Identification of Growth-Associated Genes by Genome-Wide Association Study and Their Potential Application in the Breeding of Pacific White Shrimp (Litopenaeus vannamei)

doi:10.3389/fgene.2021.611570

IOCAS-IR > 实验海洋生物学重点实验室

	Identification of Growth-Associated Genes by Genome-Wide Association Study and Their Potential Application in the Breeding of Pacific White Shrimp (Litopenaeus vannamei)
	Lyu, Ding 1,2,3; Yu, Yang1,2,3 ; Wang, Quanchao1,3,4 ; Luo, Zheng1,3,5 ; Zhang, Qian1,3,5 ; Zhang, Xiaojun 1,2,3; Xiang, Jianhai1,3 ; Li, Fuhua 1,2,3,6
	2021-04-07
发表期刊	FRONTIERS IN GENETICS
卷号	12 页码:9
通讯作者	Li, Fuhua([email protected])
摘要	The Pacific white shrimp (Litopenaeus vannamei) is the most widely cultured shrimp in the world. A great attention has been paid to improve its body weight (BW) at harvest through genetic selection for decades. Genome-wide association study (GWAS) is a tool to dissect the genetic basis of the traits. In this study, a GWAS approach was conducted to find genes related to BW through genotyping 94,113 single nucleotide polymorphisms (SNPs) in 200 individuals from a breeding population. Four BW-related SNPs located in LG19 and LG39 were identified. Through further candidate gene association analysis, the SNPs in two candidate genes, deoxycytidylate deaminase and non-receptor protein tyrosine kinase, were found to be related with the body weight of the shrimp. Marker-assisted best linear unbiased prediction (MA-BLUP) based on the SNPs in these two genes was used to estimate the breeding values, and the result showed that the highest prediction accuracy of MA-BLUP was increased by 9.4% than traditional BLUP. These results will provide useful information for the marker-assisted breeding in L. vannamei.
关键词	GWAS growth trait marker assisted BLUP genetic breeding Litopenaeus vannamei
DOI	10.3389/fgene.2021.611570
收录类别	SCI
语种	英语
资助项目	Strategic Priority Research Program of the Chinese Academy of Sciences[XDA24030105]; National Key R&D Program of China[2018YFD0901301]; Agricultural Variety Improvement Project of Shandong Province[2019LZGC014]; China Agriculture Research System-48[CARS-48]
WOS研究方向	Genetics & Heredity
WOS类目	Genetics & Heredity
WOS记录号	WOS:000641715100001
出版者	FRONTIERS MEDIA SA
引用统计	被引频次：23[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.qdio.ac.cn/handle/337002/170631
专题	实验海洋生物学重点实验室
通讯作者	Li, Fuhua
作者单位	1.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao, Peoples R China 2.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Biol & Biotechnol, Qingdao, Peoples R China 3.Chinese Acad Sci, Ctr Ocean Mega Sci, Qingdao, Peoples R China 4.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai, Peoples R China 5.Univ Chinese Acad Sci, Beijing, Peoples R China 6.Chinese Acad Sci, Innovat Seed Design, Wuhan, Peoples R China
第一作者单位	中国科学院海洋研究所
通讯作者单位	中国科学院海洋研究所
推荐引用方式 GB/T 7714	Lyu, Ding,Yu, Yang,Wang, Quanchao,et al. Identification of Growth-Associated Genes by Genome-Wide Association Study and Their Potential Application in the Breeding of Pacific White Shrimp (Litopenaeus vannamei)[J]. FRONTIERS IN GENETICS,2021,12:9.
APA	Lyu, Ding.,Yu, Yang.,Wang, Quanchao.,Luo, Zheng.,Zhang, Qian.,...&Li, Fuhua.(2021).Identification of Growth-Associated Genes by Genome-Wide Association Study and Their Potential Application in the Breeding of Pacific White Shrimp (Litopenaeus vannamei).FRONTIERS IN GENETICS,12,9.
MLA	Lyu, Ding,et al."Identification of Growth-Associated Genes by Genome-Wide Association Study and Their Potential Application in the Breeding of Pacific White Shrimp (Litopenaeus vannamei)".FRONTIERS IN GENETICS 12(2021):9.

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