The Polymorphism ofLvMMD2and Its Association with Growth Traits inLitopenaeus vannamei

doi:10.1007/s10126-020-09977-0

IOCAS-IR > 实验海洋生物学重点实验室

	The Polymorphism ofLvMMD2and Its Association with Growth Traits inLitopenaeus vannamei
	Wang, Quanchao1,2,3 ; Yu, Yang1,3,4 ; Zhang, Qian1,4,5 ; Luo, Zheng1,4,5 ; Zhang, Xiaojun 1,3,4; Xiang, Jianhai1,4 ; Li, Fuhua 1,3,4,6
	2020-08-01
发表期刊	MARINE BIOTECHNOLOGY
ISSN	1436-2228
卷号	22 期号:4 页码:564-571
摘要	The Pacific white shrimpLitopenaeus vannameiis one of the major economic aquaculture species. The growth trait is considered as the most important trait inL. vannameiaquaculture. Identification of the genetic components underlying growth-related traits inL. vannameicould be useful for the selective breeding of growth trait. Our previous work identified several growth-related SNPs by genome-wide association study (GWAS). Based on the assembled genome, we identified a new candidate gene (LvMMD2) beside the associated marker. This gene encodes the progestin and AdipoQ receptor 10 (PAQR10) protein. We further investigate the polymorphisms ofLvMMD2and their association with body weight ofL. vannamei. By resequencing the coding region ofLvMMD2, a total of 8 SNPs were identified, including 6 synonymous mutations and 2 nonsynonymous mutations. Association analyses based on a population of 322 individuals revealed that several SNPs located in the coding region ofLvMMD2were significantly associated with the body weight, especially the nonsynonymous mutation named as MMD_5 contributed the most association to the trait and it could explain 10.5% of phenotypic variance. In addition, several genes involved in growth and development have been identified asLvMMD2-interacting genes. These findings strongly suggested thatLvMMD2might be an important gene regulating the shrimp growth. More importantly, the MMD_5 could be a promising candidate locus for marker-assisted selection (MAS) of the body weight inL. vannamei.
关键词	Penaeid shrimp Growth traits GWAS Candidate gene MMD2
DOI	10.1007/s10126-020-09977-0
收录类别	SCI
语种	英语
资助项目	National Key R&D Program of China[2018 YFD0901301]; National Key R&D Program of China[2018YFD0900303]; Strategic Priority Research Program of the Chinese Academy of Sciences[XDA24030105]; Agricultural Variety Improvement Project of Shandong Province[2019LZGC014]; China Agriculture Research System-48
WOS研究方向	Biotechnology & Applied Microbiology ; Marine & Freshwater Biology
WOS类目	Biotechnology & Applied Microbiology ; Marine & Freshwater Biology
WOS记录号	WOS:000542504500001
出版者	SPRINGER
引用统计	被引频次：13[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
版本	出版稿
条目标识符	http://ir.qdio.ac.cn/handle/337002/167796
专题	实验海洋生物学重点实验室
通讯作者	Li, Fuhua
作者单位	1.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China 2.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China 3.Chinese Acad Sci, Ctr Ocean Megasci, Qingdao 266071, Peoples R China 4.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Biol & Biotechnol, Qingdao 266237, Peoples R China 5.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 6.Chinese Acad Sci, Innovat Seed Design, Wuhan, Peoples R China
第一作者单位	实验海洋生物学重点实验室; 中国科学院海洋大科学研究中心
通讯作者单位	实验海洋生物学重点实验室; 中国科学院海洋大科学研究中心
推荐引用方式 GB/T 7714	Wang, Quanchao,Yu, Yang,Zhang, Qian,et al. The Polymorphism ofLvMMD2and Its Association with Growth Traits inLitopenaeus vannamei[J]. MARINE BIOTECHNOLOGY,2020,22(4):564-571.
APA	Wang, Quanchao.,Yu, Yang.,Zhang, Qian.,Luo, Zheng.,Zhang, Xiaojun.,...&Li, Fuhua.(2020).The Polymorphism ofLvMMD2and Its Association with Growth Traits inLitopenaeus vannamei.MARINE BIOTECHNOLOGY,22(4),564-571.
MLA	Wang, Quanchao,et al."The Polymorphism ofLvMMD2and Its Association with Growth Traits inLitopenaeus vannamei".MARINE BIOTECHNOLOGY 22.4(2020):564-571.

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