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| Prenylated Phenol and Benzofuran Derivatives from Aspergillus terreus EN-539, an Endophytic Fungus Derived from Marine Red Alga Laurencia okamurai | |
Li, Hong-Lei1,2,3 ; Li, Xiao-Ming1,2,3; Yang, Sui-Qun1,2,3; Meng, Ling-Hong1,2,3; Li, Xin1,2,3; Wang, Bin-Gui1,2,3
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| 2019-11-01 | |
| 发表期刊 | MARINE DRUGS
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| 卷号 | 17期号:11页码:9 |
| 通讯作者 | Wang, Bin-Gui([email protected]) |
| 摘要 | Three new prenylated phenol derivatives, terreprenphenols A-C (1-3), along with four known related compounds (4-7), were isolated from Aspergillus terreus EN-539, an endophytic fungus obtained from the marine red alga Laurencia okamurai. The structures of these compounds were established by extensive analysis of 1D/2D NMR data, mass spectrometric data, and optical rotation (OR). The corresponding relationship between absolute configuration and optical rotation for known compounds anodendroic acid (4) and asperterreusine C (5) was ambiguous in literature, and their absolute configurations were therefore discussed and confirmed for the first time by time-dependent density functional (TDDFT) ECD and OR calculations. Compounds 1-7 inhibited some common aquatic bacteria with MIC values ranging from 2 to 64 mu g/mL. |
| 关键词 | Laurencia okamurai Aspergillus terreus endophytic fungus prenylated phenol benzofuran antibacterial activity |
| DOI | 10.3390/md17110605 |
| 收录类别 | SCI |
| 语种 | 英语 |
| 资助项目 | National Natural Science Foundation of China[31330009]###1177; Natural Science Foundation of Shandong Province[ZR2018BD031]###3097; China Postdoctoral Science Foundation[2018M632732]###3098; National Natural Science Foundation of China[31330009]; Natural Science Foundation of Shandong Province[ZR2018BD031]; China Postdoctoral Science Foundation[2018M632732] |
| WOS研究方向 | Pharmacology & Pharmacy |
| WOS类目 | Chemistry, Medicinal |
| WOS记录号 | WOS:000502262200049 |
| 出版者 | MDPI |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.qdio.ac.cn/handle/337002/164095 |
| 专题 | 实验海洋生物学重点实验室 |
| 通讯作者 | Wang, Bin-Gui |
| 作者单位 | 1.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Nanhai Rd 7, Qingdao 266071, Shandong, Peoples R China 2.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Biol & Biotechnol, Wenhai Rd 1, Qingdao 266237, Shandong, Peoples R China 3.Chinese Acad Sci, Ctr Ocean Megasci, Nanhai Rd 7, Qingdao 266071, Shandong, Peoples R China |
| 第一作者单位 | 中国科学院海洋研究所; 中国科学院海洋大科学研究中心 |
| 通讯作者单位 | 中国科学院海洋研究所; 中国科学院海洋大科学研究中心 |
| 推荐引用方式 GB/T 7714 | Li, Hong-Lei,Li, Xiao-Ming,Yang, Sui-Qun,et al. Prenylated Phenol and Benzofuran Derivatives from Aspergillus terreus EN-539, an Endophytic Fungus Derived from Marine Red Alga Laurencia okamurai[J]. MARINE DRUGS,2019,17(11):9. |
| APA | Li, Hong-Lei,Li, Xiao-Ming,Yang, Sui-Qun,Meng, Ling-Hong,Li, Xin,&Wang, Bin-Gui.(2019).Prenylated Phenol and Benzofuran Derivatives from Aspergillus terreus EN-539, an Endophytic Fungus Derived from Marine Red Alga Laurencia okamurai.MARINE DRUGS,17(11),9. |
| MLA | Li, Hong-Lei,et al."Prenylated Phenol and Benzofuran Derivatives from Aspergillus terreus EN-539, an Endophytic Fungus Derived from Marine Red Alga Laurencia okamurai".MARINE DRUGS 17.11(2019):9. |
| 条目包含的文件 | ||||||
| 文件名称/大小 | 文献类型 | 版本类型 | 开放类型 | 使用许可 | ||
| Prenylated Phenol an（944KB） | 期刊论文 | 出版稿 | 限制开放 | CC BY-NC-SA | 浏览 | |
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