGEH
ISSN	0792-156X
卷号	72 页码:17
通讯作者	Sun, Chengbo([email protected]) ; Ni, Zuotao([email protected])
摘要	Intestinal microbiota homeostasis is a complex ecosystem and is essential for promoting aquatic animals' growth. Invading pathogens can cause dynamical composition and structure change in the hosts' microbiota due to this affecting their functions. WSSV is one of the most common and dangerous shrimp pathogens, which leads to white spot disease with too high mortality. A few studies on shrimp intestinal microbiota mainly focused on the changes during acute infection stage. Marsupenaeus japonicus is one of the most cultured shrimp with a decent ability to cope with environmental changes. In the current research, using M. japonicus as a model, we compared the differences of intestinal microbiota between healthy shrimp and the shrimp that survived through the WSSV outbreak. Our study showed that compared to the healthy M. japonicus, the WSSV outbreak disrupted intestinal microbiota structure in the survived shrimp: There was less potential beneficial bacteria and more harmful bacteria. Furthermore, the diversity and total abundance of intestinal microbiota in WSSV-survived shrimp increased significantly. On top of that, a metagenomic analysis by PICRUSt suggested that the changed intestinal microbiota could help the host to combat the secondary bacterial infections caused by WSSV outbreaks by regulating cell growth and death, reducing cell motility, improving energy metabolism, and increasing intestinal enzyme activities regardless the smaller sizes of WSSV-survived shrimp. This could be a result of excessive energy consumption and reduced nutrient-absorbing intestinal microbiota. Our study indicated that shrimp intestinal microbiota plays a fundamental role in combating against secondary infections and regulating the hosts' growth post WSSV outbreaks. The eventual goal is to development of more efficient diagnostics and therapeutic strategies.
关键词	Marsupenaeus japonicus WSSV intestinal microbiota growth performance secondary bacterial infections immunity strategy
DOI	10.46989/001c.21687
收录类别	SCI
语种	英语
资助项目	key research and development projects in Guangdong Province[2020B0202010009]; key research and development projects in Guangdong Province[2319412525]; Fangchenggang Science and Technology Plan Project[AD19008017]
WOS研究方向	Fisheries
WOS类目	Fisheries
WOS记录号	WOS:000648877900001
出版者	ISRAELI JOURNAL OF AQUACULTURE-BAMIDGEH
引用统计	被引频次：5[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.qdio.ac.cn/handle/337002/170872
专题	中国科学院海洋研究所
通讯作者	Sun, Chengbo; Ni, Zuotao
作者单位	1.Guangdong Ocean Univ, Coll Fisheries, Zhanjiang, Peoples R China 2.Sun Yat Sen Univ, Southern Marine Sci & Engn Guangdong Lab Zhuhai, Sch Marine Sci, Guangzhou, Peoples R China 3.Guangdong Prov Lab Southern Marine Sci & Engn, Zhanjiang, Peoples R China 4.Guangdong Prov Key Lab Pathogen Biol & Epidemiol, Zhanjiang, Peoples R China 5.Chinese Acad Sci, Inst Oceanol, Qingdao, Peoples R China
通讯作者单位	中国科学院海洋研究所
推荐引用方式 GB/T 7714	He, Zihao,Zhao, Jichen,Liao, Xuzheng,et al. The secondary bacterial infection caused by WSSV outbreaks impacts shrimp Marsupenaeus japonicus' growth as well as its intestinal microbiota's composition and function[J]. ISRAELI JOURNAL OF AQUACULTURE-BAMIDGEH,2020,72:17.
APA	He, Zihao.,Zhao, Jichen.,Liao, Xuzheng.,Chen, Xieyan.,Fu, Zhibin.,...&Ni, Zuotao.(2020).The secondary bacterial infection caused by WSSV outbreaks impacts shrimp Marsupenaeus japonicus' growth as well as its intestinal microbiota's composition and function.ISRAELI JOURNAL OF AQUACULTURE-BAMIDGEH,72,17.
MLA	He, Zihao,et al."The secondary bacterial infection caused by WSSV outbreaks impacts shrimp Marsupenaeus japonicus' growth as well as its intestinal microbiota's composition and function".ISRAELI JOURNAL OF AQUACULTURE-BAMIDGEH 72(2020):17.