| The antioxidant activities and neuroprotective effect of polysaccharides from the starfish Asterias rollestoni | |
Zhang, Wenjing1,2,3 ; Wang, Jing1,3; Jin, Weihua1,2; Zhang, Quanbin1; Zhang, QB
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| 2013-05-05 | |
| 发表期刊 | CARBOHYDRATE POLYMERS
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| ISSN | 0144-8617 |
| 卷号 | 95期号:1页码:9-15 |
| 文章类型 | Article |
| 摘要 | After the starfish was defatted with isopropyl alcohol and ethanol, crude polysaccharide was extracted by 0.15 mol/L NCl. Anion exchange chromatography was performed to fractionate the sample into two fractions, SF-1 and SF-2. Chemical analysis showed that the major component of SF-1 was a glucan consisting of a backbone of 1 -> 3 linked beta-D-glucopyranose residues, and it had a minor glucan component containing a backbone of 1 -> 3 linked alpha-D-glucopyranose residues. SF-2 was a mannoglucan sulfate. SF-2 displayed the highest antioxidant activity among the polysaccharides. Moreover, SF-1 and SF-2 exhibited neuroprotective activities in a neurotoxicity model of Parkinson's disease (PD). (C) 2013 Elsevier Ltd. All rights reserved.; After the starfish was defatted with isopropyl alcohol and ethanol, crude polysaccharide was extracted by 0.15 mol/L NCl. Anion exchange chromatography was performed to fractionate the sample into two fractions, SF-1 and SF-2. Chemical analysis showed that the major component of SF-1 was a glucan consisting of a backbone of 1 -> 3 linked beta-D-glucopyranose residues, and it had a minor glucan component containing a backbone of 1 -> 3 linked alpha-D-glucopyranose residues. SF-2 was a mannoglucan sulfate. SF-2 displayed the highest antioxidant activity among the polysaccharides. Moreover, SF-1 and SF-2 exhibited neuroprotective activities in a neurotoxicity model of Parkinson's disease (PD). (C) 2013 Elsevier Ltd. All rights reserved. |
| 关键词 | Starfish Polysaccharide Antioxidant Activity Neuroprotective Activity |
| 学科领域 | Chemistry ; Polymer Science |
| DOI | 10.1016/j.carbpol.2013.02.035 |
| URL | 查看原文 |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS研究方向 | Chemistry ; Polymer Science |
| WOS类目 | Chemistry, Applied ; Chemistry, Organic ; Polymer Science |
| WOS记录号 | WOS:000319029700002 |
| WOS关键词 | POLYHYDROXYLATED STEROIDS ; SULFATED POLYSACCHARIDES ; MARINE-INVERTEBRATES ; ANTICOAGULANT ; FRACTIONS ; EXTRACTS |
| WOS标题词 | Science & Technology ; Physical Sciences |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.qdio.ac.cn/handle/337002/16725 |
| 专题 | 海洋生物技术研发中心 |
| 通讯作者 | Zhang, QB |
| 作者单位 | 1.Chinese Acad Sci, Inst Oceanol, Qingdao 266071, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.IOCAS Jiangsu, Nantong Marine Sci & Technol R&D Ctr, Nantong 226006, Jiangsu, Peoples R China |
| 第一作者单位 | 中国科学院海洋研究所 |
| 推荐引用方式 GB/T 7714 | Zhang, Wenjing,Wang, Jing,Jin, Weihua,et al. The antioxidant activities and neuroprotective effect of polysaccharides from the starfish Asterias rollestoni[J]. CARBOHYDRATE POLYMERS,2013,95(1):9-15. |
| APA | Zhang, Wenjing,Wang, Jing,Jin, Weihua,Zhang, Quanbin,&Zhang, QB.(2013).The antioxidant activities and neuroprotective effect of polysaccharides from the starfish Asterias rollestoni.CARBOHYDRATE POLYMERS,95(1),9-15. |
| MLA | Zhang, Wenjing,et al."The antioxidant activities and neuroprotective effect of polysaccharides from the starfish Asterias rollestoni".CARBOHYDRATE POLYMERS 95.1(2013):9-15. |
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| The antioxidant acti（903KB） | 限制开放 | CC BY-NC-SA | 浏览 | |||
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