Institutional Repository of Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences
| A global view of hepatopancreas and intestinal reveals the potential influencing mechanism of aflatoxin B1 on nutrition and metabolism in Litopenaeus vannamei | |
Wang, Yilong1,2,3 ; Liu, Mei1,2; Wang, Baojie1,2; Jiang, Keyong1,2; Wang, Mengqiang1,2,4; Wang, Lei1,2,5
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| 2019-08-12 | |
| 发表期刊 | AQUACULTURE NUTRITION
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| ISSN | 1353-5773 |
| 页码 | 13 |
| 通讯作者 | Wang, Mengqiang([email protected]) ; Wang, Lei([email protected]) |
| 摘要 | The present study was to determine the time-dependent alterations in growth performance, histomorphology, digestive enzymes activities and the genes expression related to target of rapamycin (TOR) signalling pathway involved in hepatopancreas and intestine of Litopenaeus vannamei at 3, 6, 12, 18, 24 and 30 days after Aflatoxin B1 (AFB1) challenge. The results manifested that AFB1 could induce a significant decrease in growth performance and visible variations of the hepatopancreas and intestine structures in shrimp. Meanwhile, the digestive enzymes activities and genes expression level were significantly lower in the experimental group than in the control group and showed a time-dependent decrease (p < 0.05). The expression levels of tor and s6k were significantly higher in the experimental group than in the control group from days 6 to 24 and showed a tendency to increase first and then decrease as a whole (p < 0.05). Meanwhile, we analysed candidate pathways involved in hepatopancreas and intestine of shrimp in metabolic response to AFB1. The mainly disturbed pathways related to metabolism in hepatopancreas were involved in pyrimidine, glycosylphosphatidylinositol, glycosaminoglycan, vitamin and amino acid biosynthesis and metabolism, while the mainly disturbed metabolic pathways in intestine were glycosaminoglycan, vitamin and amino acid biosynthesis and metabolism. |
| 关键词 | aflatoxin B1 hepatopancreas intestinal Litopenaeus vannamei metabolism |
| DOI | 10.1111/anu.12956 |
| 收录类别 | SCI |
| 语种 | 英语 |
| 资助项目 | Major Scientific and Technological Innovation Project, Shandong Province, China[2018SDKJ0502-2]###3002; Science and Technology Development Fund Project of Shinan District, Qingdao City, China[2018-4-001-ZH]###3003; Major Scientific and Technological Innovation Project, Shandong Province, China[2018SDKJ0502-2]; Science and Technology Development Fund Project of Shinan District, Qingdao City, China[2018-4-001-ZH] |
| WOS研究方向 | Fisheries |
| WOS类目 | Fisheries |
| WOS记录号 | WOS:000481032400001 |
| 出版者 | WILEY |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.qdio.ac.cn/handle/337002/162349 |
| 专题 | 实验海洋生物学重点实验室 |
| 通讯作者 | Wang, Mengqiang; Wang, Lei |
| 作者单位 | 1.Chinese Acad Sci, Inst Oceanol, CAS Key Lab Expt Marine Biol, Qingdao, Shandong, Peoples R China 2.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Biol & Biotechnol, Qingdao, Shandong, Peoples R China 3.Univ Chinese Acad Sci, Beijing, Peoples R China 4.Natl Lab Marine Sci & Technol, Res Platform Marine Mol Biotechnol, Qingdao, Shandong, Peoples R China 5.Chinese Acad Sci, CAS Ctr Ocean Mega Sci, Qingdao, Shandong, Peoples R China |
| 第一作者单位 | 中国科学院海洋研究所 |
| 通讯作者单位 | 中国科学院海洋研究所 |
| 推荐引用方式 GB/T 7714 | Wang, Yilong,Liu, Mei,Wang, Baojie,et al. A global view of hepatopancreas and intestinal reveals the potential influencing mechanism of aflatoxin B1 on nutrition and metabolism in Litopenaeus vannamei[J]. AQUACULTURE NUTRITION,2019:13. |
| APA | Wang, Yilong,Liu, Mei,Wang, Baojie,Jiang, Keyong,Wang, Mengqiang,&Wang, Lei.(2019).A global view of hepatopancreas and intestinal reveals the potential influencing mechanism of aflatoxin B1 on nutrition and metabolism in Litopenaeus vannamei.AQUACULTURE NUTRITION,13. |
| MLA | Wang, Yilong,et al."A global view of hepatopancreas and intestinal reveals the potential influencing mechanism of aflatoxin B1 on nutrition and metabolism in Litopenaeus vannamei".AQUACULTURE NUTRITION (2019):13. |
| 条目包含的文件 | ||||||
| 文件名称/大小 | 文献类型 | 版本类型 | 开放类型 | 使用许可 | ||
| anu.12956.pdf（1830KB） | 期刊论文 | 出版稿 | 限制开放 | CC BY-NC-SA | 浏览 | |
| A global view of hep（1779KB） | 期刊论文 | 出版稿 | 限制开放 | CC BY-NC-SA | 浏览 | |
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