Highlights of animal venom research on the geographical variations of toxin components, toxicities and envenomation therapy

doi:10.1016/j.ijbiomac.2020.10.190

IOCAS-IR > 实验海洋生物学重点实验室

	Highlights of animal venom research on the geographical variations of toxin components, toxicities and envenomation therapy
	Yu, Chunlin1,3 ; Yu, Huahua1,2 ; Li, Pengcheng1,2
	2020-12-15
发表期刊	INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
ISSN	0141-8130
卷号	165 页码:2994-3006
通讯作者	Yu, Huahua([email protected])
摘要	Geographical variation of animal venom is common among venomous animals. This kind of intraspecific variation based on geographical location mainly concerned from envenomation cases and brought new problems in animal venom studies, including venom components regulatory mechanisms, differentiation of venom activities, and clinical treatment methods. At present, food is considered as the most related factor influencing venom development. Related research defined the variational venomous animal species by the comparison of venom components and activities in snakes, jellyfish, scorpions, cone snails, ants, parasitoid wasps, spiders and toads. In snake venom studies, researchers found that antivenom effectiveness was variated to different located venom samples. As described in some snake venom research, developing region-specific antivenom is the development trend. The difficulties of developing region-specific antivenom and theoretical solutions have been discussed. This review summarized biological studies of animal venom geographical variation by species, compared venom components and major biological activities of the vary venom from the same species, and listed the basic methods in comparing venom protein compositions and major toxicity differences to provide a comprehensive reference. (c) 2020 Elsevier B.V. All rights reserved.
关键词	Snake venom Jellyfish venom Scorpion venom Venom variation Geographical variation
DOI	10.1016/j.ijbiomac.2020.10.190
收录类别	SCI
语种	英语
资助项目	National Natural Science Foundation of China[41776163]; National Natural Science Foundation of China[41876164]; National Key R&D Program of China[2019YFC0312605]; National Key R&D Program of China[2017YFE0111100-04]; Shandong Province Natural Science Foundation of China[ZR2019QD012]; Qingdao Science and Technology Project[17-3-3-21-nsh]
WOS研究方向	Biochemistry & Molecular Biology ; Chemistry ; Polymer Science
WOS类目	Biochemistry & Molecular Biology ; Chemistry, Applied ; Polymer Science
WOS记录号	WOS:000600773500129
出版者	ELSEVIER
引用统计	被引频次：19[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.qdio.ac.cn/handle/337002/169903
专题	实验海洋生物学重点实验室
通讯作者	Yu, Huahua
作者单位	1.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Ctr Ocean Megasci, 7 Nanhai Rd, Qingdao 266071, Peoples R China 2.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Drugs & Bioprod, 1 Wenhai Rd, Qingdao 266237, Peoples R China 3.Univ Chinese Acad Sci, Coll Earth & Planetary Sci, Beijing 100049, Peoples R China
第一作者单位	中国科学院海洋大科学研究中心
通讯作者单位	中国科学院海洋大科学研究中心
推荐引用方式 GB/T 7714	Yu, Chunlin,Yu, Huahua,Li, Pengcheng. Highlights of animal venom research on the geographical variations of toxin components, toxicities and envenomation therapy[J]. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,2020,165:2994-3006.
APA	Yu, Chunlin,Yu, Huahua,&Li, Pengcheng.(2020).Highlights of animal venom research on the geographical variations of toxin components, toxicities and envenomation therapy.INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,165,2994-3006.
MLA	Yu, Chunlin,et al."Highlights of animal venom research on the geographical variations of toxin components, toxicities and envenomation therapy".INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES 165(2020):2994-3006.

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