Bromophenols from the marine red alga Polysiphonia urceolata with DPPH radical scavenging activity

doi:10.1021/np070281p

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	Bromophenols from the marine red alga Polysiphonia urceolata with DPPH radical scavenging activity
	Li, Ke 1,2; Li, Xiao-Ming 1; Ji, Nai-Yun 1,2; Wang, Bin-Gui1 ; Wang, BG, Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Nanhai Rd 7, Qingdao 266071, Peoples R China
	2008
发表期刊	JOURNAL OF NATURAL PRODUCTS
ISSN	0163-3864
卷号	71 期号:1 页码:28-30
文章类型	Article
摘要	Three new (1-3) and three known (4-6) bromophenols were isolated and identified from the marine red alga Polysiphonia urceolata. On the basis of extensive analysis of spectroscopic data, the structures of these compounds were determined to be 7-bromo-9,10-dihydrophenanthrene-2,3,5,6-tetraol (1), 4,7-dibromo-9,10-dihydrophenanthrene-2,3,5,6-tetraol (2), 1,8-dibromo-5,7-dihydrodibenzo[c,e]oxepine-2,3,9,10-tetraol (3), urceolatol (4), 3-,bromo-4,5-dihydroxybenzaidehyde (5), and 3,5-dibromo-4-hydroxybenzaldehyde (6). Each of the isolated compounds was evaluated for alpha,alpha-dipheny1-beta-picrylhydrazyl (DPPH) radical scavenging activity, and all were found to be potent, with IC50 values ranging from 6.1 to 35.8 mu M, compared to the positive control, butylated hydroxytoluene (BHT), with an IC50 of 83.8 mu M.; Three new (1-3) and three known (4-6) bromophenols were isolated and identified from the marine red alga Polysiphonia urceolata. On the basis of extensive analysis of spectroscopic data, the structures of these compounds were determined to be 7-bromo-9,10-dihydrophenanthrene-2,3,5,6-tetraol (1), 4,7-dibromo-9,10-dihydrophenanthrene-2,3,5,6-tetraol (2), 1,8-dibromo-5,7-dihydrodibenzo[c,e]oxepine-2,3,9,10-tetraol (3), urceolatol (4), 3-,bromo-4,5-dihydroxybenzaidehyde (5), and 3,5-dibromo-4-hydroxybenzaldehyde (6). Each of the isolated compounds was evaluated for alpha,alpha-dipheny1-beta-picrylhydrazyl (DPPH) radical scavenging activity, and all were found to be potent, with IC50 values ranging from 6.1 to 35.8 mu M, compared to the positive control, butylated hydroxytoluene (BHT), with an IC50 of 83.8 mu M.
关键词	Symphyocladia-latiuscula Rhodomela-confervoides Derivatives Fractions
学科领域	Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy
DOI	10.1021/np070281p
URL	查看原文
收录类别	SCI ; IC
语种	英语
WOS记录号	WOS:000252629400007
引用统计	被引频次：66[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.qdio.ac.cn/handle/337002/1637
专题	实验海洋生物学重点实验室
通讯作者	Wang, BG, Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Nanhai Rd 7, Qingdao 266071, Peoples R China
作者单位	1.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China
第一作者单位	实验海洋生物学重点实验室
推荐引用方式 GB/T 7714	Li, Ke,Li, Xiao-Ming,Ji, Nai-Yun,et al. Bromophenols from the marine red alga Polysiphonia urceolata with DPPH radical scavenging activity[J]. JOURNAL OF NATURAL PRODUCTS,2008,71(1):28-30.
APA	Li, Ke,Li, Xiao-Ming,Ji, Nai-Yun,Wang, Bin-Gui,&Wang, BG, Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Nanhai Rd 7, Qingdao 266071, Peoples R China.(2008).Bromophenols from the marine red alga Polysiphonia urceolata with DPPH radical scavenging activity.JOURNAL OF NATURAL PRODUCTS,71(1),28-30.
MLA	Li, Ke,et al."Bromophenols from the marine red alga Polysiphonia urceolata with DPPH radical scavenging activity".JOURNAL OF NATURAL PRODUCTS 71.1(2008):28-30.

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