Institutional Repository of Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences
| Antimicrobial bisabolane-type sesquiterpenoids from the deep-sea sediment-derived fungus Aspergillus versicolor SD-330 | |
Li, Xiao-Dong1,2 ; Li, Xin1,3,4; Li, Xiao-Ming1,3,4; Yin, Xiu-Li2; Wang, Bin-Gui1,3,4
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| 2019-11-28 | |
| 发表期刊 | NATURAL PRODUCT RESEARCH
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| ISSN | 1478-6419 |
| 页码 | 7 |
| 通讯作者 | Wang, Bin-Gui([email protected]) |
| 摘要 | One new aromatic bisabolene-type sesquiterpenoid (1), along with four known analogues (2-5) were isolated and identified from the deep-sea sediment-derived fungus Aspergillus versicolor SD-330. Their structures were elucidated by NMR, HRESIMS, X-ray crystallographic analysis, and quantum chemical ECD calculations as well as comparison of those data with literature data. Compounds 1-5 were evaluated for antimicrobial activities against human and aquatic pathogenic bacteria. Compounds 1, 2 and 5 exhibited selective inhibitory activities against zoonotic pathogenic bacteria such as Aeromonas hydrophilia, Escherichia coli, Edwardsiella tarda and Vibrio harveyi, with the MIC values ranging from 1.0 to 8.0 mu g/mL. |
| 关键词 | Aspergillus versicolor deep-sea sediment-derived fungus bisabolene-type sesquiterpenoids antimicrobial activity |
| DOI | 10.1080/14786419.2019.1696792 |
| 收录类别 | SCI |
| 语种 | 英语 |
| 资助项目 | Aoshan Scientific and Technological Innovation Project of Qingdao National Laboratory for Marine Science and Technology[2016ASKJ14]###698; National Natural Science Foundation of China[31700043]###697; National Natural Science Foundation of China[81600672]###3441; Key Research and Development Program of Shandong Province[2019GSF107091]###3442; China Postdoctoral Science Foundation[2016LH00033]###3419; China Postdoctoral Science Foundation[2017M612358]###3420; China Postdoctoral Science Foundation[2017M612360]###3421; Research Vessel KEXUE of the National Major Science and Technology Infrastructure from the Chinese Academy of Sciences[KEXUE2018G28]###3422; Taishan Scholar Project from Shandong Province###1179; Shandong Provincial Natural Science Foundation[ZR2017BB073]###2465; Aoshan Scientific and Technological Innovation Project of Qingdao National Laboratory for Marine Science and Technology[2016ASKJ14]; National Natural Science Foundation of China[31700043]; National Natural Science Foundation of China[81600672]; Key Research and Development Program of Shandong Province[2019GSF107091]; China Postdoctoral Science Foundation[2016LH00033]; China Postdoctoral Science Foundation[2017M612358]; China Postdoctoral Science Foundation[2017M612360]; Research Vessel KEXUE of the National Major Science and Technology Infrastructure from the Chinese Academy of Sciences[KEXUE2018G28]; Taishan Scholar Project from Shandong Province; Shandong Provincial Natural Science Foundation[ZR2017BB073] |
| WOS研究方向 | Chemistry ; Pharmacology & Pharmacy |
| WOS类目 | Chemistry, Applied ; Chemistry, Medicinal |
| WOS记录号 | WOS:000501477400001 |
| 出版者 | TAYLOR & FRANCIS LTD |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.qdio.ac.cn/handle/337002/163820 |
| 专题 | 实验海洋生物学重点实验室 |
| 通讯作者 | Wang, Bin-Gui |
| 作者单位 | 1.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao, Shandong, Peoples R China 2.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Biol & Biotechnol, Qingdao, Shandong, Peoples R China 3.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai, Peoples R China 4.Chinese Acad Sci, Ctr Ocean Megasci, Qingdao, Shandong, Peoples R China |
| 第一作者单位 | 中国科学院海洋研究所 |
| 通讯作者单位 | 中国科学院海洋研究所; 中国科学院海洋大科学研究中心 |
| 推荐引用方式 GB/T 7714 | Li, Xiao-Dong,Li, Xin,Li, Xiao-Ming,et al. Antimicrobial bisabolane-type sesquiterpenoids from the deep-sea sediment-derived fungus Aspergillus versicolor SD-330[J]. NATURAL PRODUCT RESEARCH,2019:7. |
| APA | Li, Xiao-Dong,Li, Xin,Li, Xiao-Ming,Yin, Xiu-Li,&Wang, Bin-Gui.(2019).Antimicrobial bisabolane-type sesquiterpenoids from the deep-sea sediment-derived fungus Aspergillus versicolor SD-330.NATURAL PRODUCT RESEARCH,7. |
| MLA | Li, Xiao-Dong,et al."Antimicrobial bisabolane-type sesquiterpenoids from the deep-sea sediment-derived fungus Aspergillus versicolor SD-330".NATURAL PRODUCT RESEARCH (2019):7. |
| 条目包含的文件 | ||||||
| 文件名称/大小 | 文献类型 | 版本类型 | 开放类型 | 使用许可 | ||
| Antimicrobial bisabo（1085KB） | 期刊论文 | 出版稿 | 限制开放 | CC BY-NC-SA | 浏览 | |
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