bHLH genes polymorphisms and their association with growth traits in the Pacific oyster Crassostrea gigas

doi:10.1007/s00343-019-9070-4

IOCAS-IR > 实验海洋生物学重点实验室

	bHLH genes polymorphisms and their association with growth traits in the Pacific oyster Crassostrea gigas
	Chen Na 1,2; Li Li 3; Li Chenghua 2; Lin Zhihua 1; Meng Jie3 ; Liu Sheng 3; Song Kai 3; Bao Yongbo 1
	2019-12-05
发表期刊	JOURNAL OF OCEANOLOGY AND LIMNOLOGY
ISSN	2096-5508
页码	7
摘要	The basic helix-loop-helix (bHLH) genes encode a large superfamily of transcription factors in the Pacific oyster (Crassostrea gigas), and play a very important role in regulation of growth and development. To investigate the oyster growth traits and the associations with bHLH genes variations, we analyzed the gene polymorphisms-traits association in a wild population, and confirmed the results in another independent wild population by targeted gene re-sequencing and SNPshot analysis. After screening the single nucleotide polymorphisms (SNPs) in three candidate genes of the bHLH family (88 bHLH genes in two wild oyster populations in total), we identified the allele CgLoblHLH4-T/G located in the exon of the CgLoblHLH4 gene. This allele is a non-synonymous mutation (Phe/Leu) with an extremely significant association with shell width (P<0.01) and allele G is beneficial to shell width. This SNP on the CgLoblHLH4 gene might have a potential value as a genetic marker of growth traits that could be used in breeding in C. gigas in the future.
关键词	Crassostrea gigas basic helix-loop-helix (bHLH) re-sequencing single nucleotide polymorphism (SNP) shot growth traits
DOI	10.1007/s00343-019-9070-4
收录类别	SCI
语种	英语
资助项目	Zhejiang Provincial Major Program of Science and Technology[2016C02055-9]###3464; Ningbo Municipal Science and Technology International Cooperation Research Projects[2016D10017]###3463; National Natural Science Foundation of China[31672678]###3462; National Key R&D Program of China[2018YFD0901400]###3461; National Key R&D Program of China[2018YFD0901400]; National Natural Science Foundation of China[31672678]; Ningbo Municipal Science and Technology International Cooperation Research Projects[2016D10017]; Zhejiang Provincial Major Program of Science and Technology[2016C02055-9]
WOS研究方向	Marine & Freshwater Biology ; Oceanography
WOS类目	Limnology ; Oceanography
WOS记录号	WOS:000500871700004
出版者	SCIENCE PRESS
引用统计	被引频次：2[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
版本	出版稿
条目标识符	http://ir.qdio.ac.cn/handle/337002/163853
专题	实验海洋生物学重点实验室
通讯作者	Bao Yongbo
作者单位	1.Zhejiang Wanli Univ, Coll Biol & Environm Sci, Zhejiang Key Lab Aquat Germplasm Resources, Ningbo 315121, Zhejiang, Peoples R China 2.Ningbo Univ, Sch Marine Sci, Ningbo 315211, Zhejiang, Peoples R China 3.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao 266071, Shandong, Peoples R China
推荐引用方式 GB/T 7714	Chen Na,Li Li,Li Chenghua,et al. bHLH genes polymorphisms and their association with growth traits in the Pacific oyster Crassostrea gigas[J]. JOURNAL OF OCEANOLOGY AND LIMNOLOGY,2019:7.
APA	Chen Na.,Li Li.,Li Chenghua.,Lin Zhihua.,Meng Jie.,...&Bao Yongbo.(2019).bHLH genes polymorphisms and their association with growth traits in the Pacific oyster Crassostrea gigas.JOURNAL OF OCEANOLOGY AND LIMNOLOGY,7.
MLA	Chen Na,et al."bHLH genes polymorphisms and their association with growth traits in the Pacific oyster Crassostrea gigas".JOURNAL OF OCEANOLOGY AND LIMNOLOGY (2019):7.

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